What is Mavik
TrandolaprilThe Generic name of this drug
Treatment SummaryTrandolapril is a medication that belongs to the ACE inhibitor class. It works by blocking an enzyme in the body called angiotensin-converting enzyme (ACE), which helps regulate blood pressure. This drug is used to treat mild to moderate high blood pressure, improve heart function after a heart attack, treat congestive heart failure, and slow down kidney disease progression in people with diabetes and kidney problems.
Mavikis the brand name
Mavik Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Mavik
Trandolapril
1996
70
Effectiveness
How Mavik Affects PatientsTrandolapril works by blocking an enzyme (ACE) in the body that helps control blood pressure. ACE is part of the RAAS system, which helps to regulate and maintain healthy blood pressure by releasing hormones like aldosterone, vasopressin, and antidiuretic hormone. These hormones then help the body to reabsorb sodium, potassium, and water from the kidneys, which leads to increased blood pressure. Trandolapril prevents this process from happening, which lowers blood pressure and relaxes the muscles of the arteries. It also helps boost levels of bradykinin, a naturally occurring chemical that can
How Mavik works in the bodyACE inhibitors work by blocking two different types of ACE proteins - one found in the body and one found in the testicles. The body-found ACE protein has two parts that do different things - one helps regulate blood pressure, and the other helps with the growth and development of blood cells. Trandolaprilat, the active form of trandolapril, blocks both parts of this ACE protein. This reduces the amount of ACE molecules in the body and also increases renin activity, which helps to reduce blood pressure.
When to interrupt dosage
The prescribed dosage of Mavik is contingent upon the determined condition, including Heart Attack, Left Ventricular Dysfunction and Hypertensive disease. The amount of dosage fluctuates, contingent upon the method of delivery indicated in the table below.Condition
Dosage
Administration
Heart Attack
, 1.0 mg, 4.0 mg, 2.0 mg, 0.5 mg
Capsule - Oral, , Tablet, film coated, extended release, Tablet - Oral, Tablet, film coated, extended release - Oral, Capsule, Oral, Tablet, extended release - Oral, Tablet, extended release, Tablet
Left Ventricular Dysfunction
, 1.0 mg, 4.0 mg, 2.0 mg, 0.5 mg
Capsule - Oral, , Tablet, film coated, extended release, Tablet - Oral, Tablet, film coated, extended release - Oral, Capsule, Oral, Tablet, extended release - Oral, Tablet, extended release, Tablet
Hypertensive disease
, 1.0 mg, 4.0 mg, 2.0 mg, 0.5 mg
Capsule - Oral, , Tablet, film coated, extended release, Tablet - Oral, Tablet, film coated, extended release - Oral, Capsule, Oral, Tablet, extended release - Oral, Tablet, extended release, Tablet
Congestive Heart Failure
, 1.0 mg, 4.0 mg, 2.0 mg, 0.5 mg
Capsule - Oral, , Tablet, film coated, extended release, Tablet - Oral, Tablet, film coated, extended release - Oral, Capsule, Oral, Tablet, extended release - Oral, Tablet, extended release, Tablet
Warnings
Mavik ContraindicationsCondition
Risk Level
Notes
Angioedema
Do Not Combine
Type 2 Diabetes
Do Not Combine
Angioedemas, Hereditary
Do Not Combine
Common Mavik Drug Interactions
Drug Name
Risk Level
Description
Amifostine
Major
Trandolapril may increase the hypotensive activities of Amifostine.
Azathioprine
Major
The risk or severity of myelosuppression, anemia, and severe leukopenia can be increased when Trandolapril is combined with Azathioprine.
Lithium carbonate
Major
The serum concentration of Lithium carbonate can be increased when it is combined with Trandolapril.
Lithium citrate
Major
The serum concentration of Lithium citrate can be increased when it is combined with Trandolapril.
Lithium hydroxide
Major
The serum concentration of Lithium hydroxide can be increased when it is combined with Trandolapril.
Mavik Toxicity & Overdose RiskOverdosing on trandolapril can cause low blood pressure, coughing, headaches, and dizziness. Studies in mice, rats, and dogs have shown that very high doses of trandolapril may be necessary to cause death or serious health issues.
Mavik Novel Uses: Which Conditions Have a Clinical Trial Featuring Mavik?
391 active clinical trials are in progress to investigate the potential of Mavik in treating Hypertensive disease, Left Ventricular Dysfunction and Congestive Heart Failure.Condition
Clinical Trials
Trial Phases
Hypertensive disease
21 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4
Left Ventricular Dysfunction
7 Actively Recruiting
Not Applicable, Phase 4
Congestive Heart Failure
318 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Early Phase 1, Phase 4
Heart Attack
66 Actively Recruiting
Phase 4, Phase 2, Phase 3, Not Applicable, Phase 1, Early Phase 1
Mavik Reviews: What are patients saying about Mavik?
5Patient Review
7/11/2012 This drug is awesome. I'm grateful for modern medicine.
5Patient Review
3/26/2011 This drug is awesome. I'm grateful for modern medicine.
5Patient Review
7/30/2011 This drug is awesome. I love drugs.
4.7Patient Review
12/12/2018 I experience some side effects like a dry throat and increased mucus production, but it's manageable. My blood pressure has stayed normal for the four years I've been taking this medication (I upped the dosage from 1mg to 2mg).
4.3Patient Review
12/10/2012 I experienced a lot of side effects with this treatment, like dizziness, nausea, and excessive sweating. Surely there's a better solution out there.
4Patient Review
3/19/2013 My blood pressure was high, so I added Norvasc to my regiment and it helped.
3Patient Review
2/1/20113Patient Review
2/1/20113Patient Review
2/1/20113Patient Review
2/1/2011 This drug is great. It really helped me.
3Patient Review
2/4/2011 This drug is effective. I'm grateful for modern medicine.
3Patient Review
9/26/2013 This treatment caused me to have loose stool.
3Patient Review
2/4/2011 This drug is great. It helped me a lot.
2.7Patient Review
3/25/2017 I've been using this medication for a couple of years now and it worked great, until my doctor wanted to lower my blood pressure. They switched me to a higher dosage and I started experiencing some nasty side effects like dizziness, nausea, and tiredness.
2.3Patient Review
10/29/2012 The drug works well, but I've been bothered by excessive sweating since I increased the dosage to 4mg.
1.7Patient Review
8/12/2013 Unfortunately, this medication came with a laundry list of side effects for me. Headache, heavy legs, confusion, and fatigue were the main problems I experienced. Additionally, I noticed hair loss while taking this drug which was very distressing.
1.7Patient Review
11/24/2016 While I was taking Mavik, I experienced a persistent dry cough, difficulty swallowing or breathing, and hoarseness. Thankfully, these all stopped when I discontinued use of the medication.
1.7Patient Review
7/24/2017 Unfortunately, I had a severe allergic reaction after just two days of using this medication. Anaphylactic shock and prominent swelling of tongue and throat. So while it may work for others, this was unfortunately a danger for me.
Patient Q&A Section about mavik
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is mavik prescribed for?
"This medication, Trandolapril, is used to lower high blood pressure in order to prevent strokes, heart attacks, and kidney problems. It is also used to treat heart failure and improve survival rates after a heart attack."
Answered by AI
When is the best time to take mavik?
"Take the capsules as prescribed by your doctor. Your doctor may tell you to take your first dose at bedtime as you may feel dizzy when you first start taking the medication."
Answered by AI
What are the side effects of mavik?
"You may experience dizziness, drowsiness, lightheadedness, diarrhea, dry cough, or blurred vision as your body adjusts to the medication."
Answered by AI
What class of drug is mavik?
"Mavik works by relaxing blood vessels so that blood can flow more easily.
Mavik is a prescription medication that is used to treat hypertension, congestive heart failure, or left ventricular dysfunction post-MI. It may be used alone or in combination with other medications. Mavik falls under a class of drugs known as ACE inhibitors. Its mechanism of action is by relaxing blood vessels so that blood can flow more easily."
Answered by AI