Study Summary
This trial will study 66 seniors over 3 years to understand why the flu vaccine is less effective in older adults. Blood, nasal, and stool samples will be collected at 16 study visits.
- Flu Vaccine, Flu
- Aging
- Dendritic Cell
- Vaccine Response
Treatment Effectiveness
Effectiveness Progress
Study Objectives
3 Primary · 12 Secondary · Reporting Duration: Baseline, Day1, Day 7, Day 35, Day 180
Trial Safety
Safety Progress
Trial Design
1 Treatment Group
Healthy Older Adults
1 of 1
Experimental Treatment
66 Total Participants · 1 Treatment Group
Primary Treatment: Flu Vaccine (Year 3) · No Placebo Group · Phase 4
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 65+ · All Participants · 9 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
What is the chief aim of this research endeavor?
"The primary purpose of this investigation, which will be assessed over the course of Baseline, Day 35 and Day 180 is to assess Change in Antibody Responses to Influenza Vaccine Year Three. Additionally, secondary objectives include establishing the Number of chromatin accessibility regions activated in response to Influenza Vaccine in Year Two and Year Three using snATAC-seq as well as determining how many genes are upregulated by both FLUAD and CDC recommended FDA approved influenza vaccinations via RNA-seq and scRNA-seq respectively." - Anonymous Online Contributor
What is the sample size of participants involved in this research?
"That is correct. According to clinicaltrials.gov, this research project has been ongoing since August 31st 2022 and is still recruiting participants as of September 15th 2022. 66 individuals are sought from a single site for the trial." - Anonymous Online Contributor
To what extent is Year 3 of the Flu Vaccine detrimental to those receiving it?
"The safety of Year 3 Flu Vaccine was given a rating of 3 due to the various clinical trials that have approved this treatment." - Anonymous Online Contributor
Are there any unfilled slots in this clinical experiment?
"Clinical trials.gov confirms that this clinical research is presently recruiting participants, having been first posted on August 31st 2022 and last modified September 15th 2022." - Anonymous Online Contributor