Myrbetriq

Overactive Bladder Syndrome, Neurogenic Detrusor Overactivity, Obesity

Treatment

2 FDA approvals

20 Active Studies for Myrbetriq

Treatment for

Overactive Bladder Syndrome

What is Myrbetriq

MirabegronThe Generic name of this drug

Treatment SummaryMirabegron is a medication used to treat urinary frequency and incontinence. It works by relaxing the bladder muscles, and is different from other similar medications because it doesn’t have the same side effects. Mirabegron was first approved by the FDA in 2012 and is also used in other countries. It can also be used in combination with other medications for more serious cases, and an extended-release granule formulation was recently approved for children with neurogenic detrusor overactivity.

Myrbetriqis the brand name

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Myrbetriq Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Myrbetriq

Mirabegron

2012

Approved as Treatment by the FDA

Mirabegron, also known as Myrbetriq, is approved by the FDA for 2 uses which include Overactive Bladder Syndrome (OABS) and Overactive Bladder Syndrome .

Overactive Bladder Syndrome (OABS)

Used to treat Overactive Bladder Syndrome (OABS) in combination with Solifenacin

Overactive Bladder Syndrome

Used to treat Overactive Bladder Syndrome (OABS) in combination with Solifenacin

Effectiveness

How Myrbetriq Affects PatientsMirabegron works by making the bladder muscles relax, allowing it to hold more and reducing any urgency to urinate. However, it can raise both blood pressure and heart rate, so it should be used with caution in those with severe hypertension or other conditions where these increases could be dangerous. It should also be used with care in patients with bladder outlet obstruction, as it has been linked to urinary retention.

How Myrbetriq works in the bodyMirabegron is a medication that relaxes the muscles of the bladder. This increases the bladder's capacity, making it easier to hold in urine and reducing the feeling of needing to go often.

When to interrupt dosage

The prescribed dosage of Myrbetriq is contingent upon the recognized condition, including Neurogenic Detrusor Overactivity, Overactive Bladder Syndrome and a weight of at least 35 kg. The measure of dosage alters, dependent upon the technique of delivery (e.g. Granule, for suspension, extended release - Oral or Tablet, extended release - Oral) as indicated in the table beneath.

Condition

Dosage

Administration

Overactive Bladder Syndrome

, 25.0 mg, 50.0 mg, 8.0 mg/mL

Oral, , Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Granule, for suspension, extended release - Oral, Granule, for suspension, extended release

Neurogenic Detrusor Overactivity

, 25.0 mg, 50.0 mg, 8.0 mg/mL

Obesity

, 25.0 mg, 50.0 mg, 8.0 mg/mL

Warnings

Myrbetriq Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Mirabegron may interact with Pulse Frequency

There are 20 known major drug interactions with Myrbetriq.

Common Myrbetriq Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The serum concentration of Abemaciclib can be increased when it is combined with Mirabegron.

Axitinib

Major

The serum concentration of Axitinib can be increased when it is combined with Mirabegron.

Bendamustine

Major

The serum concentration of Bendamustine can be increased when it is combined with Mirabegron.

Binimetinib

Major

The serum concentration of Binimetinib can be increased when it is combined with Mirabegron.

Cabazitaxel

Major

The serum concentration of Cabazitaxel can be increased when it is combined with Mirabegron.

Myrbetriq Toxicity & Overdose RiskIf the recommended maximum dose of Diovan is exceeded (up to 400mg for healthy volunteers), the individual may experience palpitations and a faster heart rate. Long-term overdosing can produce similar symptoms and a rise in systolic blood pressure. If someone overdoses on Diovan, standard treatments should be administered alongside ECG monitoring.

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Myrbetriq Novel Uses: Which Conditions Have a Clinical Trial Featuring Myrbetriq?

33 active clinical trials are examining the potential of Myrbetriq for treating Neurogenic Detrusor Overactivity, Pediatric Subjects with Weight at least 35 kg and Overactive Bladder Syndrome.

Condition

Clinical Trials

Trial Phases

Obesity

0 Actively Recruiting

Overactive Bladder Syndrome

36 Actively Recruiting

Not Applicable, Phase 3, Phase 4, Phase 1, Phase 2

Neurogenic Detrusor Overactivity

3 Actively Recruiting

Phase 2, Phase 3, Phase 1

Myrbetriq Reviews: What are patients saying about Myrbetriq?

5Patient Review

4/20/2022

Myrbetriq for Overactive Bladder

When given oxybutynin alongside this medication, I saw the best results. No leakage or urgency. My blood pressure was already normal, but it increased slightly. However, it's nothing to worry about in comparison to the massive improvements in quality of life and confidence that these two medications have brought me.

5Patient Review

7/26/2022

Myrbetriq for Overactive Bladder

Myretig has been an amazing medication for me. After my hysterectomy, I developed OB and was constantly leaking. This medication has helped me to be dry most of the day and urinate normally.

3.7Patient Review

8/16/2020

Myrbetriq for Frequent Urination

Unfortunately, I experienced some pretty severe chest pains about ten days after using this medication. I ended up in atrial fibrillation and needed a pacemaker.

3.7Patient Review

6/21/2020

Myrbetriq for Needing to Urinate Immediately

I no longer have to wake up to use the restroom as frequently, but when I do have to go, it's an immediate emergency. Additionally, I don't care for the smell of my urine now and my back pains seem more intense.

3.3Patient Review

8/22/2022

Myrbetriq for Overactive Bladder

I experienced a lot of side effects from the medication, including nausea, dizziness, headaches, and elevated blood pressure. I'm not sure if the benefits were worth it.

View All Reviews

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Patient Q&A Section about myrbetriq

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does Myrbetriq make you pee more?

"Myrbetriq can help children with NDO by increasing the capacity of their bladder and reducing the number of incontinence episodes."

Answered by AI

What is the side effects of Myrbetriq?

"The most common side effects of MYRBETRIQ are high blood pressure, nasopharyngitis, urinary tract infection, and headache."

Answered by AI

What is Myrbetriq used to treat?

"This medication is used to treat certain bladder problems including overactive bladder and neurogenic detrusor overactivity. Overactive bladder is a bladder storage problem while neurogenic detrusor overactivity is a bladder control condition caused by issues with the brain, spinal cord or nerves."

Answered by AI

What symptoms does Myrbetriq treat?

"The detrusor muscle is the muscle that contracts and relaxes to hold and release urine.

Myrbetriq may be prescribed to adults with OAB in order to treat urinary frequency, urgency, or incontinence. OAB is caused by the detrusor muscle in the bladder contracting too often or without warning. The detrusor muscle is the muscle that contracts and relaxes to hold and release urine."

Answered by AI

Clinical Trials for Myrbetriq

Have you considered Myrbetriq clinical trials? We made a collection of clinical trials featuring Myrbetriq, we think they might fit your search criteria.

Have you considered Myrbetriq clinical trials? We made a collection of clinical trials featuring Myrbetriq, we think they might fit your search criteria.