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What is Steglatro
ErtugliflozinThe Generic name of this drug
Treatment SummaryErtugliflozin is a medication used to treat type 2 diabetes. It works by blocking a protein in the body that helps to reabsorb glucose from the kidneys. This drug was approved by the FDA in 2017 and is available as a standalone treatment or in combination with other diabetes medications such as sitagliptin or metformin hydrochloride.
Steglatrois the brand name
Steglatro Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Steglatro
Ertugliflozin
2017
13
Approved as Treatment by the FDA
Ertugliflozin, also known as Steglatro, is approved by the FDA for 3 uses like Physical Activity and Diet .Physical Activity
Used in combination with other therapies
Diet
Used in combination with other therapies
Type 2 Diabetes
Used in combination with other therapies
Effectiveness
How Steglatro Affects PatientsErtugliflozin works by causing the body to excrete more glucose in the urine. This results in a negative balance and increased urination. As a result, this diabetes drug has been found to help lower body weight and blood pressure in those with diabetes.
How Steglatro works in the bodyErtugliflozin helps to reduce blood sugar levels by blocking a protein that normally reabsorbs glucose from the urine. This causes more glucose to be excreted in the urine, which lowers the amount of glucose in the blood. As a result, it reduces hyperglycemia without needing to produce more insulin.
When to interrupt dosage
The suggested dose of Steglatro is contingent upon the diagnosed affliction, including Type 2 Diabetes, Diet and Physical Activity. The magnitude of dosage varies, in line with the administration technique (e.g. Tablet, film coated - Oral or Oral) indicated in the table below.Condition
Dosage
Administration
Physical Activity
, 5.0 mg, 15.0 mg, 2.5 mg, 7.5 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet - Oral, Tablet
Diet
, 5.0 mg, 15.0 mg, 2.5 mg, 7.5 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet - Oral, Tablet
Type 2 Diabetes
, 5.0 mg, 15.0 mg, 2.5 mg, 7.5 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet - Oral, Tablet
Warnings
Steglatro has two contraindications and should not be incorporated with the disorders listed in the following table.Steglatro ContraindicationsCondition
Risk Level
Notes
Dialysis therapy
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Ertugliflozin may interact with Pulse Frequency
Common Steglatro Drug Interactions
Drug Name
Risk Level
Description
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Ertugliflozin.
Belinostat
Major
The metabolism of Belinostat can be decreased when combined with Ertugliflozin.
Binimetinib
Major
The metabolism of Binimetinib can be decreased when combined with Ertugliflozin.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Ertugliflozin.
Etoposide
Major
The metabolism of Etoposide can be decreased when combined with Ertugliflozin.
Steglatro Toxicity & Overdose RiskErtugliflozin has been found to be generally safe, with few reported side effects. However, there has been an increased incidence of adrenal medullary pheochromocytoma, which may be caused by the drug's effects on calcium levels. There have been no reports of mutagenic activity or fertility problems associated with use of the drug.
Steglatro Novel Uses: Which Conditions Have a Clinical Trial Featuring Steglatro?
196 active clinical trials are currently being conducted to assess the effectiveness of Steglatro in managing Type 2 Diabetes, Physical Activity and Dietary modifications.Condition
Clinical Trials
Trial Phases
Type 2 Diabetes
192 Actively Recruiting
Phase 2, Not Applicable, Early Phase 1, Phase 1, Phase 4, Phase 3
Diet
5 Actively Recruiting
Not Applicable
Physical Activity
39 Actively Recruiting
Not Applicable, Phase 2, Phase 1, Early Phase 1
Steglatro Reviews: What are patients saying about Steglatro?
4Patient Review
3/16/2019 This drug has already lowered my sugar levels by 50 points and I've only just started using it. If it keeps up this good work, it'll be a great help to me.
3Patient Review
5/7/2020 I've been on steglatro for just over two weeks now, and I'm not seeing the results I'd hoped for. My sugar hasn't dropped much, which is concerning. Additionally, I've developed a pain in my neck that's worrying me. Not sure if I'll continue with this medication or not.
2.3Patient Review
2/3/2019 I started using this medication four months ago and saw great results the first month. However, since then I've been dealing with vaginal itchiness and a yeast infection that won't go away no matter what medicine I take. Additionally, I've had problems with constipation. Overall, it's not worth it to me and I'm going back to my previous medication.
1.7Patient Review
8/21/2018 I got a nasty yeast infection within a week of starting to take this medication. My blood sugar levels didn't improve either. I can only hope that it works better for other people than it did for me.
1.7Patient Review
10/1/2019 I had some really unpleasant side effects after taking this medication for just two weeks. I'm glad I stopped when I did, and it seems like the symptoms have mostly dissipated now.
1Patient Review
12/14/2021 This drug unfortunately caused me a lot of dehydration and an increased heart rate.
1Patient Review
1/29/2022 I experienced literally every single side effect this treatment came with, and it didn't even help lower my sugar levels. I'm really struggling, but my doctor called me this morning to check in. She was very understanding and called in a new prescription for me that should be more effective.
Patient Q&A Section about steglatro
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is metformin a Steglatro?
"SEGLUROMET is a prescription medicine that contains 2 drugs - ertugliflozin (STEGLATRO ®) and metformin hydrochloride. It is used to improve blood sugar levels in adults with type 2 diabetes, when used with diet and exercise."
Answered by AI
What side effects does Steglatro have?
"The side effects of Steglatro may include: back pain, headache, increased thirst, producing more urine or needing to urinate more often than usual, stuffy or runny nose, urinary tract infection (UTI), vaginal itchiness, weight loss."
Answered by AI
Are Jardiance and Steglatro the same?
"No, Steglatro is not the same as Jardiance. However, they are very similar drugs. They both belong to the drug class sodium glucose cotransporter 2 (SGLT2) inhibitors. Steglatro contains ertugliflozin as the active drug while Jardiance contains empagliflozin."
Answered by AI
What is the drug Steglatro used for?
"STEGLATRO is a prescription pill used in adults with type 2 diabetes to improve blood sugar (glucose) control along with diet and exercise. STEGLATRO is not for people with type 1 diabetes as it may increase the risk of diabetic ketoacidosis in these people."
Answered by AI