BreEStim for Motor Recovery After Stroke
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine if a new treatment called BreEStim, which uses breathing to control electrical stimulation, can reduce finger stiffness and improve hand function in stroke survivors. It compares BreEStim to another technique, EStim, which also uses electrical stimulation. Suitable candidates for this trial have experienced a stable stroke for at least six months, have noticeable finger stiffness, and have no vision or hearing issues.
As an unphased trial, this study provides a unique opportunity to explore innovative treatments that could enhance recovery and quality of life after a stroke.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are currently adjusting medications that affect muscle tone, like baclofen.
What prior data suggests that BreEStim is safe for motor recovery after stroke?
Research shows that BreEStim, a type of electrical stimulation controlled by breathing, is under study for its effects on stroke recovery. This method uses gentle electrical currents to target specific muscles, and similar techniques have been used in various muscle therapies. Although specific safety data on BreEStim is limited, electrical stimulation therapies are generally well-tolerated by many people.
If BreEStim were in a later trial phase, more information about its safety would be available. However, since it is in an early stage, a complete safety profile is not yet established. Still, the widespread use of electrical stimulation in other treatments suggests it is likely safe for many people. Participants should discuss any concerns with their doctors.12345Why are researchers excited about this trial?
Researchers are excited about BreEStim because it introduces a novel approach to stroke recovery by combining voluntary breathing with transcutaneous electrical nerve stimulation (EStim). This method leverages the natural rhythm of breathing to potentially enhance nerve stimulation, which could improve motor recovery more effectively than traditional methods like physical therapy alone. Unlike conventional treatments, BreEStim offers a non-invasive and potentially faster way to restore motor function, providing hope for better outcomes in stroke rehabilitation.
What evidence suggests that BreEStim is effective for motor recovery after stroke?
Research has shown that BreEStim, which combines breathing exercises with gentle electrical nerve stimulation, might improve hand movement and reduce finger stiffness after a stroke. In this trial, participants will receive either BreEStim or EStim, which involves transcutaneous electrical nerve stimulation. Studies have found that electrical stimulation can significantly enhance movement control in stroke patients. Those who have used these methods alongside regular therapy have experienced noticeable improvements in recovery. This suggests that BreEStim could benefit individuals with moderate difficulties from a long-term stroke. While researchers continue to collect data, early results offer hope for those aiming to regain hand function after a stroke.12678
Who Is on the Research Team?
Sheng Li, MD, PhD
Principal Investigator
University of Texas
Are You a Good Fit for This Trial?
This trial is for individuals who have had a stroke at least 6 months ago, resulting in moderate hand impairment due to muscle stiffness. They must be medically stable and not have visual, hearing or cognitive impairments, severe lung diseases, recent botulinum toxin or phenol injections in the arm/fingers, pacemakers, or be pregnant.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive BreEStim or EStim intervention for finger flexor spasticity reduction and hand function improvement
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- BreEStim
Find a Clinic Near You
Who Is Running the Clinical Trial?
The University of Texas Health Science Center, Houston
Lead Sponsor