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What is Tessalon
BenzonatateThe Generic name of this drug
Treatment SummaryBenzonatate is a medication used to suppress cough in patients over 10 years old. It works by desensitizing the tissues in the lungs and pleura that trigger the cough reflex. Benzonatate was approved by the FDA in 1958 and is the only non-narcotic antitussive available by prescription. It has an anesthetic effect similar to drugs like procaine and tetracaine, which can cause severe toxicity and overdose if taken in large enough doses, particularly in children.
Tessalonis the brand name
Tessalon Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Tessalon
Benzonatate
1958
337
Approved as Treatment by the FDA
Benzonatate, also known as Tessalon, is approved by the FDA for 1 uses including Acute Bronchitis .Acute Bronchitis
Effectiveness
How Tessalon Affects PatientsBenzonatate is a drug used to reduce coughing caused by both short and long-term respiratory issues. It works by numbing the nerves in the lungs that are responsible for coughing. Studies have shown that it can decrease the number of coughs experienced, and its effects usually kick in after 15-20 minutes and last for 3-8 hours. Benzonatate does not affect the respiratory system in recommended doses.
How Tessalon works in the bodyBenzonatate is a local anesthetic that numbs nerve fibers in the respiratory system. These nerve fibers send signals to the brain when the lungs and airways are stretched, which in turn triggers a cough. By numbing these nerve fibers, benzonatate works to block this signal and stop coughing. It also works by blocking voltage-gated sodium channels in the body.
When to interrupt dosage
The measure of Tessalon is contingent upon the determined condition. The extent of dosage can be found in the table beneath, reliant upon the administration approach (e.g. Tablet or Capsule, liquid filled).Condition
Dosage
Administration
Acute Bronchitis
100.0 mg, , 200.0 mg, 150.0 mg
, Oral, Capsule, Capsule - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Warnings
Tessalon ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Benzonatate may interact with Pulse Frequency
Common Tessalon Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Minor
The serum concentration of Aclidinium can be increased when it is combined with Benzonatate.
Butyrylthiocholine
Minor
The serum concentration of Butyrylthiocholine can be increased when it is combined with Benzonatate.
Chloroprocaine
Minor
The serum concentration of Chloroprocaine can be increased when it is combined with Benzonatate.
Clevidipine
Minor
The serum concentration of Clevidipine can be increased when it is combined with Benzonatate.
Cocaine
Minor
The serum concentration of Cocaine can be increased when it is combined with Benzonatate.
Tessalon Toxicity & Overdose RiskThe toxic dose of benzonatate from taking it orally is 51mg/kg. Symptoms of an overdose usually start within 15-20 minutes and can affect the nervous and cardiovascular systems. In children, swallowing just one or two capsules can be fatal. Signs of overdose include restlessness, tremors, convulsions, coma, swelling in the brain, and cardiac arrest. It is important to empty the stomach and give activated charcoal to help reduce the effects of poisoning. For those with severe poisoning, breathing and kidney support may be needed. In some cases, intravenous fat emulsion therapy may be used to help with life-threatening
Tessalon Novel Uses: Which Conditions Have a Clinical Trial Featuring Tessalon?
8 active investigations are being conducted to assess the potential of Tessalon in treating Acute Bronchitis.Condition
Clinical Trials
Trial Phases
Acute Bronchitis
5 Actively Recruiting
Phase 4, Not Applicable, Early Phase 1
Tessalon Reviews: What are patients saying about Tessalon?
5Patient Review
7/30/2021 I had a cough for three days that got so bad I couldn't sleep. This medication stopped my coughing within 20 minutes and allowed me to get a good night's rest.
5Patient Review
3/27/2021 I am three months post-covid and have been having such intense coughing fits that I was getting nosebleeds. Just one day into this treatment, though, and I'm already feeling better.
5Patient Review
10/11/2021 This medication was a godsend. I had such severe coughing fits from COVID-19 that I genuinely thought I was going to die.
5Patient Review
9/6/2021 Tessalon perles have been a game-changer for me when it comes to colds and coughs. I can finally get some rest instead of being up all night coughing!
4.7Patient Review
8/18/2022 My first time using this medication was for a cough related to covid-19. It worked very well and I didn't have to use any cough syrup. Some people it doesn't work for, but that just means it's not the right medication for them.
Patient Q&A Section about tessalon
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Tessalon a narcotic?
"Benzonatate is a non-narcotic cough medicine that numbs the throat and lungs, making the cough reflex less active."
Answered by AI
Will Tessalon make me sleepy?
"If you experience any of the following side effects, you should discontinue use of the medication and seek medical help: severe drowsiness or dizziness, confusion, hallucinations."
Answered by AI
Is tessalon Perles the same as mucinex?
"Mucinex is a brand name for guaifenesin, which is an expectorant. It thins mucus, making it easier to cough up. Benzonatate is an antitussive that suppresses or quiets a cough. Brand names for Benzonatate include Tessalon."
Answered by AI
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