Your session is about to expire
What is Metozolv Odt
MetoclopramideThe Generic name of this drug
Treatment SummaryMetoclopramide is a medication used to treat nausea, vomiting, and other symptoms of diabetic gastroparesis. It can also be used to prevent nausea or vomiting associated with chemotherapy or certain types of surgeries or tests. It is unique in that it does not increase stomach acid production. Metoclopramide comes in tablet form, liquid form, or can be given intravenously. It was first approved by the FDA in 1980.
Metoclopramideis the brand name
Metozolv Odt Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Metoclopramide
Metoclopramide
1985
199
Approved as Treatment by the FDA
Metoclopramide, commonly known as Metoclopramide, is approved by the FDA for 3 uses including Failed conventional therapy and Gastroesophageal Reflux Disease (GERD) .Failed conventional therapy
Gastroesophageal Reflux Disease (GERD)
Gastroparesis
Effectiveness
How Metozolv Odt Affects PatientsMetoclopramide helps to empty the stomach by reducing the pressure of the lower esophageal sphincter. It also helps to reduce nausea and vomiting. This drug will speed up digestion without increasing the amount of acid, bile, or enzymes that are produced. However, it should not be taken for more than 12 weeks as it can cause side effects such as tardive dyskinesia, dystonia, and akathisia.
How Metozolv Odt works in the bodyMetoclopramide helps stop nausea and vomiting by blocking certain receptors in the brain. It also helps speed up digestion by boosting the release of a chemical called acetylcholine, which helps relax the muscles in your stomach and intestines. Metoclopramide also blocks dopamine receptors, which usually help relax the gastrointestinal tract.
When to interrupt dosage
The measure of Metozolv Odt is contingent upon the diagnosed affliction, including Nausea, Intubation (method) and Gastroesophageal Reflux Disease (GERD). The amount additionally fluctuates as per the procedure of administration (e.g. Spray or Tablet, orally disintegrating) detailed in the table beneath.Condition
Dosage
Administration
Pharmacotherapy
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
Nausea
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
prophylaxis of Hiccups
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
Failed conventional therapy
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
Hyperacidity
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
meteorism
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
Acute Coryza
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
Pharmacotherapy
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
Gastroparesis
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
Nausea
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
Aerophagy
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
Indigestion
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
Gastric Acid
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
Intubation (procedure)
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
gastric emptying for radiologic procedures
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
Therapeutic procedure
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
Nausea
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
Gastroparesis
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
Gastrointestinal distress
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
Flatulence
10.0 mg, , 5.0 mg, 5.0 mg/mL, 10.0 mg/mL, 1.0 mg/mL, 1.0 mg, 9.0 mg/mL, 1500.0 mg/mL
, Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intravenous, Injection - Intravenous, Liquid, Liquid - Intramuscular; Intravenous, Syrup, Syrup - Oral, Liquid - Oral, Liquid - Intravenous, Injection, solution - Intravenous, Oral; Topical, Kit, Kit - Oral; Topical, Spray, Spray - Nasal, Nasal, Solution - Intramuscular; Intravenous
Warnings
Metozolv Odt ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Metoclopramide may interact with Pulse Frequency
Mechanical Intestinal Obstruction
Do Not Combine
Gastrointestinal Hemorrhage
Do Not Combine
Gastrointestinal Perforation
Do Not Combine
catecholamine-releasing paragangliomas
Do Not Combine
Tardive Dyskinesia
Do Not Combine
Pharmaceutical Preparations
Do Not Combine
Pheochromocytomas
Do Not Combine
Parkinson's Disease
Do Not Combine
Depression
Do Not Combine
Epilepsies
Do Not Combine
Gastrectomy
Do Not Combine
Dystonia
Do Not Combine
Feeling suicidal (finding)
Do Not Combine
Common Metozolv Odt Drug Interactions
Drug Name
Risk Level
Description
Acepromazine
Major
The risk or severity of adverse effects can be increased when Metoclopramide is combined with Acepromazine.
Aceprometazine
Major
The risk or severity of adverse effects can be increased when Metoclopramide is combined with Aceprometazine.
Acetophenazine
Major
The risk or severity of adverse effects can be increased when Metoclopramide is combined with Acetophenazine.
Alimemazine
Major
The risk or severity of adverse effects can be increased when Metoclopramide is combined with Alimemazine.
Amisulpride
Major
The risk or severity of adverse effects can be increased when Metoclopramide is combined with Amisulpride.
Metozolv Odt Toxicity & Overdose RiskThe lowest toxic dose of metoclopramide for rats is 750 mg/kg. Overdosing on metoclopramide can cause drowsiness, confusion, and movement disorders. Medications to treat Parkinson's disease, anticholinergic drugs, or antihistamines with anticholinergic properties may help reduce these symptoms. In infants, an overdose of metoclopramide can cause seizures, movement disorders, and a lethargic state. Methemoglobinemia (a condition where the blood cannot carry enough oxygen) has also been linked to overdoses in newborns, which can be treated with methylene
Metozolv Odt Novel Uses: Which Conditions Have a Clinical Trial Featuring Metozolv Odt?
Research is currently being conducted for 113 studies to evaluate the potential of Metozolv Odt in providing Migraine, Nausea and Pharmacotherapy relief.Condition
Clinical Trials
Trial Phases
Gastric Motility Disorder
0 Actively Recruiting
Migraine
52 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1
Nausea
2 Actively Recruiting
Not Applicable, Phase 4
Acute Coryza
0 Actively Recruiting
Pharmacotherapy
0 Actively Recruiting
Nausea
0 Actively Recruiting
Gastric Acid
0 Actively Recruiting
Gastroparesis
4 Actively Recruiting
Not Applicable, Phase 2
Aerophagy
0 Actively Recruiting
Nausea
0 Actively Recruiting
Flatulence
0 Actively Recruiting
Intubation (procedure)
0 Actively Recruiting
Hiccups
0 Actively Recruiting
Pharmacotherapy
1 Actively Recruiting
Phase 4
Gastroparesis
21 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 2
Gastroesophageal Reflux Disease (GERD)
25 Actively Recruiting
Not Applicable, Phase 3, Phase 1, Phase 2, Phase 4
Nausea
0 Actively Recruiting
Failed conventional therapy
0 Actively Recruiting
Gastrointestinal distress
21 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3, Early Phase 1
Therapeutic procedure
0 Actively Recruiting
Metozolv Odt Reviews: What are patients saying about Metozolv Odt?
5Patient Review
7/28/2010 I've only been on this medication for a week, but it has already shown to be effective.
5Patient Review
3/12/2010 This treatment worked well for me with no side effects.
4.3Patient Review
3/3/2010 GERD caused me a lot of discomfort by creating gas bubbles in my chest/esophagus. This medication, taken half an hour before dinner, reduced my symptoms four out of five nights and allowed me to sleep uninterrupted.
Patient Q&A Section about metozolv odt
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is metoclopramide used for?
"Metoclopramide can be used to help stop you feeling or being sick if you are undergoing radiotherapy or chemotherapy, or if you are experiencing sickness due to a migraine."
Answered by AI
Is Propulsid available in the US?
"The brand name Propulsid is not available in the U.S., but there may be generic versions available."
Answered by AI
What does ODT medication?
"An orally disintegrating tablet is a type of pill that is designed to dissolve on the tongue, rather than being swallowed whole. This type of pill is available for a limited range of over-the-counter and prescription medications."
Answered by AI
What is the side effects of metoclopramide?
"Some of the symptoms of the flu include feeling very tired, weak, and dizzy. You may also have a headache, and some people experience nausea and vomiting. Diarrhea is another symptom that some people experience when they have the flu."
Answered by AI