Qnasl

Cellulitis, Asthma, Nasal Polyps + 10 more

Treatment

20 Active Studies for Qnasl

Treatment for

Cellulitis

What is Qnasl

Beclomethasone dipropionate

The Generic name of this drug

Treatment Summary

Beclomethasone dipropionate is a type of steroid medication used to treat inflammatory conditions such as asthma, allergic rhinitis, and certain skin conditions. It is available in several forms such as an inhaler, nasal spray, and topical cream. Beclomethasone dipropionate works by reducing inflammation, itching, and other allergy symptoms. Compared to other types of corticosteroids, beclomethasone dipropionate is less irritating to the nasal mucosa and works for a longer period of time.

Beconase AQ

is the brand name

image of different drug pills on a surface

Qnasl Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Beconase AQ

Beclomethasone dipropionate

1989

Effectiveness

How Qnasl Affects Patients

Beclomethasone dipropionate is a drug used to treat inflammatory diseases like asthma, allergic rhinitis, and certain skin conditions. It works by decreasing the activity of inflammatory cells which helps reduce pain, swelling, and other symptoms of inflammation. When inhaled, it can also help improve lung function and relieve asthma symptoms. However, long-term use of this drug can lead to suppressed immune function, growth suppression in children, and disruption of the hypothalamo-pituitary-adrenal (HPA) axis. It can also increase the risk of developing infections like candida albicans of the mouth and

How Qnasl works in the body

Beclomethasone dipropionate is a corticosteroid that is active once it enters the body and binds to the glucocorticoid receptor. This binds to genes that switch on anti-inflammatory proteins, like lipocortin-1 and interleukin-10, while also blocking pro-inflammatory genes like cytokines and adhesion molecules. This works by preventing transcription factors, like nuclear factor-kappa B, from accessing their binding sites. As a result, the inflammation process is dampened.

When to interrupt dosage

The proposed dosage of Qnasl is contingent upon the specified condition, including Adrenal Cortex Hormones, Dermatosis and Nasal Polyps. The amount of dosage fluctuates, based on the administration technique (e.g. Aerosol, metered; Suspension - Nasal or Powder - Respiratory (inhalation)) detailed in the table beneath.

Condition

Dosage

Administration

Cellulitis

, 0.042 mg, 0.04 mg, 0.08 mg, 0.1 mg, 0.2 mg, 0.025 %, 0.25 mg/mL, 0.087 mg, 0.172 mg, 0.088 mg, 0.25 mg/pump actuation, 0.1 mg/pump actuation, 0.05 mg/pump actuation, 0.04 mg/pump actuation, 0.08 mg/pump actuation

, Spray, suspension, Nasal, Spray, suspension - Nasal, Aerosol, metered - Respiratory (inhalation), Respiratory (inhalation), Aerosol, metered, Powder, Powder - Respiratory (inhalation), Topical, Cream - Topical, Cream, Aerosol, metered - Nasal, Aerosol, metered; Suspension, Aerosol, metered; Suspension - Nasal, Nasal; Respiratory (inhalation), Aerosol, metered - Nasal; Respiratory (inhalation), Suspension, Suspension - Nasal, Lotion - Topical, Lotion, Capsule - Respiratory (inhalation), Capsule, Spray - Nasal, Spray

Asthma

Nasal Polyps

Operation on nose

Dermatosis

Skin Diseases

corticosteroid responsive

Hay Fever

Sinusitis

Rhinitis, Allergic

Sinusitis

Rhinitis, Vasomotor

Warnings

Qnasl has six contraindications; therefore, it should be avoided while encountering any of the conditions presented in the table below.

Qnasl Contraindications

Condition

Risk Level

Notes

Cellulitis

Do Not Combine

Tuberculosis

Do Not Combine

Status Asthmaticus

Do Not Combine

infected skin lesions

Do Not Combine

Virus Diseases

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Beclomethasone Dipropionate may interact with Pulse Frequency

There are 20 known major drug interactions with Qnasl.

Common Qnasl Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Beclomethasone dipropionate is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Beclomethasone dipropionate is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abatacept

Major

The risk or severity of adverse effects can be increased when Beclomethasone dipropionate is combined with Abatacept.

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Beclomethasone dipropionate.

Abetimus

Major

The risk or severity of adverse effects can be increased when Beclomethasone dipropionate is combined with Abetimus.

Qnasl Toxicity & Overdose Risk

The lowest toxic dose of beclometasone dipropionate in rats is greater than 3750mg/kg. In general, this drug has low acute toxicity. However, taking in large amounts of the drug over a short period of time can reduce the activity of the HPA axis. Taking too much of this drug for a long time may also cause adrenal suppression.

image of a doctor in a lab doing drug, clinical research

Qnasl Novel Uses: Which Conditions Have a Clinical Trial Featuring Qnasl?

252 active clinical trials are in progress to evaluate the potential of Qnasl in providing relief from corticosteroid-responsive dermatoses, Chronic Obstructive Pulmonary Disease (COPD) and Perennial Allergic Rhinitis (PAR).

Condition

Clinical Trials

Trial Phases

Asthma

87 Actively Recruiting

Phase 1, Phase 4, Early Phase 1, Not Applicable, Phase 2, Phase 3

Skin Diseases

0 Actively Recruiting

Nasal Polyps

4 Actively Recruiting

Not Applicable, Phase 4

corticosteroid responsive

0 Actively Recruiting

Hay Fever

0 Actively Recruiting

Sinusitis

0 Actively Recruiting

Cellulitis

0 Actively Recruiting

Rhinitis, Allergic

0 Actively Recruiting

Operation on nose

0 Actively Recruiting

Dermatosis

0 Actively Recruiting

Rhinitis, Vasomotor

1 Actively Recruiting

Not Applicable

Sinusitis

4 Actively Recruiting

Early Phase 1, Phase 1, Phase 2

Nasal Polyps

0 Actively Recruiting

Qnasl Reviews: What are patients saying about Qnasl?

Patient Review

11/14/2018

Qnasl for Inflammation of the Nose due to an Allergy

Qnasl was much more effective than any other allergy medication I've tried, hands down. The price is pretty steep, but when my allergies are bad, it's worth every penny.

Patient Review

5/24/2020

Qnasl for Inflammation of the Nose due to an Allergy

Out of all the allergy medications I've tried, Qnasal is by far the most effective at relieving my severe congestion and sneezing.

Patient Review

2/6/2016

Qnasl for Inflammation of the Nose due to an Allergy

Qnasl was much more effective for me than Flonase, but it's also way more expensive.

Patient Review

5/24/2020

Qnasl for Inflammation of the Nose due to an Allergy

Qnasal was the only allergy medication I found that helped with my severe congestion and sneezing.

4.7

Patient Review

8/10/2015

Qnasl for Inflammation of the Nose due to an Allergy

Easy to use, but unfortunately I didn't really see any results. In fact, I think it made my condition worse. Switched back to flonase and saw a marked improvement.

4.7

Patient Review

1/3/2019

Qnasl for Inflammation of the Nose due to an Allergy

This medication has been great for me. I had really bad allergies that would have me sneezing 20 times in a row, but since starting this treatment, I've barely had any issues. I'm usually pretty good about taking it twice a day like recommended, but sometimes once a day is enough to keep my symptoms at bay.

Patient Review

8/23/2016

Qnasl for Presence of Polyps in the Nose

Though my sinus issues were not resolved, this medication did provide some temporary relief. However, after a few days of taking the prescribed dosage I started to experience other problems like nosebleeds, a sore throat, and eventually lost my voice entirely. When I notified my doctor of these adverse effects, he told me to stop taking the medication immediately.

Patient Review

5/2/2017

Qnasl for Presence of Polyps in the Nose

The drug was effective, but I stopped being able to use it effectively after only a year.

Patient Review

12/11/2017

Qnasl for Inflammation of the Nose due to an Allergy

The treatment worked well, but it caused some burning and bloody noses.

2.3

Patient Review

3/14/2016

Qnasl for Inflammation of the Nose

This treatment is really effective and quick-acting. I've tried so many other products that haven't worked as well as this one. Plus, it doesn't make me tired or my heart race. I love it!

2.3

Patient Review

4/23/2015

Qnasl for Inflammation of the Nose due to an Allergy

Patient Review

4/23/2016

Qnasl for Inflammation of the Nose

Flonase has been a great help for my seasonal allergies with no negative side effects that I've experienced. It's very affordable, and the delivery system is top-notch.

Patient Review

3/25/2017

Qnasl for Inflammation of the Nose due to an Allergy

I've been using this product for a few years and have found that, while it does help to treat my symptoms, the canister usually runs out of gas long before it should. I contacted the company about this issue and was told to keep the canister upright at all times; however, this has not solved the problem.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about qnasl

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is QNASL a steroid?

"A nasal spray containing the corticosteroid beclomethasone dipropionate, Qnasl is used to treat nasal symptoms caused by seasonal or perennial allergic rhinitis (hay fever) in patients aged 12 or older."

Answered by AI

What is QNASL used for?

"QNASL® (beclomethasone dipropionate) Nasal Aerosol is a prescription medication that is used to treat seasonal nasal and year-round nasal allergy symptoms in patients that are 4 years of age or older."

Answered by AI

Has QNASL been discontinued?

"There is not a generic version of Qnasl (beclomethasone) available in the United States as of now."

Answered by AI

Is QNASL the same as Flonase?

"Flonase is a good choice for treating allergies of the nose, but it can cause nosebleeds if used for a long time. Qnasl is a good choice for treating runny and stuffy nose due to allergies for children ages 4 or older."

Answered by AI