Niravam

Panic Disorder, Generalized Anxiety Disorder

Treatment

10 Active Studies for Niravam

Treatment for

Panic Disorder

What is Niravam

AlprazolamThe Generic name of this drug

Treatment SummaryAlprazolam is a medication used to treat anxiety and panic disorders. It should not be taken with medications that contain CYP3A inhibitors. When stopping alprazolam, it is important to do so gradually to avoid withdrawal symptoms. Common side effects of the drug include drowsiness and sedation. Alprazolam has been known to be abused in combination with alcohol, which can lead to coma or death. It was approved by the FDA in 1981.

Alprazolamis the brand name

image of different drug pills on a surface

Niravam Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Alprazolam

1981

518

Effectiveness

How Niravam Affects PatientsAlprazolam is a type of medication that works by calming the brain and reducing nerve activity. It must be used carefully because taking it with opioids, such as painkillers, can cause serious side effects and even death. People with breathing problems are especially at risk of these effects. Alprazolam can also be habit-forming, so it needs to be taken as prescribed by a doctor and monitored carefully. Stopping the medication should be done gradually to avoid withdrawal symptoms, which can be severe. Mothers who take alprazolam late in pregnancy may give birth to babies with sedation and withdrawal issues. Alp

How Niravam works in the bodyGABA type-A (GABA<sub>A</sub>) receptors help regulate neurotransmission by allowing chloride ions to flow in and out of cells. These receptors are made up of several different subunits, and each has a special binding site for a benzodiazepine drug. When the drug binds to the receptor, it helps open the pore, allowing the chloride ions to flow and produce an inhibitory signal. Different combinations of subunits have slightly different benzodiazepine binding sites that can create different effects. Scientists are still trying to understand how these different sites affect the action of benzodiazepines.

When to interrupt dosage

The proposed quantity of Niravam is subject to the diagnosed condition. The amount of dosage is contingent upon the approach of delivery as outlined in the table below.

Condition

Dosage

Administration

Generalized Anxiety Disorder

, 1.0 mg, 2.0 mg, 3.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL

Oral, , Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Kit, Solution, concentrate, Solution, concentrate - Oral

Panic Disorder

, 1.0 mg, 2.0 mg, 3.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL

Warnings

Niravam Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Alprazolam may interact with Pulse Frequency

There are 20 known major drug interactions with Niravam.

Common Niravam Drug Interactions

Drug Name

Risk Level

Description

Axitinib

Major

The metabolism of Axitinib can be decreased when combined with Alprazolam.

Azelastine

Major

Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Azelastine.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Alprazolam.

Carbamazepine

Major

The metabolism of Carbamazepine can be decreased when combined with Alprazolam.

Copanlisib

Major

The metabolism of Copanlisib can be decreased when combined with Alprazolam.

Niravam Toxicity & Overdose RiskTaking too much Alprazolam can cause drowsiness, confusion, clumsiness, unconsciousness, and death. Mixing it with alcohol increases the risk of overdose. If an overdose is suspected, medical professionals should monitor the patient's respiration, pulse, and blood pressure. Treatment may include stomach pumping and intravenous fluids. If the patient's blood pressure is low, they may be given medication to raise it. In some cases, a benzodiazepine receptor antagonist can be used alongside other treatments. The toxic dose of Alprazolam in rats is between 331-2171mg/kg.

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Niravam Novel Uses: Which Conditions Have a Clinical Trial Featuring Niravam?

A total of 47 active clinical trials are examining the potential of Niravam to manage Generalized Anxiety Disorder.

Condition

Clinical Trials

Trial Phases

Generalized Anxiety Disorder

3 Actively Recruiting

Not Applicable, Phase 2

Panic Disorder

9 Actively Recruiting

Not Applicable

Niravam Reviews: What are patients saying about Niravam?

5Patient Review

1/8/2008

Niravam for Panic Disorder

This medicine quickly stopped my panic attack, though I did feel a bit out of it for the rest of the day. A tiny dose (0.25mg) worked within five minutes or so. I only need to use this four to five times per year, which is great.

5Patient Review

4/25/2011

Niravam for Panic Disorder

I've had generally positive experiences taking this medication. I don't take it on a regular basis, but rather as needed. This has helped me feel better without needing to be constantly reliant on the medication.

5Patient Review

5/11/2010

Niravam for Anxious

If you suffer from PTSD or anxiety, I cannot recommend this medication enough. It has completely changed my quality of life for the better.

5Patient Review

9/8/2013

Niravam for Repeated Episodes of Anxiety

I've been taking this for over two decades and it's always helped me when I need it. Though, I have had seizures before when going off of the medication. It's great for my panic attacks and stomach problems.

5Patient Review

3/19/2008

Niravam for Panic Disorder

Worked very quickly, which was great for me given how high-stress my job is.

View All Reviews

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Patient Q&A Section about niravam

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Niravam discontinued?

"The Niravam brand name has been discontinued as of February 21, 2022. If generic versions of this product have been approved by the FDA, there may be generic equivalents available."

Answered by AI

Is Niravam the same as Xanax?

"Alprazolam is a prescription drug that is available in generic form. The brand names for alprazolam are Xanax, Xanax XR, and Niravam. You need a prescription from your doctor or other health-care professional to obtain this drug."

Answered by AI

Is alprazolam the same as Xanax?

"Medications like Xanax help to control the levels of these chemicals )

The active ingredient in Xanax is called alprazolam. It works by helping to regulate the levels of chemicals in the brain that are responsible for causing anxiety symptoms."

Answered by AI

Is Niravam a controlled substance?

"NIRAVAM belongs to a class of drugs known as benzodiazepines, which have the potential to be addictive and lead to physical and psychological dependence."

Answered by AI