Tavist
Catarrh, Angioedema, Hives
Treatment
6 FDA approvals
2 Active Studies for Tavist
Treatment for
Catarrh
What is Tavist
Clemastine
The Generic name of this drug
Treatment Summary
Diphenhydramine is an antihistamine used to treat allergies, hay fever, and skin irritation. It is a first-generation drug that blocks the effects of histamine in the body and can cause drowsiness as a side effect.
Clemastine Fumarate
is the brand name
Tavist Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Clemastine Fumarate
Clemastine
1992
26
Approved as Treatment by the FDA
Clemastine, also known as Clemastine Fumarate, is approved by the FDA for 6 uses including Allergic Rhinitis (AR) and Hives .
Allergic Rhinitis (AR)
Used to treat Allergic Rhinitis (AR) in combination with Phenylpropanolamine
Hives
Urticaria
Angioedema
Catarrh
Angioedema
Effectiveness
How Tavist Affects Patients
Clemastine is an antihistamine which also has anticholinergic and sedative effects. It works by blocking the effects of histamine, a substance produced by the body when it reacts to an allergen. Depending on the dose, this drug can have stimulating or calming effects on the central nervous system. It also causes dry mouth and other anticholinergic effects. Clemastine does not stop the body from producing histamine, but instead blocks its effects from occurring.
How Tavist works in the body
Clemastine blocks the effects of histamine, a molecule in your body that causes symptoms of allergies. By blocking the histamine, Clemastine helps relieve those symptoms.
When to interrupt dosage
The amount of Tavist is contingent upon the determined affliction, including Hay Fever, Hives and Catarrh. The dosage fluctuates as per the method of administration mentioned in the table below.
Condition
Dosage
Administration
Catarrh
1.34 mg, , 2.68 mg, 0.5 mg/mL, 1.0 mg, 0.67 mg/mL
, Tablet, Tablet - Oral, Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral
Angioedema
1.34 mg, , 2.68 mg, 0.5 mg/mL, 1.0 mg, 0.67 mg/mL
, Tablet, Tablet - Oral, Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral
Hives
1.34 mg, , 2.68 mg, 0.5 mg/mL, 1.0 mg, 0.67 mg/mL
, Tablet, Tablet - Oral, Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral
Warnings
Tavist has two contraindications and should not be employed when encountering the conditions in the following table.
Tavist Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
treating lower respiratory tract symptoms
Do Not Combine
There are 20 known major drug interactions with Tavist.
Common Tavist Drug Interactions
Drug Name
Risk Level
Description
Amiodarone
Major
The risk or severity of QTc prolongation can be increased when Clemastine is combined with Amiodarone.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Clemastine.
Arsenic trioxide
Major
The risk or severity of QTc prolongation can be increased when Clemastine is combined with Arsenic trioxide.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Clemastine is combined with Artemether.
Asenapine
Major
The risk or severity of QTc prolongation can be increased when Clemastine is combined with Asenapine.
Tavist Toxicity & Overdose Risk
The toxic dose of antihistamines in rats is 3550 mg/kg and in mice is 730 mg/kg. If someone takes too much antihistamines, they may experience different reactions, including feeling drowsy to passing out. In children, the reaction is usually more intense and can include excitement, hallucinations, difficulty with coordination, muscle twitching, fever, blue skin, convulsions, and tremors, followed by tiredness and difficulty breathing. In adults, they are more likely to feel sleepy or pass out. Other common symptoms include a dry mouth, wide open pupils, a flushed face, and a fever.
Tavist Novel Uses: Which Conditions Have a Clinical Trial Featuring Tavist?
39 active studies are currently underway to investigate the potential of Tavist in relieving symptoms of Hay Fever, Catarrh and Angioedema.
Condition
Clinical Trials
Trial Phases
Angioedema
2 Actively Recruiting
Phase 4, Phase 1, Phase 2
Hives
0 Actively Recruiting
Catarrh
0 Actively Recruiting
Patient Q&A Section about tavist
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Is Tavist still available?
"is the last day that the Tavist Allergy brand name will be in use in the United States. If the FDA has approved any generic equivalents to this product, they will be available as of that date."
Answered by AI
What is the generic for Tavist?
"The generic name for the oral medication Clemastine is Klemastine."
Answered by AI
Is clemastine available over the counter?
"The medication is used to treat the symptoms of a runny nose, watery eyes, and itching of the nose or throat.
Clemastine fumarate is an antihistamine that is available over the counter. The medication is used to relieve symptoms such as a runny nose, watery eyes, and itching of the nose or throat."
Answered by AI
Does Tavist make you sleepy?
"These are some of the possible side effects of the medication, however they may lessen as your body gets used to the medication."
Answered by AI