Alternate Nostril Breathing for Morning Sickness

Overseen By Erin Wesley

Age: 18+

Sex: Female

Trial Phase: Academic

Sponsor: University of Minnesota

Disqualifiers: Severe nausea, Respiratory conditions, Anxiety, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

Duration: 1 week

What You Need to Know Before You Apply

What is the purpose of this trial?

This is a prospective, two-arm, non-blinded randomized controlled study designed to evaluate the effects of a one-week alternate nostril breathing (ANB) intervention on nausea and vomiting severity in pregnant individuals during their first trimester.

Who Is on the Research Team?

Shilpa Babbar

Principal Investigator

University of Minnesota

Are You a Good Fit for This Trial?

This trial is for English-speaking pregnant individuals aged 18 or older, in their first trimester (6-12 weeks), who have mild to moderate nausea and vomiting. They must be able to confirm pregnancy via last period or ultrasound.

Inclusion Criteria

I have mild to moderate nausea and vomiting during pregnancy.

I am pregnant and 18 years or older.

I am pregnant, between 6 to 12 weeks along, confirmed by a doctor.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 week

Treatment

Participants perform alternate nostril breathing (ANB) 3 times per day for 5-10 minutes per session over a 7-day period

1 week

1 visit (in-person) for orientation

Follow-up

Participants are monitored for changes in nausea and vomiting severity using the PUQE score

1 week

What Are the Treatments Tested in This Trial?

Interventions

• Alternate Nostril Breathing

Trial Overview

The study tests Alternate Nostril Breathing (ANB) as a treatment for first-trimester nausea and vomiting. Participants will be randomly assigned to either practice ANB for one week or not, to see if it reduces the severity of symptoms.

How Is the Trial Designed?

Group I: Alternate Nostril Breathing Active Control 1 Intervention

Participants in the intervention group will receive a brief orientation via a research team member at the time of randomization on alternate nostril breathing (ANB) and then be provided with a written and video-based instructional guide. They will be instructed to perform ANB 3 times per day for 5-10 minutes per session over a 7-day period and document their sessions in a daily symptom diary. The 7-day period will begin the following day after enrollment to allow for a full day of intervention implementation (Day 1-7).

Group II: Usual Care Only Active Control 1 Intervention

This group will receive usual care and complete a daily symptom diary for Day 1-7.

Who Is Running the Clinical Trial?

University of Minnesota

Lead Sponsor

Trials

1,459

Recruited

1,623,000+