50 Participants Needed

Virtual Reality Therapy for Vertigo

(VR-PVD-RCT Trial)

LE
AH
Overseen ByAustin Heffernan, BMSc
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of British Columbia
Stay on Your Current MedsYou can continue your current medications while participating
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether virtual reality (VR) therapy can reduce vertigo symptoms in individuals with vestibular (inner ear) issues. Participants will be divided into two groups: one will use VR headsets at home as part of their therapy (Standard Vestibular Rehabilitation with Adjunct At Home Virtual Reality Vestibular Rehabilitation), while the other will follow a standard rehabilitation program with added auditory stimulation (Standard Vestibular Rehabilitation with Adjunct Auditory Intervention). Researchers aim to determine if the location of the ear problem influences the effectiveness of VR therapy. Individuals who have had a vestibular disorder for at least three months and are already undergoing vestibular rehab might be suitable candidates, especially if they have access to a smartphone. As an unphased trial, this study provides a unique opportunity to explore innovative therapy options that could enhance current treatment plans.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this virtual reality therapy is safe for vertigo patients?

Research shows that virtual reality (VR) is becoming a useful tool for people with balance and dizziness problems. Previous studies have found that VR-based programs are as effective as traditional therapy. Most people handle VR well, experiencing few serious side effects.

One study found that VR reduces symptoms and improves balance, similar to regular therapy. Many patients find VR engaging, which encourages them to continue treatment.

Overall, using VR for balance therapy appears safe. It complements standard treatments and offers an interactive way to manage symptoms. While some might experience mild discomfort, such as dizziness, these feelings usually don't last long.12345

Why are researchers excited about this trial?

Researchers are excited about using virtual reality (VR) therapy for vertigo because it offers a novel way to enhance traditional vestibular rehabilitation. Unlike standard treatments that rely solely on physical exercises, this approach integrates immersive VR experiences to stimulate the vestibular system more effectively. The VR therapy allows patients to engage in interactive exercises that mimic real-life scenarios, potentially speeding up recovery by making the rehab process more engaging and personalized. Additionally, the convenience of at-home VR sessions means patients can consistently practice without needing frequent clinic visits, promoting better adherence to the rehabilitation regimen.

What evidence suggests that virtual reality therapy is effective for vertigo?

Research shows that virtual reality (VR) therapy can help people with balance problems. In this trial, participants in the Virtual Reality Group will follow a VR vestibular rehabilitation protocol, which involves playing a video game projected on a device in a VR headset. Studies have found that adding VR games to regular balance exercises can improve balance and reduce dizziness. For example, patients using VR headsets achieved better results than those using only traditional methods. One study found that VR-based therapy was as effective as conventional therapy, making it a strong alternative. Overall, solid evidence supports VR therapy's effectiveness in improving symptoms in people with balance disorders.12367

Who Is on the Research Team?

DA

Desmond A Nunez, MD, MBA

Principal Investigator

Division of Otolaryngology, Department of Surgery, The University of British Columbia

Are You a Good Fit for This Trial?

This trial is for adults over 18 with chronic peripheral vestibular disorders like vertigo or Meniere's Disease, diagnosed using specific tests. They must have had the condition for at least 3 months and be prescribed vestibular rehabilitation. Participants need to have access to a smartphone.

Inclusion Criteria

Access to an android or iOS smart phone
My diagnosis was confirmed with specific balance tests.
I have been diagnosed with a long-term (3+ months) inner ear disorder.
See 1 more

Exclusion Criteria

Pregnant participants
I have been diagnosed with a balance disorder related to my brain.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2 weeks
Remote assessment via phone or Zoom

Baseline Assessment

Baseline data collection including symptomatology questionnaires and patient interviews

2 weeks
Remote assessment via phone or Zoom

Treatment

Participants undergo 4 to 8 weeks of vestibular rehabilitation with weekly in-person sessions and daily at-home exercises. The VR group also uses a VR headset for 20 minutes daily.

4 to 8 weeks
Weekly in-person sessions, daily at-home exercises

Follow-up

Participants are monitored for changes in symptomatology and return VR headsets

2 weeks
Remote assessment and return of equipment

What Are the Treatments Tested in This Trial?

Interventions

  • Standard Vestibular Rehabilitation with Adjunct At Home Virtual Reality Vestibular Rehabilitation
  • Standard Vestibular Rehabilitation with Adjunct Auditory Intervention
Trial Overview The study compares standard vestibular rehab with two additions: auditory intervention and at-home VR therapy, to see if VR helps improve symptoms based on where the disorder is located in the ear. Patients are randomly placed into groups and follow treatment protocols for up to 8 weeks.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Virtual Reality GroupExperimental Treatment1 Intervention
Group II: Control GroupActive Control1 Intervention

Standard Vestibular Rehabilitation with Adjunct At Home Virtual Reality Vestibular Rehabilitation is already approved in United States, European Union for the following indications:

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Approved in United States as Virtual Reality Vestibular Rehabilitation for:
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Approved in European Union as VR Vestibular Therapy for:

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of British Columbia

Lead Sponsor

Trials
1,506
Recruited
2,528,000+

Published Research Related to This Trial

In a study of 74 participants with chronic dizziness, those who received expert physiotherapist guidance in a home-based vestibular rehabilitation therapy (VRT) program showed significantly greater improvement in their dizziness scores compared to those who exercised without specific instructions.
Both groups improved over the 8-week study, but the intervention group experienced a more substantial reduction in their Dizziness Handicap Inventory scores, highlighting the importance of tailored instructions for maximizing the effectiveness of home exercise programs.
Specific and individualized instructions improve the efficacy of booklet-based vestibular rehabilitation at home - a randomized controlled trial (RCT).Kellerer, S., Amberger, T., Schlick, C., et al.[2023]
In a study of 20 patients with unilateral vestibular hypofunction, virtual reality (VR) vestibular rehabilitation was evaluated and compared to conventional therapy, showing promising results in improving symptoms of vertigo.
Both VR and conventional therapy groups reported significant improvements in their symptoms, indicating that VR may be an effective alternative for vestibular rehabilitation, although specific statistical outcomes were not detailed.
Virtual Reality Vestibular Rehabilitation in 20 Patients with Vertigo Due to Peripheral Vestibular Dysfunction.Stankiewicz, T., Gujski, M., Niedzielski, A., et al.[2021]
The study identified two virtual reality games, VR Tunnel Race (VRTR) and VR Real World Bike Racing (VRWBR), as the most effective options for enhancing vestibular rehabilitation therapy, based on assessments from 40 physiotherapists.
VRTR was found to replicate habituation exercises significantly better than another game, while VRWBR was noted for its ease of use and flexibility in adjusting optokinetic stimulation, suggesting it may be the preferred choice for therapy.
Vestibular rehabilitation potential of commercially available virtual reality video games.Heffernan, A., Booth, L., Fletcher, R., et al.[2023]

Citations

Vestibular rehabilitation potential of commercially available ...Previous studies demonstrated that at home virtual reality racing games were effective as adjunctive vestibular rehabilitation [19, 20] ...
Effect of Peripheral Vestibular Disease Location on ...The virtual reality intervention will involve standard vestibular rehabilitation as described above and adjunct at home virtual reality video game. This video ...
Virtual reality-based vestibular rehabilitation therapy in ...This study aimed to assess the effects of VRT using head-mounted display (HMD) VR technology in patients with acute unilateral vestibulopathy (AUVP)
Virtual and augmented reality in the vestibular ...Evidence of the efficacy of VR and AR delivered rehabilitation in patients with peripheral vestibular disorders is reviewed.
Can virtual reality replace conventional vestibular ...This study aimed to determine whether a virtual reality (VR)-based rehabilitation program using HMDs is non-inferior to a conventional program.
Journal of Neurologic Physical TherapyThere is strong evidence supporting vestibular physical therapy for reducing symptoms, improving gaze and postural stability, and improving function.
Clinical application of virtual reality for vestibular ...Virtual reality has emerged as a promising tool in vestibular rehabilitation therapy (VRT), offering immersive and interactive environments that ...
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