Ketamine for Hemorrhoids
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests if ketamine can help reduce pain in patients having surgery for severe hemorrhoids. Ketamine is given during the operation to block pain signals in the brain. The study compares patients who receive ketamine with those who do not. Ketamine has been studied for its potential to reduce postoperative pain and opioid consumption, but results have been mixed.
Do I need to stop my current medications for the trial?
The trial information does not specify if you need to stop taking your current medications. However, if you are using narcotics regularly, you must stop at least one month before the hemorrhoidectomy.
Is ketamine generally safe for humans?
How does the drug ketamine differ from other treatments for hemorrhoids?
Ketamine is unique because it is typically used as an anesthetic and pain reliever, often administered through injections or oral forms like gels or lollipops, which is different from standard hemorrhoid treatments that usually involve topical creams or surgical procedures. Its use for hemorrhoids is novel, as it leverages ketamine's pain-relieving properties in a new context.678910
What data supports the effectiveness of the drug ketamine for treating hemorrhoids?
Who Is on the Research Team?
Steven Carter, MD
Principal Investigator
University of Oklahoma
Are You a Good Fit for This Trial?
This trial is for adults aged 18-100 who are having surgery (hemorrhoidectomy) for severe hemorrhoids (Grade III or IV). They must be able to have general anesthesia and not use strong painkillers regularly. People with a history of schizophrenia, other hallucinatory psychiatric illnesses, or psychosis cannot participate.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo hemorrhoidectomy with either intraoperative ketamine infusion or standard anesthesia
Post-operative Monitoring
Participants' post-operative pain is assessed using a numeric rating scale and the Wong-Baker FACES pain scale
Follow-up
Participants are monitored for safety and effectiveness after treatment, including assessment of narcotic usage
What Are the Treatments Tested in This Trial?
Interventions
- Ketamine
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Oklahoma
Lead Sponsor