What is Myrbetriq
MirabegronThe Generic name of this drug
Treatment SummaryMirabegron is a medication used to treat urinary frequency and incontinence. It works by relaxing the bladder muscles, and is different from other similar medications because it doesn’t have the same side effects. Mirabegron was first approved by the FDA in 2012 and is also used in other countries. It can also be used in combination with other medications for more serious cases, and an extended-release granule formulation was recently approved for children with neurogenic detrusor overactivity.
Myrbetriqis the brand name
Myrbetriq Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Myrbetriq
Mirabegron
2012
8
Approved as Treatment by the FDA
Mirabegron, also known as Myrbetriq, is approved by the FDA for 1 uses which include Overactive Bladder Syndrome .Overactive Bladder Syndrome
Used to treat Overactive Bladder Syndrome (OABS) in combination with Solifenacin
Effectiveness
How Myrbetriq Affects PatientsMirabegron works by making the bladder muscles relax, allowing it to hold more and reducing any urgency to urinate. However, it can raise both blood pressure and heart rate, so it should be used with caution in those with severe hypertension or other conditions where these increases could be dangerous. It should also be used with care in patients with bladder outlet obstruction, as it has been linked to urinary retention.
How Myrbetriq works in the bodyMirabegron is a medication that relaxes the muscles of the bladder. This increases the bladder's capacity, making it easier to hold in urine and reducing the feeling of needing to go often.
When to interrupt dosage
The prescribed dosage of Myrbetriq is contingent upon the recognized condition, including Neurogenic Detrusor Overactivity, Overactive Bladder Syndrome and a weight of at least 35 kg. The measure of dosage alters, dependent upon the technique of delivery (e.g. Granule, for suspension, extended release - Oral or Tablet, extended release - Oral) as indicated in the table beneath.Condition
Dosage
Administration
weight at least 35 kg
50.0 mg, , 8.0 mg/mL, 25.0 mg
Granule, for suspension, extended release - Oral, Tablet, extended release - Oral, Tablet, extended release, Granule, for suspension, extended release, Oral, , Tablet, film coated, extended release - Oral, Tablet, film coated, extended release
Neurogenic Detrusor Overactivity
50.0 mg, , 8.0 mg/mL, 25.0 mg
Granule, for suspension, extended release - Oral, Tablet, extended release - Oral, Tablet, extended release, Granule, for suspension, extended release, Oral, , Tablet, film coated, extended release - Oral, Tablet, film coated, extended release
Overactive Bladder Syndrome
50.0 mg, , 8.0 mg/mL, 25.0 mg
Granule, for suspension, extended release - Oral, Tablet, extended release - Oral, Tablet, extended release, Granule, for suspension, extended release, Oral, , Tablet, film coated, extended release - Oral, Tablet, film coated, extended release
Warnings
Myrbetriq ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Mirabegron may interact with Toxoplasma Infections
Common Myrbetriq Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The serum concentration of Abemaciclib can be increased when it is combined with Mirabegron.
Axitinib
Major
The serum concentration of Axitinib can be increased when it is combined with Mirabegron.
Bendamustine
Major
The serum concentration of Bendamustine can be increased when it is combined with Mirabegron.
Binimetinib
Major
The serum concentration of Binimetinib can be increased when it is combined with Mirabegron.
Cabazitaxel
Major
The serum concentration of Cabazitaxel can be increased when it is combined with Mirabegron.
Myrbetriq Toxicity & Overdose RiskIf the recommended maximum dose of Diovan is exceeded (up to 400mg for healthy volunteers), the individual may experience palpitations and a faster heart rate. Long-term overdosing can produce similar symptoms and a rise in systolic blood pressure. If someone overdoses on Diovan, standard treatments should be administered alongside ECG monitoring.
Myrbetriq Novel Uses: Which Conditions Have a Clinical Trial Featuring Myrbetriq?
33 active clinical trials are examining the potential of Myrbetriq for treating Neurogenic Detrusor Overactivity, Pediatric Subjects with Weight at least 35 kg and Overactive Bladder Syndrome.Condition
Clinical Trials
Trial Phases
weight at least 35 kg
0 Actively Recruiting
Neurogenic Detrusor Overactivity
1 Actively Recruiting
Phase 3
Overactive Bladder Syndrome
33 Actively Recruiting
Not Applicable, Phase 3, Phase 4
Myrbetriq Reviews: What are patients saying about Myrbetriq?
5Patient Review
4/20/2022 When given oxybutynin alongside this medication, I saw the best results. No leakage or urgency. My blood pressure was already normal, but it increased slightly. However, it's nothing to worry about in comparison to the massive improvements in quality of life and confidence that these two medications have brought me.
5Patient Review
7/26/2022 Myretig has been an amazing medication for me. After my hysterectomy, I developed OB and was constantly leaking. This medication has helped me to be dry most of the day and urinate normally.
3.7Patient Review
8/16/2020 Unfortunately, I experienced some pretty severe chest pains about ten days after using this medication. I ended up in atrial fibrillation and needed a pacemaker.
3.7Patient Review
6/21/2020 I no longer have to wake up to use the restroom as frequently, but when I do have to go, it's an immediate emergency. Additionally, I don't care for the smell of my urine now and my back pains seem more intense.
3.3Patient Review
8/22/2022 I experienced a lot of side effects from the medication, including nausea, dizziness, headaches, and elevated blood pressure. I'm not sure if the benefits were worth it.
3Patient Review
2/19/2020 I've been using Myrbetriq for a little over three months now. It's helped somewhat, but I still feel the constant urge to urinate. Additionally, I've experienced dry eyes and lower back pain. I'm going to give it a few more weeks before trying Botox in the bladder.
2.7Patient Review
2/25/2022 I lost half of my hair while using this medication, which was a huge and very unexpected side effect. It's been slowly growing back, but I'll never get back the volume or thickness that I had before.
2.3Patient Review
3/17/2022 I had some really severe and uncomfortable side effects while taking this medication. I'm glad I did my own research and stopped before things got worse.
2Patient Review
10/18/2021 I saw no difference after taking this medication for four weeks. It was a waste of money.
2Patient Review
2/12/2022 I've been taking the 50mg pill daily for a month now with no reduction in how many times I have to urinate at night.
2Patient Review
4/21/2022 I have experienced some bleeding since starting this medication.
2Patient Review
1/17/2021 I didn't have a good experience with this medication because of the severe side effects I experienced, like nausea and dizziness. My blood pressure also increased, which is not ideal for someone who already has low blood pressure.
2Patient Review
2/17/2021 It's had some effect, but not as much as I would like given the price.
1.7Patient Review
7/16/2021 I started having memory problems after only five days of taking this drug. I stopped immediately, but there has been no improvement. The only other possible explanations are that I had undiagnosed COVID, which can sometimes cause this side effect, or it was from a slight increase in my Moclobimide dose. But I have taken Moclobimide at that dose before without any problems, and I tested negative for Covid.
Patient Q&A Section about myrbetriq
Does Myrbetriq make you pee more?
"Myrbetriq can help children with NDO by increasing the capacity of their bladder and reducing the number of incontinence episodes." - Anonymous Online Contributor
Unverified Answer
What is the side effects of Myrbetriq?
"The most common side effects of MYRBETRIQ are high blood pressure, nasopharyngitis, urinary tract infection, and headache." - Anonymous Online Contributor
Unverified Answer
What is Myrbetriq used to treat?
"This medication is used to treat certain bladder problems including overactive bladder and neurogenic detrusor overactivity. Overactive bladder is a bladder storage problem while neurogenic detrusor overactivity is a bladder control condition caused by issues with the brain, spinal cord or nerves." - Anonymous Online Contributor
Unverified Answer
What symptoms does Myrbetriq treat?
"The detrusor muscle is the muscle that contracts and relaxes to hold and release urine.
Myrbetriq may be prescribed to adults with OAB in order to treat urinary frequency, urgency, or incontinence. OAB is caused by the detrusor muscle in the bladder contracting too often or without warning. The detrusor muscle is the muscle that contracts and relaxes to hold and release urine." - Anonymous Online Contributor
Unverified Answer