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What is Noctiva
DesmopressinThe Generic name of this drug
Treatment SummaryDesmopressin (dDAVP) is a medication used to treat conditions that cause an excessive amount of urine, such as nocturnal enuresis, nocturia, and diabetes insipidus. It is a synthetic form of a pituitary hormone that helps regulate the body’s water content. Desmopressin is more effective and has fewer side effects than the natural hormone and is available in various forms such as nasal spray, intravenous solution, tablets, and lyophilized oral tablets. It was approved by the FDA in 2018 for the treatment of nocturia in adults. The active ingredient
Ddavpis the brand name
Noctiva Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Ddavp
Desmopressin
1978
101
Effectiveness
How Noctiva Affects PatientsDesmopressin is a drug that acts similarly to a natural hormone in the body (antidiuretic hormone or ADH) to reduce the amount of urine produced. It also increases the amount of factor VIII activity in patients with hemophilia and von Willebrand's disease type I. Desmopressin is less likely to cause an increase in blood pressure when compared to ADH, and intranasal administration of desmopressin produces effects that are about one-tenth as powerful as those from an equivalent dose administered by injection.
How Noctiva works in the bodyDesmopressin binds to special receptors in the cells that line the kidneys' tubes. This triggers a chain reaction inside the cells, which causes more water channels to be opened in the cell membrane. This makes it easier for water to move in and out of the cell.
When to interrupt dosage
The suggested dose of Noctiva depends on the detected condition, such as Minor Surgical Procedures, Pituitary Gland and Surgery, Hemophilia A. The dosage depends on the technique of delivery featured in the table below.Condition
Dosage
Administration
Hemophilia As
0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation
, Oral, Tablet, Tablet - Oral, Nasal, Solution, Solution - Nasal, Intravenous, Solution - Intravenous, Intravenous; Subcutaneous, Injection, solution, Injection, solution - Intravenous; Subcutaneous, Injection, Injection - Intravenous, Spray, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Spray, metered, Spray, metered - Nasal, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered, Aerosol, metered - Nasal, Tablet - Sublingual, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous
Hemophilia
0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation
, Oral, Tablet, Tablet - Oral, Nasal, Solution, Solution - Nasal, Intravenous, Solution - Intravenous, Intravenous; Subcutaneous, Injection, solution, Injection, solution - Intravenous; Subcutaneous, Injection, Injection - Intravenous, Spray, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Spray, metered, Spray, metered - Nasal, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered, Aerosol, metered - Nasal, Tablet - Sublingual, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous
Hemorrhage
0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation
, Oral, Tablet, Tablet - Oral, Nasal, Solution, Solution - Nasal, Intravenous, Solution - Intravenous, Intravenous; Subcutaneous, Injection, solution, Injection, solution - Intravenous; Subcutaneous, Injection, Injection - Intravenous, Spray, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Spray, metered, Spray, metered - Nasal, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered, Aerosol, metered - Nasal, Tablet - Sublingual, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous
von Willebrand Disease
0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation
, Oral, Tablet, Tablet - Oral, Nasal, Solution, Solution - Nasal, Intravenous, Solution - Intravenous, Intravenous; Subcutaneous, Injection, solution, Injection, solution - Intravenous; Subcutaneous, Injection, Injection - Intravenous, Spray, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Spray, metered, Spray, metered - Nasal, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered, Aerosol, metered - Nasal, Tablet - Sublingual, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous
Primary Nocturnal Enuresis
0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation
, Oral, Tablet, Tablet - Oral, Nasal, Solution, Solution - Nasal, Intravenous, Solution - Intravenous, Intravenous; Subcutaneous, Injection, solution, Injection, solution - Intravenous; Subcutaneous, Injection, Injection - Intravenous, Spray, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Spray, metered, Spray, metered - Nasal, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered, Aerosol, metered - Nasal, Tablet - Sublingual, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous
Uremia
0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation
, Oral, Tablet, Tablet - Oral, Nasal, Solution, Solution - Nasal, Intravenous, Solution - Intravenous, Intravenous; Subcutaneous, Injection, solution, Injection, solution - Intravenous; Subcutaneous, Injection, Injection - Intravenous, Spray, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Spray, metered, Spray, metered - Nasal, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered, Aerosol, metered - Nasal, Tablet - Sublingual, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous
Pituitary Surgery
0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation
, Oral, Tablet, Tablet - Oral, Nasal, Solution, Solution - Nasal, Intravenous, Solution - Intravenous, Intravenous; Subcutaneous, Injection, solution, Injection, solution - Intravenous; Subcutaneous, Injection, Injection - Intravenous, Spray, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Spray, metered, Spray, metered - Nasal, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered, Aerosol, metered - Nasal, Tablet - Sublingual, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous
Polyuria
0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation
, Oral, Tablet, Tablet - Oral, Nasal, Solution, Solution - Nasal, Intravenous, Solution - Intravenous, Intravenous; Subcutaneous, Injection, solution, Injection, solution - Intravenous; Subcutaneous, Injection, Injection - Intravenous, Spray, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Spray, metered, Spray, metered - Nasal, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered, Aerosol, metered - Nasal, Tablet - Sublingual, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous
Nocturia
0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation
, Oral, Tablet, Tablet - Oral, Nasal, Solution, Solution - Nasal, Intravenous, Solution - Intravenous, Intravenous; Subcutaneous, Injection, solution, Injection, solution - Intravenous; Subcutaneous, Injection, Injection - Intravenous, Spray, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Spray, metered, Spray, metered - Nasal, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered, Aerosol, metered - Nasal, Tablet - Sublingual, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous
Polyuria
0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation
, Oral, Tablet, Tablet - Oral, Nasal, Solution, Solution - Nasal, Intravenous, Solution - Intravenous, Intravenous; Subcutaneous, Injection, solution, Injection, solution - Intravenous; Subcutaneous, Injection, Injection - Intravenous, Spray, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Spray, metered, Spray, metered - Nasal, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered, Aerosol, metered - Nasal, Tablet - Sublingual, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous
Polydipsia
0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation
, Oral, Tablet, Tablet - Oral, Nasal, Solution, Solution - Nasal, Intravenous, Solution - Intravenous, Intravenous; Subcutaneous, Injection, solution, Injection, solution - Intravenous; Subcutaneous, Injection, Injection - Intravenous, Spray, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Spray, metered, Spray, metered - Nasal, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered, Aerosol, metered - Nasal, Tablet - Sublingual, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous
von Willebrand Disease
0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation
, Oral, Tablet, Tablet - Oral, Nasal, Solution, Solution - Nasal, Intravenous, Solution - Intravenous, Intravenous; Subcutaneous, Injection, solution, Injection, solution - Intravenous; Subcutaneous, Injection, Injection - Intravenous, Spray, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Spray, metered, Spray, metered - Nasal, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered, Aerosol, metered - Nasal, Tablet - Sublingual, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous
Surgery, Hemophilia A
0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation
, Oral, Tablet, Tablet - Oral, Nasal, Solution, Solution - Nasal, Intravenous, Solution - Intravenous, Intravenous; Subcutaneous, Injection, solution, Injection, solution - Intravenous; Subcutaneous, Injection, Injection - Intravenous, Spray, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Spray, metered, Spray, metered - Nasal, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered, Aerosol, metered - Nasal, Tablet - Sublingual, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous
pituitary trauma
0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation
, Oral, Tablet, Tablet - Oral, Nasal, Solution, Solution - Nasal, Intravenous, Solution - Intravenous, Intravenous; Subcutaneous, Injection, solution, Injection, solution - Intravenous; Subcutaneous, Injection, Injection - Intravenous, Spray, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Spray, metered, Spray, metered - Nasal, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered, Aerosol, metered - Nasal, Tablet - Sublingual, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous
Hemorrhage
0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation
, Oral, Tablet, Tablet - Oral, Nasal, Solution, Solution - Nasal, Intravenous, Solution - Intravenous, Intravenous; Subcutaneous, Injection, solution, Injection, solution - Intravenous; Subcutaneous, Injection, Injection - Intravenous, Spray, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Spray, metered, Spray, metered - Nasal, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered, Aerosol, metered - Nasal, Tablet - Sublingual, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous
Central Diabetes Insipidus
0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation
, Oral, Tablet, Tablet - Oral, Nasal, Solution, Solution - Nasal, Intravenous, Solution - Intravenous, Intravenous; Subcutaneous, Injection, solution, Injection, solution - Intravenous; Subcutaneous, Injection, Injection - Intravenous, Spray, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Spray, metered, Spray, metered - Nasal, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered, Aerosol, metered - Nasal, Tablet - Sublingual, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous
Minor Surgical Procedures
0.1 mg, 0.2 mg, , 0.1 mg/mL, 0.004 mg/mL, 0.0001 mg/mL, 0.01 mg, 0.06 mg, 0.12 mg, 0.24 mg, 0.025 mg, 0.05 mg, 1.5 mg/mL, 0.00083 mg, 0.00166 mg, 0.0277 mg, 0.0553 mg, 0.015 mg/mL, 0.01 mg/pump actuation, 0.15 mg/pump actuation
, Oral, Tablet, Tablet - Oral, Nasal, Solution, Solution - Nasal, Intravenous, Solution - Intravenous, Intravenous; Subcutaneous, Injection, solution, Injection, solution - Intravenous; Subcutaneous, Injection, Injection - Intravenous, Spray, Spray - Nasal, Intramuscular; Intravenous; Subcutaneous, Liquid, Liquid - Intramuscular; Intravenous; Subcutaneous, Spray, metered, Spray, metered - Nasal, Sublingual, Tablet, orally disintegrating - Sublingual, Tablet, orally disintegrating, Aerosol, metered, Aerosol, metered - Nasal, Tablet - Sublingual, Injection - Intravenous; Subcutaneous, Solution - Intramuscular; Intravenous; Subcutaneous, Solution - Intravenous; Subcutaneous
Warnings
Noctiva has three contraindications and should not be utilized if you experience any of the conditions given in the table below.Noctiva ContraindicationsCondition
Risk Level
Notes
history of hyponatremia
Do Not Combine
Renal Insufficiency
Do Not Combine
Hyponatremia
Do Not Combine
Common Noctiva Drug Interactions
Drug Name
Risk Level
Description
1-benzylimidazole
Minor
The risk or severity of hypertension can be increased when Desmopressin is combined with 1-benzylimidazole.
2,5-Dimethoxy-4-ethylamphetamine
Minor
The risk or severity of hypertension can be increased when Desmopressin is combined with 2,5-Dimethoxy-4-ethylamphetamine.
2,5-Dimethoxy-4-ethylthioamphetamine
Minor
The risk or severity of hypertension can be increased when Desmopressin is combined with 2,5-Dimethoxy-4-ethylthioamphetamine.
4-Bromo-2,5-dimethoxyamphetamine
Minor
The risk or severity of hypertension can be increased when Desmopressin is combined with 4-Bromo-2,5-dimethoxyamphetamine.
4-Methoxyamphetamine
Minor
The risk or severity of hypertension can be increased when Desmopressin is combined with 4-Methoxyamphetamine.
Noctiva Toxicity & Overdose RiskThe lowest toxic amount of desmopressin for humans is 0.3 µg/kg/10M. Overdosing on this drug can lead to low sodium levels in the body, which can cause seizures, confusion, drowsiness, irregular heartbeat, and swelling. If an overdose is suspected, reduce the dose or frequency of administration, or stop use if necessary. Additionally, it is recommended to check sodium levels in the blood and start medical treatment if needed.
Noctiva Novel Uses: Which Conditions Have a Clinical Trial Featuring Noctiva?
30 active trials are currently investigating the potential of Noctiva to alleviate Polyuria, Hemophilia A and Hemophilia B.Condition
Clinical Trials
Trial Phases
Surgery, Hemophilia A
0 Actively Recruiting
Polyuria
0 Actively Recruiting
Polydipsia
0 Actively Recruiting
Uremia
0 Actively Recruiting
pituitary trauma
0 Actively Recruiting
Polyuria
0 Actively Recruiting
Nocturia
6 Actively Recruiting
Phase 4, Not Applicable
Hemorrhage
13 Actively Recruiting
Phase 4, Phase 3, Not Applicable, Phase 1, Phase 2
Hemophilia
4 Actively Recruiting
Phase 3
von Willebrand Disease
2 Actively Recruiting
Phase 3
von Willebrand Disease
0 Actively Recruiting
Primary Nocturnal Enuresis
0 Actively Recruiting
Hemorrhage
0 Actively Recruiting
Minor Surgical Procedures
0 Actively Recruiting
Central Diabetes Insipidus
1 Actively Recruiting
Phase 1
Pituitary Surgery
0 Actively Recruiting
Hemophilia As
3 Actively Recruiting
Phase 3
Noctiva Reviews: What are patients saying about Noctiva?
3.7Patient Review
9/20/2018 Noctiva does work, however the cure is worse than the ailment. The drainage from this medicine is incredibly painful and unpleasant tasting. I thought it might get easier to use after time, but I finally gave up. It's like spraying liquid cayenne pepper up your nose. I would rather get up to pee a half dozen times than go through that pain again."
2.3Patient Review
9/22/2018 I recently started using this nasal spray, and was very disappointed. It burns terribly and causes my nose to run incessantly. My eyes water nonstop for about twenty minutes after using it. I don't think I'll be continuing to use this product.
2Patient Review
1/31/2019 The application of this treatment is unfortunately quite painful, making it suboptimal to use right before bed. That said, the treatment itself is effective.
Patient Q&A Section about noctiva
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Noctiva discontinued?
"Avadel will no longer be marketing Noctiva as of February 7th, 2019. This is due to the product's links to Nocturnal Polyuria (a condition involving overproduction of urine at night) in adults. There is also a risk of hyponatremia."
Answered by AI
Is Noctiva a prescription drug?
"Noctiva is a prescription medication used in adults who wake up 2 or more times during the night to urinate due to nocturnal polyuria, a condition where your body makes too much urine at night. Noctiva was not studied in patients younger than 50 years of age."
Answered by AI
What is Noctiva used for?
"Noctiva is a medication meant to treat nocturia, or having to wake up at night to urinate, in adults who have to do so at least twice a night. This is caused by nocturnal polyuria, which is defined as producing urine at night that makes up more than a third of your daily urine production."
Answered by AI
How much does Noctiva cost?
"Noctiva nasal spray is around $453 for a supply of 3.8 grams."
Answered by AI