Theochron
Acute Bronchitis, Bronchial Spasm, Asthma + 8 more
Treatment
7 FDA approvals
20 Active Studies for Theochron
Treatment for
Acute Bronchitis
What is Theochron
Theophylline
The Generic name of this drug
Treatment Summary
Theophylline is a drug derived from tea that can be used as a diuretic, muscle relaxant, and bronchodilator. It works by blocking certain receptors, inhibiting an enzyme called phosphodiesterase, and activating histone deacetylase. It is sold under the brand names Uniphyl and Theochron and is mainly used to treat asthma, bronchospasm, and chronic obstructive pulmonary disease (COPD).
Elixophyllin
is the brand name
Theochron Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Elixophyllin
Theophylline
1979
114
Approved as Treatment by the FDA
Theophylline, commonly known as Elixophyllin, is approved by the FDA for 7 uses like Chronic Bronchitis and Lung Disorder .
Chronic Bronchitis
Lung Disorder
Asthma
Asthma
Bronchitis, Chronic
Bronchoconstriction
Lung Diseases
Effectiveness
How Theochron Affects Patients
Theophylline is a drug that is chemically similar to caffeine and theobromine. It is used to relieve symptoms of asthma such as bronchospasm. Theophylline works in two ways: it relaxes the airways to make breathing easier, and also helps prevent the airways from becoming inflamed or irritated by external stimuli.
How Theochron works in the body
Theophylline works to open up airways and reduce airway sensitivity. This is done by blocking an enzyme that breaks down a chemical called cyclic AMP, which is responsible for tightening the airways. It also binds to adenosine receptors, preventing the airways from constricting. Finally, it stops inflammation genes from being activated, reducing inflammation in the airways.
When to interrupt dosage
The measure of Theochron is contingent upon the recognized affliction, including Bronchodilation, Bronchoconstriction and Chronic Obstructive Pulmonary Disease (COPD). The dosage fluctuates according to the technique of delivery showcased in the table below.
Condition
Dosage
Administration
Chronic Obstructive Pulmonary Disease
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Kit, Elixir, Elixir - Oral, Injection, solution - Intravenous, Capsule - Oral, Injection, Injection - Intravenous, Solution - Intravenous, Syrup, Syrup - Oral, Capsule
Asthma
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Kit, Elixir, Elixir - Oral, Injection, solution - Intravenous, Capsule - Oral, Injection, Injection - Intravenous, Solution - Intravenous, Syrup, Syrup - Oral, Capsule
Bronchitis, Chronic
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Kit, Elixir, Elixir - Oral, Injection, solution - Intravenous, Capsule - Oral, Injection, Injection - Intravenous, Solution - Intravenous, Syrup, Syrup - Oral, Capsule
Airway secretion clearance therapy
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Kit, Elixir, Elixir - Oral, Injection, solution - Intravenous, Capsule - Oral, Injection, Injection - Intravenous, Solution - Intravenous, Syrup, Syrup - Oral, Capsule
Acute Bronchitis
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Kit, Elixir, Elixir - Oral, Injection, solution - Intravenous, Capsule - Oral, Injection, Injection - Intravenous, Solution - Intravenous, Syrup, Syrup - Oral, Capsule
Bronchial Spasm
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Kit, Elixir, Elixir - Oral, Injection, solution - Intravenous, Capsule - Oral, Injection, Injection - Intravenous, Solution - Intravenous, Syrup, Syrup - Oral, Capsule
Emphysema
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Kit, Elixir, Elixir - Oral, Injection, solution - Intravenous, Capsule - Oral, Injection, Injection - Intravenous, Solution - Intravenous, Syrup, Syrup - Oral, Capsule
Bronchoconstriction
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Kit, Elixir, Elixir - Oral, Injection, solution - Intravenous, Capsule - Oral, Injection, Injection - Intravenous, Solution - Intravenous, Syrup, Syrup - Oral, Capsule
Lung Diseases
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Kit, Elixir, Elixir - Oral, Injection, solution - Intravenous, Capsule - Oral, Injection, Injection - Intravenous, Solution - Intravenous, Syrup, Syrup - Oral, Capsule
Bronchodilation
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Kit, Elixir, Elixir - Oral, Injection, solution - Intravenous, Capsule - Oral, Injection, Injection - Intravenous, Solution - Intravenous, Syrup, Syrup - Oral, Capsule
Bronchitis, Chronic
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Kit, Elixir, Elixir - Oral, Injection, solution - Intravenous, Capsule - Oral, Injection, Injection - Intravenous, Solution - Intravenous, Syrup, Syrup - Oral, Capsule
Warnings
There are 20 known major drug interactions with Theochron.
Common Theochron Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Theophylline.
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Theophylline.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Theophylline.
Bendamustine
Major
The metabolism of Bendamustine can be decreased when combined with Theophylline.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Theophylline.
Theochron Toxicity & Overdose Risk
Signs of an overdose on aripiprazole include seizures, abnormal heart rhythms, and gastrointestinal effects.
Theochron Novel Uses: Which Conditions Have a Clinical Trial Featuring Theochron?
280 active trials are currently analyzing the potential of Theochron to provide Bronchodilation, relief from Chronic Bronchitis and Asthma management.
Condition
Clinical Trials
Trial Phases
Chronic Obstructive Pulmonary Disease
68 Actively Recruiting
Phase 3, Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 4
Asthma
79 Actively Recruiting
Phase 1, Phase 4, Early Phase 1, Not Applicable, Phase 2, Phase 3
Airway secretion clearance therapy
0 Actively Recruiting
Bronchoconstriction
0 Actively Recruiting
Bronchodilation
0 Actively Recruiting
Emphysema
4 Actively Recruiting
Phase 2, Not Applicable
Bronchitis, Chronic
0 Actively Recruiting
Acute Bronchitis
1 Actively Recruiting
Not Applicable
Bronchitis, Chronic
0 Actively Recruiting
Lung Diseases
4 Actively Recruiting
Phase 1, Phase 2, Not Applicable
Bronchial Spasm
0 Actively Recruiting
Theochron Reviews: What are patients saying about Theochron?
4
Patient Review
10/7/2007
Theochron for Emphysema
Patient Q&A Section about theochron
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
What is the side effect of theophylline?
"You may experience some of the following side effects: nausea/vomiting, stomach/abdominal pain, headache, trouble sleeping, diarrhea, irritability, restlessness, nervousness, shaking, or increased urination."
Answered by AI
Is theophylline a steroid?
"Theophylline is a bronchodilator that helps to manage asthma by expanding airways. It is not a steroid medicine."
Answered by AI
Why is theophylline no longer used?
"Oral theophylline is not commonly used to treat chronic obstructive pulmonary disease (COPD) because it can cause undesirable side effects, especially at high doses. Newer drugs have been developed that are more effective and have fewer side effects."
Answered by AI