Seromycin
Tuberculosis, organism demonstrated to be susceptible, Disease + 3 more
Treatment
4 FDA approvals
0 Active Studies for Seromycin
Treatment for
Tuberculosis
What is Seromycin
Cycloserine
The Generic name of this drug
Treatment Summary
Antibiotic medication produced by a type of bacteria called Streptomyces garyphalus.
Cycloserine
is the brand name
Seromycin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Cycloserine
Cycloserine
1952
7
Approved as Treatment by the FDA
Cycloserine, otherwise called Cycloserine, is approved by the FDA for 4 uses such as Pulmonary Tuberculosis (TB) and Tuberculosis .
Pulmonary Tuberculosis (TB)
Used to treat Pulmonary Tuberculosis (TB) in combination with null
Tuberculosis
Used to treat Tuberculosis, Extrapulmonary in combination with null
Tuberculosis
Used to treat Pulmonary Tuberculosis (TB) in combination with null
Disease
Used to treat inadequate response to conventional therapy in combination with null
Effectiveness
How Seromycin Affects Patients
Cycloserine is a broad-spectrum antibiotic that can kill or slow the growth of bacteria. It works by blocking the formation of peptidoglycans, which are the building blocks of a bacterial cell wall. When these walls become weakened by cycloserine, the bacteria can die.
How Seromycin works in the body
Cycloserine works to stop bacteria from growing by blocking an important step in the formation of their cell walls. It does this by preventing two enzymes from converting a certain amino acid into the chemical needed to make up the cell wall.
When to interrupt dosage
The dosage of Seromycin is contingent upon the identified issue, such as organism demonstrated to be susceptible, inadequate response to traditional treatment and Failed traditional therapy. The amount of dosage can be found in the table below, depending on the route of administration.
Condition
Dosage
Administration
Urinary tract infection
, 2.5 mg/mg, 250.0 mg
Oral, Capsule, , Capsule - Oral
Tuberculosis
, 2.5 mg/mg, 250.0 mg
Oral, Capsule, , Capsule - Oral
organism demonstrated to be susceptible
, 2.5 mg/mg, 250.0 mg
Oral, Capsule, , Capsule - Oral
Disease
, 2.5 mg/mg, 250.0 mg
Oral, Capsule, , Capsule - Oral
Failed conventional therapy
, 2.5 mg/mg, 250.0 mg
Oral, Capsule, , Capsule - Oral
Tuberculosis
, 2.5 mg/mg, 250.0 mg
Oral, Capsule, , Capsule - Oral
Warnings
Seromycin Contraindications
Condition
Risk Level
Notes
Schizophrenia
Do Not Combine
ethanol
Do Not Combine
Depression
Do Not Combine
Kidney Failure
Do Not Combine
Anxiety
Do Not Combine
Epilepsy
Do Not Combine
There are 20 known major drug interactions with Seromycin.
Common Seromycin Drug Interactions
Drug Name
Risk Level
Description
Bacillus calmette-guerin substrain russian BCG-I live antigen
Major
The therapeutic efficacy of Bacillus calmette-guerin substrain russian BCG-I live antigen can be decreased when used in combination with Cycloserine.
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Cycloserine.
Acepromazine
Minor
Cycloserine may increase the neurotoxic activities of Acepromazine.
Aceprometazine
Minor
Cycloserine may increase the neurotoxic activities of Aceprometazine.
Acetophenazine
Minor
Cycloserine may increase the neurotoxic activities of Acetophenazine.
Seromycin Toxicity & Overdose Risk
The most toxic dose of cycloserine for mice has been found to be 5290mg/kg and for rats it is over 5000mg/kg. Overdosing on cycloserine can cause drowsiness, confusion, headache, dizziness, irritability, a feeling of numbness or tingling in the skin, difficulty speaking, paralysis, abnormal behavior, seizures, and loss of consciousness.
Seromycin Novel Uses: Which Conditions Have a Clinical Trial Featuring Seromycin?
An ongoing inquiry is assessing the effectiveness of Seromycin for Failed conventional therapy, Tuberculosis, Extrapulmonary and organisms shown to be vulnerable.
Condition
Clinical Trials
Trial Phases
Urinary tract infection
0 Actively Recruiting
Tuberculosis
0 Actively Recruiting
Failed conventional therapy
0 Actively Recruiting
Tuberculosis
0 Actively Recruiting
organism demonstrated to be susceptible
0 Actively Recruiting
Disease
0 Actively Recruiting
Seromycin Reviews: What are patients saying about Seromycin?
3
Patient Review
2/4/2011
Seromycin for Osteoporosis
3
Patient Review
2/1/2011
Seromycin for Osteoporosis
3
Patient Review
2/1/2011
Seromycin for Osteoporosis
3
Patient Review
2/4/2011
Seromycin for Osteoporosis
3
Patient Review
2/3/2011
Seromycin for Osteoporosis
3
Patient Review
2/4/2011
Seromycin for Osteoporosis
3
Patient Review
2/3/2011
Seromycin for Osteoporosis
3
Patient Review
2/1/2011
Seromycin for Osteoporosis
3
Patient Review
2/1/2011
Seromycin for Osteoporosis
Patient Q&A Section about seromycin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
What drug class is seromycin?
"Amino acids are organic compounds that have both an amino and carboxylic acid functional group, as well as a side chain that is specific to each amino acid."
Answered by AI
How is cycloserine administered?
"Doses are then increased to 500 mg twice daily for the next 2 weeks as tolerated. After 4 weeks, the dosage is adjusted according to the therapeutic response.
Seromycin can be taken orally and the current dosage suggestion is 500 mg to 1 g per day, divided into monitored doses through blood levels. The usual starting dose for adults is 250 mg, taken twice a day at 12 hour intervals, for the first 2 weeks. After that, the dosage is increased to 500 mg twice a day for the next 2 weeks if tolerated. After 4 weeks, the dosage is then adjusted according to response to the medication."
Answered by AI
What type of antibiotic is cycloserine?
"Cycloserine is a broad-spectrum antibiotic and has activity against Gram-positive and Gram-negative bacteria.
Cycloserine, trade-named Seromycin, is an antibiotic that also inhibits GABA transaminase. It is effective against Gram-positive and Gram-negative bacteria, and is prescribed as part of a regimen to treat active drug-resistant tuberculosis."
Answered by AI
What is cycloserine used for?
"Cycloserine belongs to the class of antibiotics known as bacteriostatics, and is used to treat tuberculosis. When used to treat TB, it is given in conjunction with other medications. Cycloserine may also be used to treat other conditions at the discretion of a medical practitioner."
Answered by AI