Micardis Hct

unable to take ACE inhibitors, prophylaxis of cardiovascular event, Congestive Heart Failure + 5 more
Treatment
6 FDA approvals
20 Active Studies for Micardis Hct

What is Micardis Hct

TelmisartanThe Generic name of this drug
Treatment SummaryHydrochlorothiazide is a common medication used to treat swelling and high blood pressure. It works by helping the body get rid of extra water and salt. It has been available since 1959 and is often used in combination with other medications like ACE inhibitors or angiotensin II receptor blockers. However, it is becoming less popular as other medications become available.
Micardis HCTis the brand name
Micardis Hct Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Micardis HCT
Telmisartan
2000
182

Approved as Treatment by the FDA

Telmisartan, also known as Micardis HCT, is approved by the FDA for 6 uses including Hypertension and unable to take ACE inhibitors .
Hypertension
Used to treat blood pressure inadequately controlled with monotherapy in combination with Amlodipine
unable to take ACE inhibitors
prophylaxis of cardiovascular event
Cardiovascular Events
Hypertensive disease
Helps manage High Blood Pressure (Hypertension)
no initial therapy
Used to treat no initial therapy in combination with Amlodipine

Effectiveness

How Micardis Hct Affects PatientsHydrochlorothiazide stops the body from reabsorbing salt and water in the kidneys, increasing the amount of water released in urine. The right dose for each individual can differ, but is usually between 25-100mg. People with kidney or liver problems should be careful when taking this drug.
How Micardis Hct works in the bodyHydrochlorothiazide works to reduce water reabsorption in the kidneys. It is transported from the bloodstream into epithelial cells of the distal convoluted tubule by special molecules called transporters. Then, it is sent to the lumen of the tubule by another molecule called MRP4. In the distal convoluted tubule, sodium is typically reabsorbed and pumped into the interstitium, creating a concentration gradient that draws water back into the cells. Hydrochlorothiazide blocks this process by inhibiting a transporter, SLC12A3, which reduces the concentration gradient and prevents the reabsorption

When to interrupt dosage

The advisable dosage of Micardis Hct depends on the identified condition, including Antepartum magnesium sulfate prophylaxis, blood pressure inadequately managed with monotherapy and antihypertensives. The dosage also fluctuates in correlation to the technique of delivery (e.g. Tablet, coated - Oral or Oral) outlined in the table below.
Condition
Dosage
Administration
unable to take ACE inhibitors
, 40.0 mg, 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, multilayer, Tablet, multilayer - Oral
prophylaxis of cardiovascular event
, 40.0 mg, 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, multilayer, Tablet, multilayer - Oral
Congestive Heart Failure
, 40.0 mg, 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, multilayer, Tablet, multilayer - Oral
Hypertensive disease
, 40.0 mg, 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, multilayer, Tablet, multilayer - Oral
Diabetic Nephropathies
, 40.0 mg, 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, multilayer, Tablet, multilayer - Oral
Cardiovascular Events
, 40.0 mg, 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, multilayer, Tablet, multilayer - Oral
no initial therapy
, 40.0 mg, 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, multilayer, Tablet, multilayer - Oral
Hypertension
, 40.0 mg, 80.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, multilayer, Tablet, multilayer - Oral

Warnings

Micardis Hct has two contraindications. It should not be taken concomitantly with the conditions in the table below.Micardis Hct Contraindications
Condition
Risk Level
Notes
Type 2 Diabetes
Do Not Combine
There are 20 known major drug interactions with Micardis Hct.
Common Micardis Hct Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Telmisartan.
Amifostine
Major
Telmisartan may increase the hypotensive activities of Amifostine.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Telmisartan.
Clomipramine
Major
The metabolism of Clomipramine can be decreased when combined with Telmisartan.
Cyclophosphamide
Major
The metabolism of Cyclophosphamide can be decreased when combined with Telmisartan.
Micardis Hct Toxicity & Overdose RiskThe lowest toxic dose of hydrochlorothiazide in mice and rats is greater than 10g/kg. Those who overdose on hydrochlorothiazide may experience low potassium, chloride, or sodium levels in the blood, which can be treated with fluids and electrolytes. If the patient is experiencing low blood pressure, they may need to be given medications to raise their blood pressure, and oxygen may be necessary if they have difficulty breathing.
image of a doctor in a lab doing drug, clinical research

Micardis Hct Novel Uses: Which Conditions Have a Clinical Trial Featuring Micardis Hct?

158 active clinical trials are underway to assess the potential of Micardis Hct in alleviating Cirrhosis, Edema, and Congestive Heart Failure.
Condition
Clinical Trials
Trial Phases
unable to take ACE inhibitors
0 Actively Recruiting
Hypertension
294 Actively Recruiting
Not Applicable, Phase 2, Phase 1, Phase 3, Early Phase 1, Phase 4
Congestive Heart Failure
176 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Phase 3, Early Phase 1
prophylaxis of cardiovascular event
0 Actively Recruiting
Cardiovascular Events
4 Actively Recruiting
Not Applicable
no initial therapy
0 Actively Recruiting
Hypertensive disease
23 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Diabetic Nephropathies
0 Actively Recruiting

Micardis Hct Reviews: What are patients saying about Micardis Hct?

5Patient Review
5/12/2017
Micardis Hct for High Blood Pressure
I've been taking this medication for a while now and my blood pressure is great.
5Patient Review
11/9/2018
Micardis Hct for High Blood Pressure
I've been on this medication for ten days now and I haven't experienced any negative side effects. This is in contrast to many other medications I've tried, which have had awful side effects that made them unusable.
4.3Patient Review
6/25/2014
Micardis Hct for High Blood Pressure
I've been taking this medication for three years now and it's working great. I only need half a tablet, which is nice because it makes the supply last longer. The only side effect I experienced was some pain in my right leg, but that went away after a few days.
4Patient Review
6/14/2012
Micardis Hct for High Blood Pressure
I had a chronic cough that made me very self-conscious. I was really hesitant to try this treatment, but it ended up helping me so much! Not only did it get rid of my cough, but I also lost weight!
3.7Patient Review
10/17/2012
Micardis Hct for High Blood Pressure
This treatment really helped me with my erectile dysfunction. I was a bit worried at first, but it worked great!
View All Reviews
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about micardis hct

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Micardis a good blood pressure medicine?

"Telmisartan is an effective blood pressure-lowering medication that can help protect your heart and kidneys."

Answered by AI

What are the side effects of Micardis HCT?

"Upper respiratory tract infections can cause sinus pain and congestion, as well as a sore throat. Other symptoms include dizziness, fatigue, flu-like symptoms, back pain, diarrhea, and nausea."

Answered by AI

What is Micardis HCT used for?

"It works by relaxing blood vessels so that blood can flow more easily. Hydrochlorothiazide is a "water pill" (diuretic) that causes you to make more urine, which helps your body get rid of excess water.

This medication is used to treat high blood pressure by lowering it. This can prevent strokes, heart attacks, and kidney problems. The medication is a combination of two drugs, telmisartan and hydrochlorothiazide. Telmisartan relaxes blood vessels so blood can flow more easily and hydrochlorothiazide is a diuretic that helps remove excess water from the body."

Answered by AI

When should I take Micardis HCT?

"You will typically start by taking Micardis HCT at a dose of 80 mg/12.5 mg (telmisartan/hydrochlorothiazide) orally once per day. If you need to lower your blood pressure more, your healthcare provider can increase your dose to 160 mg/25 mg (telmisartan/hydrochlorothiazide) once per day."

Answered by AI

Clinical Trials for Micardis Hct

Have you considered Micardis Hct clinical trials? We made a collection of clinical trials featuring Micardis Hct, we think they might fit your search criteria.
Have you considered Micardis Hct clinical trials? We made a collection of clinical trials featuring Micardis Hct, we think they might fit your search criteria.
Have you considered Micardis Hct clinical trials? We made a collection of clinical trials featuring Micardis Hct, we think they might fit your search criteria.
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