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What is Niravam
AlprazolamThe Generic name of this drug
Treatment SummaryAlprazolam is a medication used to treat anxiety and panic disorders. It should not be taken with medications that contain CYP3A inhibitors. When stopping alprazolam, it is important to do so gradually to avoid withdrawal symptoms. Common side effects of the drug include drowsiness and sedation. Alprazolam has been known to be abused in combination with alcohol, which can lead to coma or death. It was approved by the FDA in 1981.
Alprazolamis the brand name
Niravam Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Alprazolam
Alprazolam
1981
518
Effectiveness
How Niravam Affects PatientsAlprazolam is a type of medication that works by calming the brain and reducing nerve activity. It must be used carefully because taking it with opioids, such as painkillers, can cause serious side effects and even death. People with breathing problems are especially at risk of these effects. Alprazolam can also be habit-forming, so it needs to be taken as prescribed by a doctor and monitored carefully. Stopping the medication should be done gradually to avoid withdrawal symptoms, which can be severe. Mothers who take alprazolam late in pregnancy may give birth to babies with sedation and withdrawal issues. Alp
How Niravam works in the bodyGABA type-A (GABA<sub>A</sub>) receptors help regulate neurotransmission by allowing chloride ions to flow in and out of cells. These receptors are made up of several different subunits, and each has a special binding site for a benzodiazepine drug. When the drug binds to the receptor, it helps open the pore, allowing the chloride ions to flow and produce an inhibitory signal. Different combinations of subunits have slightly different benzodiazepine binding sites that can create different effects. Scientists are still trying to understand how these different sites affect the action of benzodiazepines.
When to interrupt dosage
The proposed quantity of Niravam is subject to the diagnosed condition. The amount of dosage is contingent upon the approach of delivery as outlined in the table below.Condition
Dosage
Administration
Generalized Anxiety Disorder
, 1.0 mg, 2.0 mg, 3.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL
Oral, , Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Kit, Solution, concentrate, Solution, concentrate - Oral
Panic Disorder
, 1.0 mg, 2.0 mg, 3.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL
Oral, , Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Kit, Solution, concentrate, Solution, concentrate - Oral
Warnings
Niravam ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Alprazolam may interact with Pulse Frequency
Common Niravam Drug Interactions
Drug Name
Risk Level
Description
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Alprazolam.
Azelastine
Major
Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Alprazolam.
Carbamazepine
Major
The metabolism of Carbamazepine can be decreased when combined with Alprazolam.
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Alprazolam.
Niravam Toxicity & Overdose RiskTaking too much Alprazolam can cause drowsiness, confusion, clumsiness, unconsciousness, and death. Mixing it with alcohol increases the risk of overdose. If an overdose is suspected, medical professionals should monitor the patient's respiration, pulse, and blood pressure. Treatment may include stomach pumping and intravenous fluids. If the patient's blood pressure is low, they may be given medication to raise it. In some cases, a benzodiazepine receptor antagonist can be used alongside other treatments. The toxic dose of Alprazolam in rats is between 331-2171mg/kg.
Niravam Novel Uses: Which Conditions Have a Clinical Trial Featuring Niravam?
A total of 47 active clinical trials are examining the potential of Niravam to manage Generalized Anxiety Disorder.Condition
Clinical Trials
Trial Phases
Generalized Anxiety Disorder
32 Actively Recruiting
Not Applicable, Phase 2, Phase 3, Phase 1, Phase 4
Panic Disorder
17 Actively Recruiting
Not Applicable, Phase 2
Niravam Reviews: What are patients saying about Niravam?
5Patient Review
1/8/2008 This medicine quickly stopped my panic attack, though I did feel a bit out of it for the rest of the day. A tiny dose (0.25mg) worked within five minutes or so. I only need to use this four to five times per year, which is great.
5Patient Review
4/25/2011 I've had generally positive experiences taking this medication. I don't take it on a regular basis, but rather as needed. This has helped me feel better without needing to be constantly reliant on the medication.
5Patient Review
5/11/2010 If you suffer from PTSD or anxiety, I cannot recommend this medication enough. It has completely changed my quality of life for the better.
5Patient Review
9/8/2013 I've been taking this for over two decades and it's always helped me when I need it. Though, I have had seizures before when going off of the medication. It's great for my panic attacks and stomach problems.
5Patient Review
3/19/2008 Worked very quickly, which was great for me given how high-stress my job is.
5Patient Review
8/1/2008 After being let go from my job unexpectedly, I was left unable to sleep due to anxiety and racing thoughts. My psychiatrist prescribed Niravam and I found that it worked almost instantly to help me fall asleep at night. During the week I take 1/2 a pill, and on weekends I take a whole pill. I haven't yet taken Niravam during the day, but may soon try it as my current job is very stressful.
5Patient Review
1/12/2009 I had a really great night's sleep after using this treatment.
5Patient Review
12/28/2009 This medication is effective in quickly relieving symptoms, but it can be addictive.
5Patient Review
3/21/2008 This medication typically prevents panic attacks for me that are brought about by TSS or anxiety.
5Patient Review
4/13/2009 This treatment helps me to feel more calm and relaxed very quickly.
4.7Patient Review
12/8/2008 I've tried a lot of sleeping aids, and this one is by far the best. It's hard to get from doctors, but it's worth it.
4.7Patient Review
6/17/2009 My neurologist prescribed this medication, and it's done wonders for my sleep and panic disorder. I used to only take 2mg, but now 6mg isn't working as well. I want to find a stronger medicine so that eventually I can taper off. It's frustrating when the medicine stops being effective. I've wondered if my pharmacy is selling me expired medications. What should I do?
4.3Patient Review
7/27/2009 I've used this medication in the past for panic attacks and it's been really effective. I haven't needed it in a couple years, but I'm currently going through some tough times and feeling like I might need to take it again. I'm breastfeeding, though, so I'm worried about interactions while nursing. Does anyone have any thoughts on this? I just want to be "OK" again without causing any problems with my 5-month-old.
4.3Patient Review
1/21/2011 I've just started this treatment, and I have to say that it's been working really well for me. I take it at work, and I definitely feel a lot better now.
4Patient Review
1/7/20082.3Patient Review
1/15/2009 This was the only anxiety medication that worked quickly and efficiently for me.
Patient Q&A Section about niravam
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Niravam discontinued?
"The Niravam brand name has been discontinued as of February 21, 2022. If generic versions of this product have been approved by the FDA, there may be generic equivalents available."
Answered by AI
Is Niravam the same as Xanax?
"Alprazolam is a prescription drug that is available in generic form. The brand names for alprazolam are Xanax, Xanax XR, and Niravam. You need a prescription from your doctor or other health-care professional to obtain this drug."
Answered by AI
Is Niravam a controlled substance?
"NIRAVAM belongs to a class of drugs known as benzodiazepines, which have the potential to be addictive and lead to physical and psychological dependence."
Answered by AI