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What is Vilazodone Hydrochloride
VilazodoneThe Generic name of this drug
Treatment SummaryVilazodone is a medication used to treat depression. It works by targeting both serotonin transporters and serotonin receptors in the brain. It is associated with fewer side effects such as sexual dysfunction and weight gain when compared to other antidepressant medications. It was approved by the FDA in 2011.
Viibrydis the brand name
Vilazodone Hydrochloride Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Viibryd
Vilazodone
2011
41
Approved as Treatment by the FDA
Vilazodone, also known as Viibryd, is approved by the FDA for 1 uses such as Depression .Depression
Effectiveness
How Vilazodone Hydrochloride Affects PatientsVilazodone boosts serotonin levels in the brain by blocking the removal of serotonin, while also activating serotonin-1A receptors. This combination of effects has earned vilazodone the nickname of SPARI, which stands for selective partial agonist and reuptake inhibitor.
How Vilazodone Hydrochloride works in the bodyVilazodone works on two levels to reduce depressive symptoms. It blocks the reuptake of serotonin in the brain, keeping more of the feel-good hormone in circulation. It also activates the 5HT-1A receptor, which is thought to be linked to decreased depression.
When to interrupt dosage
The advised dosage of Vilazodone Hydrochloride is reliant upon the specified condition. The amount of dosage fluctuates as per the method of administration (e.g. Tablet - Oral or Tablet, film coated - Oral) noted in the table beneath.Condition
Dosage
Administration
Depression
, 40.0 mg, 10.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Kit; Tablet - Oral, Kit; Tablet, Kit, Kit - Oral, Tablet, film coated, Tablet, film coated - Oral
Warnings
Vilazodone Hydrochloride ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Common Vilazodone Hydrochloride Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Ethanol
Major
Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Methylene blue
Major
Vilazodone may increase the serotonergic activities of Methylene blue.
Mirtazapine
Major
Vilazodone may increase the serotonergic activities of Mirtazapine.
Oliceridine
Major
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Vilazodone is combined with Oliceridine.
Vilazodone Hydrochloride Toxicity & Overdose RiskThere have not been any studies done on vilazodone in pregnant women, but animal studies have shown that it could lead to reduced fetal weight, increased mortality, delayed development, and decreased fertility at doses much higher than the recommended amount for humans. Also, there have been cases of infants and newborns exposed to SSRIs and SNRIs who experienced problems such as breathing difficulties, seizures, and trouble regulating their body temperature. It is not known if vilazodone is present in breast milk, but animal studies have shown that it is present in rats. Before deciding to breastfeed while taking vilazodone, the benefits
Vilazodone Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Vilazodone Hydrochloride?
186 active clinical trials are examining the potential of Vilazodone Hydrochloride to alleviate symptoms of Depression.Condition
Clinical Trials
Trial Phases
Depression
198 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Phase 4, Early Phase 1
Vilazodone Hydrochloride Reviews: What are patients saying about Vilazodone Hydrochloride?
4.7Patient Review
2/7/2013 I thought this drug was quite effective. I had better results with Wellbutrin, but it also came with more side effects.
4.7Patient Review
6/17/2018 I found that 20mg was the perfect amount for me, giving me lots of energy and helping me focus. I tried going up to 40mg, but found that my anxiety increased too much.
4.3Patient Review
4/26/2014 I experienced a lot of muscle cramps when I first started taking this medication, but they quickly subsided. I've been generally pleased with its effectiveness in treating my depression.
4Patient Review
11/29/2012 I was always tired, even after working out at the gym. I had low libido and difficulties with erections, plus my muscles would always get fatigued easily. If I missed a dose, I would have horrible dreams. And if I drank alcohol while taking the medication, I would feel really awful. On the bright side, I didn't experience many visual problems.
4Patient Review
1/22/2013 Viibryd can cause some serious problems if taken alongside Straterra. I would recommend avoiding this combination as it can lead to hospitalization due to major depression.
3.7Patient Review
11/22/2012 I experienced a lot of side effects while taking this drug, including tingling cravings (both at the beginning and the end), diarrhea, and sexual dysfunction.
3.7Patient Review
9/22/20113Patient Review
8/1/2012 This treatment is okay. It helped a little bit, but I didn't see a huge difference.
2.3Patient Review
8/28/2013 I developed a burning, peeling rash after only three weeks of use. Six weeks later and I'm still dealing with the same issue. Additionally, I now have mouth sores that aren't healing. The doctor was no help whatsoever and just told me to stop taking the medication. What am I supposed to do now?
2.3Patient Review
3/19/2014 This medication did not help me at all. If anything, it made things worse.
2Patient Review
9/19/2022 I'm three weeks in and I don't feel like this medication has helped me mood-wise at all. If anything, it's made me more tired, less interested in sex, and nauseous. I'm only on a 10 MG dose, so I don't think increasing the dosage would help matters.
Patient Q&A Section about vilazodone hydrochloride
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What kind of antidepressant is vilazodone?
"Vilazodone is used to treat depression and it works by preventing the reuptake of serotonin in the brain."
Answered by AI
Is vilazodone a good antidepressant?
"The evidence does not support the use of vilazodone for routine depression treatment. It is more expensive than generic alternatives, and no more effective for moderate to severe depression than other medications."
Answered by AI
What is vilazodone used for?
"Vilazodone is used to treat depression in adults by increasing the activity of a chemical called serotonin in the brain."
Answered by AI
What are the side effects of vilazodone?
"You may experience diarrhea, nausea, vomiting, dizziness, or trouble sleeping. If you experience any of these effects for an extended period of time, or if they worsen, contact your doctor or pharmacist. Keep in mind that your doctor prescribed this medication because they believe that the benefits outweigh the risks of side effects."
Answered by AI