Quinaretic

Heart Attack, Congestive Heart Failure, Diabetic Nephropathies + 2 more
Treatment
3 FDA approvals
20 Active Studies for Quinaretic

What is Quinaretic

QuinaprilThe Generic name of this drug
Treatment SummaryHydrochlorothiazide is a diuretic drug used to treat swelling and high blood pressure. It is the most commonly prescribed thiazide diuretic, but its usage is decreasing in favor of other medications such as angiotensin converting enzyme inhibitors and angiotensin II receptor blockers. Combination products containing Hydrochlorothiazide and these other drugs are available. The FDA approved Hydrochlorothiazide in 1959.
Quinapril Hydrochlorideis the brand name
Quinaretic Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Quinapril Hydrochloride
Quinapril
1991
190

Approved as Treatment by the FDA

Quinapril, also known as Quinapril Hydrochloride, is approved by the FDA for 3 uses including Congestive Heart Failure (CHF) and Hypertensive disease .
Congestive Heart Failure (CHF)
Used in combination with other therapies
Hypertensive disease
Helps manage High Blood Pressure (Hypertension)
Congestive Heart Failure
Used in combination with other therapies

Effectiveness

How Quinaretic Affects PatientsHydrochlorothiazide helps to stop your body from absorbing too much salt and water, which leads to more water being excreted in your urine. The amount of hydrochlorothiazide you are prescribed depends on your individual needs, but typically ranges between 25-100mg. People with reduced kidney or liver function should use this drug with caution.
How Quinaretic works in the bodyHydrochlorothiazide works to reduce water reabsorption in the kidneys. It is transported into the cells of the distal convoluted tubule by proteins called organic anion transporters. Normally, cells in the distal convoluted tubule absorb sodium and push it into the surrounding area, which creates a concentration gradient and pulls more water into the cells. Hydrochlorothiazide stops this from happening by inhibiting the sodium-chloride symporter, which prevents sodium from being absorbed and reduces the amount of water that is pulled in.

When to interrupt dosage

The prescribed amount of Quinaretic is contingent upon the diagnosed illness, like Antepartum magnesium sulfate prophylaxis, blood pressure inadequately administered with monotherapy and antihypertensives. The dosage varies, in concurrence with the administration procedure (e.g. Tablet, coated - Oral or Oral) featured in the following table.
Condition
Dosage
Administration
Heart Attack
, 5.0 mg, 10.0 mg, 20.0 mg, 40.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Ventricular Dysfunction, Left
, 5.0 mg, 10.0 mg, 20.0 mg, 40.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Diabetic Nephropathies
, 5.0 mg, 10.0 mg, 20.0 mg, 40.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Hypertensive disease
, 5.0 mg, 10.0 mg, 20.0 mg, 40.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Congestive Heart Failure
, 5.0 mg, 10.0 mg, 20.0 mg, 40.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral

Warnings

Quinaretic has two contraindications, and its usage should not be pursued when experiencing any of the conditions in the following table.Quinaretic Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Angioedema
Do Not Combine
There are 20 known major drug interactions with Quinaretic.
Common Quinaretic Drug Interactions
Drug Name
Risk Level
Description
Amifostine
Major
Quinapril may increase the hypotensive activities of Amifostine.
Azathioprine
Major
The risk or severity of myelosuppression, anemia, and severe leukopenia can be increased when Quinapril is combined with Azathioprine.
Lithium carbonate
Major
The serum concentration of Lithium carbonate can be increased when it is combined with Quinapril.
Lithium citrate
Major
The serum concentration of Lithium citrate can be increased when it is combined with Quinapril.
Lithium hydroxide
Major
The serum concentration of Lithium hydroxide can be increased when it is combined with Quinapril.
Quinaretic Toxicity & Overdose RiskThe toxic dose of hydrochlorothiazide in mice and rats is over 10g/kg. Those who overdose on this drug may experience low levels of potassium, chlorine, and sodium. Treatment includes fluids and electrolytes, as well as medications to increase blood pressure and oxygen therapy if needed.

Quinaretic Novel Uses: Which Conditions Have a Clinical Trial Featuring Quinaretic?

158 active trials are currently examining the potential of Quinaretic to alleviate Cirrhosis, Edema and Congestive Heart Failure.
Condition
Clinical Trials
Trial Phases
Congestive Heart Failure
12 Actively Recruiting
Not Applicable, Phase 1, Phase 2
Ventricular Dysfunction, Left
0 Actively Recruiting
Diabetic Nephropathies
0 Actively Recruiting
Heart Attack
26 Actively Recruiting
Not Applicable, Phase 4, Phase 1, Phase 2, Early Phase 1, Phase 3
Hypertensive disease
22 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3

Patient Q&A Section about quinaretic

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

When do you drink ADCO retic?

"This medication works best if it is taken at least four hours before bedtime. The appropriate dosage is based on the patient's medical condition and response to treatment. To get the most benefit from the medication, it should be taken at the same time each day."

Answered by AI

What is amiloride HCl used for?

"Amiloride is a diuretic that helps your body keep potassium and prevents blood pressure from becoming too low. It is available only with a doctor's prescription."

Answered by AI

What is the side effect of adcodol?

"The following text lists some general and specific disorders along with the frequency with which they occur. General disorders such as drowsiness, sweating and facial flushing, and hypothermia occur in a significant percentage of patients. Gastrointestinal disorders such as constipation, nausea, vomiting and dry mouth occur in a minority of patients. Nervous system disorders such as restlessness, vertigo and raised intracranial pressure are relatively uncommon. Psychiatric disorders such as confusion and mood changes are rare."

Answered by AI

What type of drug is Accuretic?

"Accuretic is an effective 2-in-1 blood pressure medicine that also protects kidney function in the long term. It is a convenient single pill that combines two first-choice drugs for high blood pressure."

Answered by AI

Clinical Trials for Quinaretic

Have you considered Quinaretic clinical trials? We made a collection of clinical trials featuring Quinaretic, we think they might fit your search criteria.
Have you considered Quinaretic clinical trials? We made a collection of clinical trials featuring Quinaretic, we think they might fit your search criteria.
Have you considered Quinaretic clinical trials? We made a collection of clinical trials featuring Quinaretic, we think they might fit your search criteria.
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