Ponstel

Pain, Mild pain, Primary Dysmenorrhoea + 1 more
Treatment
3 FDA approvals
1 Active Study for Ponstel

What is Ponstel

Mefenamic acidThe Generic name of this drug
Treatment SummaryIbuprofen is a pain reliever, anti-inflammatory, and fever reducer. It works by blocking the production of chemicals in the body that lead to inflammation and pain.
Ponstelis the brand name
image of different drug pills on a surface
Ponstel Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Ponstel
Mefenamic acid
1967
14

Approved as Treatment by the FDA

Mefenamic acid, also known as Ponstel, is approved by the FDA for 3 uses such as Pain and Mild pain .
Pain
Mild pain
Primary Dysmenorrhoea

Effectiveness

How Ponstel Affects PatientsMefenamic acid is a type of nonsteroidal anti-inflammatory drug (NSAID) used to reduce inflammation, provide pain relief, and reduce fever. It works by blocking the body's production of a certain type of hormone (prostaglandin) that contributes to inflammation.
How Ponstel works in the bodyMefenamic acid works by blocking two types of receptors in the body, COX-1 and COX-2. These receptors are responsible for inflammation and pain, so when Mefenamic acid blocks them, it helps reduce pain and inflammation.

When to interrupt dosage

The recommended dosage of Ponstel is contingent upon the diagnosed circumstance, such as Pain, Muscle Cramp and Primary Dysmenorrhoea. The amount of dosage relies upon the administration approach noted in the table below.
Condition
Dosage
Administration
Pain
, 250.0 mg
, Capsule, Capsule - Oral, Oral
Mild pain
, 250.0 mg
, Capsule, Capsule - Oral, Oral
Primary Dysmenorrhoea
, 250.0 mg
, Capsule, Capsule - Oral, Oral
Muscle Cramp
, 250.0 mg
, Capsule, Capsule - Oral, Oral

Warnings

Ponstel Contraindications
Condition
Risk Level
Notes
cardiac bypass surgery
Do Not Combine
Stomach Ulcer
Do Not Combine
preexisting renal disease
Do Not Combine
Inflammatory Bowel Diseases
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Mefenamic Acid may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Mefenamic Acid may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Mefenamic Acid may interact with Pulse Frequency
There are 20 known major drug interactions with Ponstel.
Common Ponstel Drug Interactions
Drug Name
Risk Level
Description
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Mefenamic acid.
Epirubicin
Major
The metabolism of Epirubicin can be decreased when combined with Mefenamic acid.
Macimorelin
Major
The therapeutic efficacy of Macimorelin can be decreased when used in combination with Mefenamic acid.
Methotrexate
Major
The serum concentration of Methotrexate can be increased when it is combined with Mefenamic acid.
Mifamurtide
Major
The therapeutic efficacy of Mifamurtide can be decreased when used in combination with Mefenamic acid.
Ponstel Toxicity & Overdose RiskThe lowest toxic dose of this drug in rats has been found to be 740mg/kg. Overdosing on this drug may cause severe abdominal pain, vomiting resembling coffee grounds, black stools, ringing in the ears, changes in urine output, abnormal heart rate, muscle weakness, slow or shallow breathing, confusion, severe headache, or loss of consciousness.
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Ponstel Novel Uses: Which Conditions Have a Clinical Trial Featuring Ponstel?

An ongoing investigation involving 4 trials is assessing the potential of Ponstel to ameliorate Mild pain, Primary Dysmenorrhoea and Muscle Cramps.
Condition
Clinical Trials
Trial Phases
Pain
0 Actively Recruiting
Primary Dysmenorrhoea
1 Actively Recruiting
Not Applicable
Muscle Cramp
0 Actively Recruiting
Mild pain
0 Actively Recruiting

Ponstel Reviews: What are patients saying about Ponstel?

5Patient Review
8/4/2010
Ponstel for Painful Periods
For years, I've suffered from debilitating cramps brought on by my period. Endometriosis made it hard to do anything when I had my period--I couldn't move, eat, or use the restroom without being in excruciating pain. Thankfully, my doctor put me on Ponstel and it has changed my life for the better. Now, I can actually enjoy my life during my menstrual cycle instead of counting down the days until it's over.
5Patient Review
12/12/2010
Ponstel for Painful Periods
This medication has been an absolute life-saver. I used to get so sick during my period that it would ruin my school performance and social life, but now I don't have to worry about that anymore. I highly recommend this to anyone who suffers from painful periods.
5Patient Review
3/16/2011
Ponstel for Painful Periods
Ponstel and Hydrocodone have been a godsend for my endometriosis-related cramps. I went from being in so much pain that it would wake me up at night to being able to sleep soundly through the night. Thank you, Dr. Henry!
5Patient Review
7/11/2014
Ponstel for Painful Periods
I've been taking this medication for 30 years now, and it's still the best one I've found for managing painful periods.
4.7Patient Review
5/6/2010
Ponstel for Painful Periods
I was a bit skeptical at first, but this product really does work! I had shorter, less painful periods after using it the second and third time. If it can completely reduce the pain, I may stop taking medication for my cramps altogether.
View All Reviews
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Patient Q&A Section about ponstel

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Ponstel used for?

"Mefenamic acid inhibits the inflammation process to reduce pain and swelling."

Answered by AI

Is Ponstel used for fever?

"rouj

Ponstan (mefenamic acid) can also be used to control fever. It is available in a suspension concentration of 50mg/5ml, and the recommended dose is 25mg/kg per day in divided doses. This means that an 8kg child should receive 5ml every 6 hours."

Answered by AI

Is mefenamic acid same as ibuprofen?

"It was found that mefenamic acid and ibuprofen had a similar effect in reducing pain and inflammation, and that there were few side effects apart from drowsiness in some cases."

Answered by AI

Is PONSTAN a good painkiller?

"Ponstan is a medication used to help with cramps during menstruation and to treat heavy periods. Additionally, it can be used to help with pain relief in injuries such as muscle sprains, strains, or tendonitis, as well as dental pain."

Answered by AI

Clinical Trials for Ponstel

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