Your session is about to expire
← Back to Search
Mineral Supplement
Magnesium Supplementation for High Blood Pressure
N/A
Recruiting
Research Sponsored by Brigham and Women's Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Total magnesium intake from supplements of no more than 100 mg/day
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and 12 week
Awards & highlights
Study Summary
This trial examines if taking 480mg of magnesium daily for 12 weeks can lower blood pressure.
Who is the study for?
This trial is for adults with a self-reported systolic blood pressure between 125-159 mmHg and measured seated systolic blood pressure of 130-159 mmHg. Participants should have a BMI under 40, take no more than 100 mg/day of magnesium from supplements, and be willing to keep their diet the same during the study. People with severe high blood pressure, certain chronic diseases, or those who are pregnant or planning to move away can't join.Check my eligibility
What is being tested?
The trial is testing if taking a daily dose of magnesium glycinate (480 mg) for three months can lower high systolic blood pressure compared to a placebo. The participants will either receive the supplement or an inactive pill without knowing which one they're getting.See study design
What are the potential side effects?
Magnesium supplements may cause digestive issues like diarrhea or stomach cramps in some people. High doses might lead to more serious problems such as irregular heartbeat but this is rare especially at controlled doses.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I take 100 mg or less of magnesium supplements daily.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline and 12 week
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and 12 week
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Change in seated diastolic blood pressure from baseline to 12 weeks
Change in seated systolic blood pressure from baseline to 12 weeks
Secondary outcome measures
Change in RBC magnesium levels from baseline to 12 weeks
Change in serum magnesium levels from baseline to 12 weeks
Whether the effect of magnesium on seated blood pressure is modified by baseline serum and/or RBC magnesium
Trial Design
2Treatment groups
Active Control
Placebo Group
Group I: magnesiumActive Control1 Intervention
magnesium glycinate supplement, 480 mg/day
Group II: placeboPlacebo Group1 Intervention
placebo supplement
Find a Location
Who is running the clinical trial?
Brigham and Women's HospitalLead Sponsor
1,610 Previous Clinical Trials
11,470,239 Total Patients Enrolled
Pure EncapsulationsIndustry Sponsor
1 Previous Clinical Trials
59 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I have not had any cancer, except for non-melanoma skin cancer, in the last 5 years.I have a history of kidney disease.I have had kidney failure in the past.I have used antacids or laxatives 4 or more times a week in the last 3 months.Your blood pressure is between 130 and 159 when you are sitting down.I have been on dialysis.I cannot or do not want to swallow 4 pills daily.I have a history of heart disease, including heart attack, stroke, or procedures to improve blood flow to my heart.You have a systolic blood pressure reading between 125 and 159 mmHg when you measure it yourself.Your blood pressure is 100 mmHg or higher when measured while sitting down.I have a history of inflammatory bowel disease.You have a history of having too much magnesium in your blood.I am not pregnant, nursing, or planning to become pregnant during treatment.I have a history of diabetes (type 1 or 2).Your body mass index (BMI) is less than 40.I have had pancreatitis before.I take 100 mg or less of magnesium supplements daily.
Research Study Groups:
This trial has the following groups:- Group 1: magnesium
- Group 2: placebo
Awards:
This trial has 0 awards, including:Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are senior citizens included in the parameters of this investigation?
"The accepted age range for this clinical trial is from 30 to 74 years old."
Answered by AI
Is enrollment in this research project an option available to me?
"This study is open to 120 patients aged 30-74 with a self-reported systolic blood pressure between 125-139 mmHg, measured seated systolic blood pressure of 130-154 mmHg at screening visit, body mass index below 40 kg/m2 and total magnesium intake from supplements not exceeding 100 mg/day. The 12 week intervention also requires participants maintain their diet and supplement use patterns during the treatment period."
Answered by AI
How many participants are there in this clinical experiment?
"Affirmative. According to the clinicaltrials.gov portal, this particular medical study is presently seeking participants; it was first published on January 17th 2023 and updated most recently on February 1st 2023. The trial requires a total of 120 patients from one site for completion."
Answered by AI
Are there any remaining openings for participants in this research project?
"Affirmative. Clinicaltrials.gov supports the claim that this scientific research, initially posted on January 17th 2023, is currently enrolling participants. Approximately 120 individuals need to be enrolled between 1 clinic within the study's timeframe."
Answered by AI
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger