Vascepa

Diabetes, Cardiovascular Events, Diet + 4 more
Treatment
8 FDA approvals
20 Active Studies for Vascepa

What is Vascepa

Icosapent ethylThe Generic name of this drug
Treatment SummaryIcosapent Ethyl is a synthetic form of omega-3 fatty acid eicosapentaenoic acid (EPA). It is used to treat high levels of triglycerides in the blood (above 500 mg/dL), when other treatments have failed. The FDA approved Icosapent Ethyl in 2012.
Vascepais the brand name
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Vascepa Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Vascepa
Icosapent ethyl
2012
14

Approved as Treatment by the FDA

Icosapent ethyl, otherwise known as Vascepa, is approved by the FDA for 8 uses such as Diabetes Mellitus and elevation of serum triglyceride levels .
Diabetes Mellitus
elevation of serum triglyceride levels
Diabetes
Cardiovascular Events
Hospitalizations
Cardiovascular Disease
Hypertriglyceridemia
Cardiovascular Diseases

Effectiveness

How Vascepa works in the bodyStudies suggest that EPA reduces triglycerides in the liver and increases the rate of triglyceride breakdown in the body. This is likely due to increased fat burning, decreased fat creation, and increased breakdown of fat in the bloodstream.

When to interrupt dosage

The suggested amount of Vascepa hinges on the determined condition. The dosage also depends on the mode of administration outlined in the table below.
Condition
Dosage
Administration
Diabetes
, 1000.0 mg, 500.0 mg, 0.625 mg, 998.0 mg
, Oral, Capsule, Capsule - Oral, Tablet, coated - Oral, Tablet, coated
Cardiovascular Events
, 1000.0 mg, 500.0 mg, 0.625 mg, 998.0 mg
, Oral, Capsule, Capsule - Oral, Tablet, coated - Oral, Tablet, coated
Cardiovascular Disease
, 1000.0 mg, 500.0 mg, 0.625 mg, 998.0 mg
, Oral, Capsule, Capsule - Oral, Tablet, coated - Oral, Tablet, coated
Hypertriglyceridemia
, 1000.0 mg, 500.0 mg, 0.625 mg, 998.0 mg
, Oral, Capsule, Capsule - Oral, Tablet, coated - Oral, Tablet, coated
Cardiovascular Diseases
, 1000.0 mg, 500.0 mg, 0.625 mg, 998.0 mg
, Oral, Capsule, Capsule - Oral, Tablet, coated - Oral, Tablet, coated
Diet
, 1000.0 mg, 500.0 mg, 0.625 mg, 998.0 mg
, Oral, Capsule, Capsule - Oral, Tablet, coated - Oral, Tablet, coated
Hospitalizations
, 1000.0 mg, 500.0 mg, 0.625 mg, 998.0 mg
, Oral, Capsule, Capsule - Oral, Tablet, coated - Oral, Tablet, coated

Warnings

Vascepa Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Icosapent Ethyl may interact with Pulse Frequency
There are 20 known major drug interactions with Vascepa.
Common Vascepa Drug Interactions
Drug Name
Risk Level
Description
Abrocitinib
Major
The risk or severity of bleeding and thrombocytopenia can be increased when Icosapent ethyl is combined with Abrocitinib.
Aldesleukin
Minor
The risk or severity of bleeding can be increased when Icosapent ethyl is combined with Aldesleukin.
Alemtuzumab
Minor
The risk or severity of bleeding can be increased when Icosapent ethyl is combined with Alemtuzumab.
Altretamine
Minor
The risk or severity of bleeding can be increased when Icosapent ethyl is combined with Altretamine.
Amsacrine
Minor
The risk or severity of bleeding can be increased when Icosapent ethyl is combined with Amsacrine.
Vascepa Toxicity & Overdose RiskIcosapent ethyl is generally safe to use and unlikely to cause any adverse reactions.
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Vascepa Novel Uses: Which Conditions Have a Clinical Trial Featuring Vascepa?

Four active clinical trials are presently underway to assess the efficacy of Vascepa in managing Hypertriglyceridemia.
Condition
Clinical Trials
Trial Phases
Diabetes
75 Actively Recruiting
Phase 1, Not Applicable, Phase 4, Phase 2, Phase 3
Hospitalizations
4 Actively Recruiting
Not Applicable
Cardiovascular Events
4 Actively Recruiting
Not Applicable
Diet
5 Actively Recruiting
Not Applicable, Phase 1
Hypertriglyceridemia
0 Actively Recruiting
Cardiovascular Diseases
0 Actively Recruiting
Cardiovascular Disease
22 Actively Recruiting
Not Applicable, Early Phase 1, Phase 3, Phase 2

Vascepa Reviews: What are patients saying about Vascepa?

5Patient Review
1/24/2020
Vascepa for Primary Prevention of Heart Attack
I started this treatment in March 2018 with no problems whatsoever. My bloodwork has actually shown improvement, and I feel great about my heart health in general. Sign up for the coupon at vasecpa savings plan--it's worth it! Also, ignore the bad reviews; they're probably from a competitor. This product is a game changer!
5Patient Review
6/8/2019
Vascepa for High Amount of Triglyceride in the Blood
I'm so happy that this drug has been able to help me in so many ways. Not only have my lipids improved, but I've also experienced less brain fog and overall inflammation. I haven't had any negative side effects, which is amazing.
5Patient Review
12/19/2019
Vascepa for High Amount of Triglyceride in the Blood
I had no issues whatsoever with this drug, and it worked great! I don't know what people are talking about when they say they've experienced side effects.
4.3Patient Review
3/3/2020
Vascepa for High Amount of Triglyceride in the Blood
I switched to Vascepa from the generic EPA, and it worked well for me. The cost is a bit high, though.
3.3Patient Review
7/27/2022
Vascepa for Treatment to Prevent a Heart Attack
Although this treatment didn't have the intended effect of decreasing my cholesterol (as shown by bloodwork), it also didn't come with any negative side effects.
View All Reviews
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Patient Q&A Section about vascepa

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Vascepa the same thing as fish oil?

"Vascepa is an omega-3 fatty acid supplement that contains only EPA, while most fish oil supplements contain EPA and DHA."

Answered by AI

What are the side effects of Vascepa?

"Muscle and joint pain, constipation, swelling in extremities, gout, and chest pressure are all possible side effects of the medication."

Answered by AI

What is the medical Vascepa used for?

"Vascepa has been FDA-approved to lower blood triglyceride levels in adults with severe hypertriglyceridemia."

Answered by AI

Does Vascepa cause weight loss?

"As of February 17th, 2022, there are no documented reports which state that Vascepa is an effective way to lose weight."

Answered by AI

Clinical Trials for Vascepa

Have you considered Vascepa clinical trials? We made a collection of clinical trials featuring Vascepa, we think they might fit your search criteria.
Have you considered Vascepa clinical trials? We made a collection of clinical trials featuring Vascepa, we think they might fit your search criteria.
Have you considered Vascepa clinical trials? We made a collection of clinical trials featuring Vascepa, we think they might fit your search criteria.
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