Tavist

Catarrh, Angioedema, Hives

Treatment

6 FDA approvals

2 Active Studies for Tavist

Treatment for

Catarrh

What is Tavist

ClemastineThe Generic name of this drug

Treatment SummaryDiphenhydramine is an antihistamine used to treat allergies, hay fever, and skin irritation. It is a first-generation drug that blocks the effects of histamine in the body and can cause drowsiness as a side effect.

Clemastine Fumarateis the brand name

Tavist Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Clemastine Fumarate

Clemastine

1992

Approved as Treatment by the FDA

Clemastine, also known as Clemastine Fumarate, is approved by the FDA for 6 uses including Hives and Allergic Rhinitis (AR) .

Hives

Allergic Rhinitis (AR)

Used to treat Allergic Rhinitis (AR) in combination with Phenylpropanolamine

Urticaria

Angioedema

Catarrh

Angioedema

Effectiveness

How Tavist Affects PatientsClemastine is an antihistamine which also has anticholinergic and sedative effects. It works by blocking the effects of histamine, a substance produced by the body when it reacts to an allergen. Depending on the dose, this drug can have stimulating or calming effects on the central nervous system. It also causes dry mouth and other anticholinergic effects. Clemastine does not stop the body from producing histamine, but instead blocks its effects from occurring.

How Tavist works in the bodyClemastine blocks the effects of histamine, a molecule in your body that causes symptoms of allergies. By blocking the histamine, Clemastine helps relieve those symptoms.

When to interrupt dosage

The amount of Tavist is contingent upon the determined affliction, including Hay Fever, Hives and Catarrh. The dosage fluctuates as per the method of administration mentioned in the table below.

Condition

Dosage

Administration

Catarrh

1.34 mg, , 2.68 mg, 0.5 mg/mL, 1.0 mg, 0.67 mg/mL

, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral

Angioedema

1.34 mg, , 2.68 mg, 0.5 mg/mL, 1.0 mg, 0.67 mg/mL

, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral

Hives

1.34 mg, , 2.68 mg, 0.5 mg/mL, 1.0 mg, 0.67 mg/mL

, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral

Warnings

Tavist has two contraindications and should not be employed when encountering the conditions in the following table.Tavist Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

treating lower respiratory tract symptoms

Do Not Combine

There are 20 known major drug interactions with Tavist.

Common Tavist Drug Interactions

Drug Name

Risk Level

Description

Amiodarone

Major

The risk or severity of QTc prolongation can be increased when Clemastine is combined with Amiodarone.

Amoxapine

Major

The metabolism of Amoxapine can be decreased when combined with Clemastine.

Arsenic trioxide

Major

The risk or severity of QTc prolongation can be increased when Clemastine is combined with Arsenic trioxide.

Artemether

Major

The risk or severity of QTc prolongation can be increased when Clemastine is combined with Artemether.

Asenapine

Major

The risk or severity of QTc prolongation can be increased when Clemastine is combined with Asenapine.

Tavist Toxicity & Overdose RiskThe toxic dose of antihistamines in rats is 3550 mg/kg and in mice is 730 mg/kg. If someone takes too much antihistamines, they may experience different reactions, including feeling drowsy to passing out. In children, the reaction is usually more intense and can include excitement, hallucinations, difficulty with coordination, muscle twitching, fever, blue skin, convulsions, and tremors, followed by tiredness and difficulty breathing. In adults, they are more likely to feel sleepy or pass out. Other common symptoms include a dry mouth, wide open pupils, a flushed face, and a fever.

Tavist Novel Uses: Which Conditions Have a Clinical Trial Featuring Tavist?

39 active studies are currently underway to investigate the potential of Tavist in relieving symptoms of Hay Fever, Catarrh and Angioedema.

Condition

Clinical Trials

Trial Phases

Angioedema

2 Actively Recruiting

Phase 2, Phase 4

Hives

1 Actively Recruiting

Phase 2

Catarrh

0 Actively Recruiting

Patient Q&A Section about tavist

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Tavist still available?

"is the last day that the Tavist Allergy brand name will be in use in the United States. If the FDA has approved any generic equivalents to this product, they will be available as of that date."

Answered by AI

What is the generic for Tavist?

"The generic name for the oral medication Clemastine is Klemastine."

Answered by AI

Is clemastine available over the counter?

"The medication is used to treat the symptoms of a runny nose, watery eyes, and itching of the nose or throat.

Clemastine fumarate is an antihistamine that is available over the counter. The medication is used to relieve symptoms such as a runny nose, watery eyes, and itching of the nose or throat."

Answered by AI