What is Naprosyn
NaproxenThe Generic name of this drug
Treatment SummaryNaproxen is an over-the-counter pain reliever used to treat various types of pain, such as acute pain and pain related to rheumatic diseases. It is generally well tolerated and effective, making it a common first choice for treating pain. Naproxen comes in immediate release and delayed release forms, and is also available in combination with other medications to treat migraines or reduce the risk of gastric ulcers.
Naprosynis the brand name
Naprosyn Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Naprosyn
Naproxen
1976
1251
Approved as Treatment by the FDA
Naproxen, otherwise known as Naprosyn, is approved by the FDA for 11 uses including Osteoarthritis (OA) and Back .Osteoarthritis (OA)
Used to treat Osteoarthritis (OA) in combination with Esomeprazole
Back
Menstrual Distress (Dysmenorrhea)
Toothache
Fever
Acute Coryza
Used to treat Acute Migraine in combination with Sumatriptan
Juvenile arthritis
Used to treat Juvenile Idiopathic Arthritis (JIA) in combination with Esomeprazole
Rheumatoid Arthritis
Used to treat Rheumatoid Arthritis in combination with Esomeprazole
Ankylosing Spondylitis
Used to treat Ankylosing Spondylitis (AS) in combination with Esomeprazole
Inflammation
Used to treat articular inflammation in combination with Esomeprazole
Migraine
Effectiveness
How Naprosyn Affects PatientsNaproxen is a non-selective NSAID used to relieve pain, reduce inflammation and lower fever. It works by blocking a certain enzyme, which reduces the amount of prostaglandins in the body. However, naproxen can have negative effects, such as raising blood pressure and increasing the risk of upper gastrointestinal bleeding. People taking corticosteroids or anticoagulants, or who have a history of stomach ulcers, are more likely to experience these side effects.
How Naprosyn works in the bodyNaproxen works to reduce pain, fever and inflammation by blocking two enzymes in the body: COX-1 and COX-2. COX-1 is usually found in normal tissues like the stomach lining and is always active, while COX-2 produces prostaglandins that are responsible for pain, fever, and inflammation. By blocking these two enzymes, naproxen can provide relief from pain, fever, and inflammation without causing many of the unwanted side effects like gastrointestinal upset and renal toxicities.
When to interrupt dosage
The proposed dosage of Naprosyn is contingent upon the established condition, such as Menstrual Distress (Dysmenorrhea), Migraine and Toothache. The amount of dosage fluctuates as per the technique of delivery (e.g. Tablet, extended release or Tablet, delayed release) specified in the following table.Condition
Dosage
Administration
Migraine
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Arthritis, Gouty
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Osteoarthritis
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Toothache
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Primary Dysmenorrhoea
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Sinusitis
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Menstrual Distress (Dysmenorrhea)
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Tendinitis
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Fever
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
prophylaxis of migraine headaches
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Influenza
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Migraine
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Back
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Bursitis
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Ankylosing Spondylitis
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Acute Coryza
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Collagen Diseases
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Osteoarthritis (OA)
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Nasal Congestion
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Muscle Spasms
, 220.0 mg, 375.0 mg, 500.0 mg, 125.0 mg, 750.0 mg, 60.0 mg, 200.0 mg, 550.0 mg, 50.0 mg/mL, 25.0 mg/mL, 125.0 mg/mL, 275.0 mg, 250.0 mg, 5.0 mg/mg, 1.0 mg/mg, 1000.0 mg, 2.2 mg/mg, 105.0 mg, 210.0 mg
Tablet, extended release, Tablet, delayed release, Oral, Tablet - Oral, Tablet, film coated, Capsule, liquid filled - Oral, Tablet, coated - Oral, Capsule - Oral, Kit, , Tablet, for suspension, Kit - Oral, Tablet, delayed release - Oral, Cream - Topical, Tablet, extended release - Oral, Oral; Topical, Capsule, liquid filled, Tablet, Tablet, multilayer, extended release - Oral, Suspension - Oral, Suppository - Rectal, Tablet, film coated - Oral, Tablet, film coated, extended release, Kit; Tablet - Oral, Suspension, Cream; Kit; Tablet, Rectal, Kit - Oral; Topical, Cream; Kit; Tablet - Oral; Topical, Tablet, film coated, extended release - Oral, Kit; Tablet, Capsule, Tablet, multilayer, extended release, Tablet, coated, Topical, Suppository, Kit - Topical, Tablet, for suspension - Oral
Warnings
Naprosyn ContraindicationsCondition
Risk Level
Notes
Coronary Artery Bypass Grafting
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Naproxen may interact with Toxoplasma Infections
Severe Hypersensitivity Reactions
Do Not Combine
Naproxen may interact with Toxoplasma Infections
Severe Hypersensitivity Reactions
Do Not Combine
Naproxen may interact with Toxoplasma Infections
Common Naprosyn Drug Interactions
Drug Name
Risk Level
Description
Amiodarone
Major
The metabolism of Amiodarone can be decreased when combined with Naproxen.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Naproxen.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Naproxen.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Naproxen.
Erlotinib
Major
The metabolism of Erlotinib can be decreased when combined with Naproxen.
Naprosyn Toxicity & Overdose RiskNaproxen is available without a prescription, but this raises the risk of an overdose. Mild symptoms of an overdose include drowsiness, fatigue, stomach pain, nausea, and vomiting. There is no cure for an overdose but symptoms usually go away with supportive care. Naproxen is not recommended for pregnant women in the third trimester because it can cause a premature closure of the fetal ductus arteriosus.
Naprosyn Novel Uses: Which Conditions Have a Clinical Trial Featuring Naprosyn?
635 active clinical trials are currently investigating the potential of Naprosyn to provide relief from Chronic Pain, Migraine and Juvenile Rheumatoid Arthritis.Condition
Clinical Trials
Trial Phases
Migraine
72 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Phase 3
Chronic Pain
186 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Phase 4, Early Phase 1
Bursitis
9 Actively Recruiting
Phase 4, Not Applicable, Phase 1
Rheumatoid Arthritis
73 Actively Recruiting
Not Applicable, Phase 1, Phase 4, Phase 3, Phase 2
Juvenile arthritis
15 Actively Recruiting
Phase 3, Phase 2, Not Applicable, Phase 1
Osteoarthritis
163 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Phase 1, Phase 2, Early Phase 1
Migraine
61 Actively Recruiting
Not Applicable, Phase 1, Phase 4, Phase 2, Phase 3
Primary Dysmenorrhoea
4 Actively Recruiting
Phase 4, Not Applicable
Post Traumatic Pain
0 Actively Recruiting
Toothache
4 Actively Recruiting
Phase 1, Phase 2, Phase 3, Phase 4
Postoperative Pain
15 Actively Recruiting
Phase 4, Phase 3, Not Applicable, Early Phase 1
Osteoarthritis (OA)
0 Actively Recruiting
Muscle Spasms
0 Actively Recruiting
prophylaxis of migraine headaches
0 Actively Recruiting
Rheumatoid Arthritis, Juvenile
3 Actively Recruiting
Not Applicable, Phase 3
Sinusitis
19 Actively Recruiting
Not Applicable, Phase 3, Early Phase 1, Phase 1, Phase 2, Phase 4
Arthritis, Gouty
0 Actively Recruiting
Tendinitis
1 Actively Recruiting
Not Applicable
Fever
27 Actively Recruiting
Phase 2, Phase 1, Phase 3, Phase 4, Not Applicable, Early Phase 1
Hay Fever
1 Actively Recruiting
Phase 3
Naprosyn Reviews: What are patients saying about Naprosyn?
5Patient Review
2/21/2012 I'm a bit worried about taking this drug because I'm only 13. The pain is really unbearable, though. Is it addictive? Can someone let me know if it's worth trying?
5Patient Review
1/25/2018 I was given this medication for the chronic pain that comes with fatigue syndrome. Within hours of taking the first pill, I went numb on one side of my body and felt very weak and dizzy. I stopped taking them after that because the headaches were awful and lasted for months. Even now, years later, I still get strange stars in front of my eyes sometimes.
5Patient Review
1/20/2022 These meds are great for heel spurs. I’m on my feet 12 hours a day for 4 days, and I was able to make it all four days without pain. Very happy.
5Patient Review
11/26/2013 After taking this medication for a couple of months, I developed an "itchy" throat with a very dry cough. After stopping it for 2 days the itchiness has gone away and so has the cough.
5Patient Review
3/29/2012 This medication did not relieve any of my finger joint pain. In fact, after using it for two months daily, I developed a severe rash that itched incessantly.
5Patient Review
11/15/20114Patient Review
4/19/2012 I was prescribed this medication by my doctor to treat neck pain. I took the 500 mg dosage twice a day, as directed. However, after only two weeks on the medication, I began having black stool—a sign of bleeding in the stomach. Immediately upon discovering this side effect, I ceased taking all medications and wonder if I need to tell my doctor right away.
4Patient Review
11/5/2012 I was in a lot of pain before taking this medication, to the point where I needed a cane. But after just two days, I'm feeling great!
4Patient Review
7/31/2013 my boyfriend has had some serious side effects from this medication. He's been fainting, nauseous, and experiencing more chest pain, excessive sweating, and other issues. This just isn't a good drug. How long does it take for the medicine to leave his system?
4Patient Review
7/11/20113.3Patient Review
8/5/2013 Day 3 after stopping the medication and I'm still in a lot of pain. This drug is terrible and should be banned.
3Patient Review
8/27/20111.7Patient Review
5/22/20111Patient Review
4/8/2011Patient Q&A Section about naprosyn
What are the side effects of taking Naprosyn?
"The following side effects may occur: an upset stomach, nausea, heartburn, headache, drowsiness, dizziness. If any of these effects continue or worsen, notify your doctor or pharmacist immediately." - Anonymous Online Contributor
Unverified Answer
What are Naprosyn used for?
"Naproxen can be used to relieve pain from conditions such as headaches, muscle aches, tendonitis, dental pain, and menstrual cramps. It can also reduce pain, swelling, and joint stiffness caused by arthritis, bursitis, and gout attacks." - Anonymous Online Contributor
Unverified Answer
Is Naprosyn a narcotic?
"Naprosyn is a non-steroidal anti-inflammatory drug, but it works in a similar way to a narcotic to relieve [back pain](https://www.withpower.com/clinical-trials/back-pain), bursitis, spondylitis, dental pain and menstrual cramps." - Anonymous Online Contributor
Unverified Answer
Is Naprosyn and ibuprofen the same?
"There are some key differences between ibuprofen and naproxen even though they are very similar. For example, ibuprofen does not provide pain relief for as long as naproxen. This means that you would not have to take naproxen as often." - Anonymous Online Contributor
Unverified Answer