Permethrin
Scabies, lice of the pubic area, Norwegian scabies + 1 more
Treatment
3 FDA approvals
2 Active Studies for Permethrin
Treatment for
Scabies
What is Permethrin
Permethrin
The Generic name of this drug
Treatment Summary
Permethrin is an insecticide used to treat lice and scabies. It is a yellow to light orange-brown colored liquid or solid material.
Elimite
is the brand name
Permethrin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Elimite
Permethrin
1989
61
Approved as Treatment by the FDA
Permethrin, otherwise called Elimite, is approved by the FDA for 3 uses like Scabies <infestation> and Scabies .
Scabies <infestation>
Scabies
Head
Effectiveness
How Permethrin Affects Patients
Permethrin is a type of insecticide that is effective against a wide range of bugs, such as lice, ticks, fleas, mites, and other tiny animals.
How Permethrin works in the body
Permethrin disturbs the nerve cells of pests, preventing them from functioning correctly. It interferes with the flow of sodium ions in the cells, leading to paralysis.
When to interrupt dosage
The proposed dosage of Permethrin is reliant upon the determined affliction, such as Scabies, Head and lice of the pubic area. The sum of dosage depends on the procedure of delivery (e.g. Lotion or Rinse - Topical) represented in the table below.
Condition
Dosage
Administration
Scabies
0.01 mg/mL, , 0.05 mg/mg, 56.0 mg/mL, 5.0 %, 1.0 %, 0.0005 mg/mg, 10.0 mg/mL, 27.8 mg/mL
, Lotion, Topical, Lotion - Topical, Cream, Shampoo - Topical, Shampoo, Kit, Liquid, Liquid - Topical, Cream - Topical, Cutaneous, Cream - Cutaneous, Rinse, Rinse - Topical, Kit - Topical
lice of the pubic area
0.01 mg/mL, , 0.05 mg/mg, 56.0 mg/mL, 5.0 %, 1.0 %, 0.0005 mg/mg, 10.0 mg/mL, 27.8 mg/mL
, Lotion, Topical, Lotion - Topical, Cream, Shampoo - Topical, Shampoo, Kit, Liquid, Liquid - Topical, Cream - Topical, Cutaneous, Cream - Cutaneous, Rinse, Rinse - Topical, Kit - Topical
Norwegian scabies
0.01 mg/mL, , 0.05 mg/mg, 56.0 mg/mL, 5.0 %, 1.0 %, 0.0005 mg/mg, 10.0 mg/mL, 27.8 mg/mL
, Lotion, Topical, Lotion - Topical, Cream, Shampoo - Topical, Shampoo, Kit, Liquid, Liquid - Topical, Cream - Topical, Cutaneous, Cream - Cutaneous, Rinse, Rinse - Topical, Kit - Topical
Head
0.01 mg/mL, , 0.05 mg/mg, 56.0 mg/mL, 5.0 %, 1.0 %, 0.0005 mg/mg, 10.0 mg/mL, 27.8 mg/mL
, Lotion, Topical, Lotion - Topical, Cream, Shampoo - Topical, Shampoo, Kit, Liquid, Liquid - Topical, Cream - Topical, Cutaneous, Cream - Cutaneous, Rinse, Rinse - Topical, Kit - Topical
Warnings
There are 20 known major drug interactions with Permethrin.
Common Permethrin Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Minor
Permethrin may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Permethrin may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Permethrin may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Almasilate
Minor
Permethrin may decrease the excretion rate of Almasilate which could result in a higher serum level.
Alogliptin
Minor
Permethrin may decrease the excretion rate of Alogliptin which could result in a higher serum level.
Permethrin Toxicity & Overdose Risk
The lowest toxic dose of the drug for rats orally is between 430-4000mg/kg, and 2000mg/kg for rabbits when applied to the skin.
Permethrin Novel Uses: Which Conditions Have a Clinical Trial Featuring Permethrin?
A single clinical trial is presently underway to ascertain the potency of Permethrin in providing relief from Pubic Lice, Scabies and Norwegian Scabies.
Condition
Clinical Trials
Trial Phases
Head
1 Actively Recruiting
Not Applicable
lice of the pubic area
0 Actively Recruiting
Norwegian scabies
0 Actively Recruiting
Scabies
1 Actively Recruiting
Phase 4
Patient Q&A Section about permethrin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Is permethrin harmful to humans?
"Long-term side effects are largely unknown.
Permethrin is a pyrethroid that can have harmful effects if inhaled, ingested, or absorbed through skin. Formulations of permethrin can be non-toxic to moderately toxic, and short-term side effects can include irritation of the eyes, skin, nose, and throat, as well as potentially difficulty breathing. The long-term effects of permethrin are largely unknown."
Answered by AI
What is permethrin used for?
"Permethrin 1% lotion is used to treat head lice infections. It destroys both the lice and their eggs. The 5% cream is used to treat scabies infections by destroying the mites which cause scabies."
Answered by AI
How much permethrin is toxic to humans?
"The available data on neuro toxicity indicates that exposure to permethrin at a level of 6.8 × 10 −5 mg/kg per day is approximately 3 million times safe for daily human exposure."
Answered by AI
Is permethrin cancerous?
"Additionally, the Agency has classified permethrin as a substance that is "likely to be carcinogenic to humans" if it is ingested orally."
Answered by AI