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What is Luvox Cr
FluvoxamineThe Generic name of this drug
Treatment SummaryFluvoxamine is an antidepressant medication used to treat obsessive-compulsive disorder. It works by increasing the levels of serotonin, a chemical in the brain that helps regulate mood. Fluvoxamine has been used in clinical practice since 1983 and has been used to treat over 10 million people worldwide. It was approved in the US in 1994 and Japan in 1999.
Fluvoxamine Maleateis the brand name
Luvox Cr Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Fluvoxamine Maleate
Fluvoxamine
2000
76
Approved as Treatment by the FDA
Fluvoxamine, otherwise known as Fluvoxamine Maleate, is approved by the FDA for 1 uses including Depression .Depression
Helps manage Major Depressive Disorder (MDD)
Effectiveness
How Luvox Cr Affects PatientsFluvoxamine is an antidepressant medication used to treat depression, body dysmorphic disorder, and anxiety. It works by blocking serotonin (a chemical in the brain) from being taken back up by the nerve cells, allowing it to remain active in the brain and work on improving mood. In addition to targeting serotonin, Fluvoxamine does not interact with other important brain chemicals like norepinephrine, dopamine, or GABA. This helps reduce the risk of any serious side effects like dry mouth, heart problems, or confusion. Some studies have also suggested that Fluvoxamine can downregulate norepinephrine receptors in the
How Luvox Cr works in the bodyFluvoxamine helps to increase serotonin levels in the brain. It does this by blocking the reuptake of serotonin at the neuronal membrane. This prevents serotonin from being taken up and recycled, leaving more available to be used by the brain. Fluvoxamine does not interact with other receptors, such as adrenergic, muscarinic, dopamine, histamine, GABA-benzodiazepine, opiate, or 5-HT 1 or 2 receptors. It does, however, have an affinity for σ1 receptors.
When to interrupt dosage
The recommended dosage of Luvox Cr is contingent upon the identified condition, including Obsessive-Compulsive Disorder, Depression and Bulimia Nervosa. The amount of dosage varies, depending on the method of delivery (e.g. Tablet or Tablet, film coated - Oral) featured in the table below.Condition
Dosage
Administration
Obsessive-Compulsive Disorder
, 25.0 mg, 50.0 mg, 100.0 mg, 150.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
Bulimia Nervosa
, 25.0 mg, 50.0 mg, 100.0 mg, 150.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
Depression
, 25.0 mg, 50.0 mg, 100.0 mg, 150.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
Warnings
Luvox Cr ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Common Luvox Cr Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be decreased when combined with Fluvoxamine.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be decreased when combined with Fluvoxamine.
Acyclovir
Major
The metabolism of Acyclovir can be decreased when combined with Fluvoxamine.
Agomelatine
Major
The serum concentration of Agomelatine can be increased when it is combined with Fluvoxamine.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Fluvoxamine.
Luvox Cr Toxicity & Overdose RiskFluvoxamine is a type of antidepressant that has been linked to an increased risk of suicidal thoughts and behavior in children, teens, and young adults under the age of 24 in studies of depression and other mental health conditions. Fluvoxamine is not approved for use in children except for those with obsessive compulsive disorder. Common side effects may include loss of appetite, constipation, dry mouth, headache, nausea, feeling anxious, skin rash, difficulty sleeping, drowsiness, liver damage, mania, increased urination, seizures, increased sweating, tremors, or Tourette's syndrome.
Luvox Cr Novel Uses: Which Conditions Have a Clinical Trial Featuring Luvox Cr?
213 active clinical trials are assessing the potential of Luvox Cr in alleviating Obsessive-Compulsive Disorder, Bulimia Nervosa and Depressive symptoms.Condition
Clinical Trials
Trial Phases
Bulimia Nervosa
15 Actively Recruiting
Not Applicable, Phase 2, Phase 3, Early Phase 1
Obsessive-Compulsive Disorder
17 Actively Recruiting
Not Applicable, Phase 3, Phase 2
Depression
198 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Phase 4, Early Phase 1
Luvox Cr Reviews: What are patients saying about Luvox Cr?
5Patient Review
1/27/2014 This medication has been a complete game-changer for me. I was struggling with depression and anxiety, and this really helped lessen the intensity and frequency of both.
5Patient Review
7/21/2013 This medication was really effective for me. It got rid of my obsessive thoughts and compulsive behaviors within a week, and also helped with my social anxiety. I would never have believed that something like this could be possible, but it completely changed my life for the better.
5Patient Review
9/25/2013 I've been on this medication for three years and it has completely changed my life. I take it in the morning, which is when I find it to be most effective. The generic from Par Pharma is significantly less effective (in my opinion), so I would only recommend taking Jazz Pharma brand.
5Patient Review
5/11/2012 I experienced great results shortly after taking this medicine, and I continue to feel better than ever.
5Patient Review
10/19/2011 I've been on Luvox for two weeks now, and while it's helped my depression and mood swings, I can't seem to get enough sleep. I'm constantly tired. That being said, I'm otherwise happy with the results of this medication.
5Patient Review
6/13/2022 I'm so grateful that this medication was able to help me. It's truly a lifesaver.
5Patient Review
8/31/2011 Caused me to experience paranoia and fearfulness.
5Patient Review
7/25/20115Patient Review
5/14/2013 I've been on 200mg of Luvox CR for about four years. I suffer from OCD but mostly just obbsesive thoughts. Most days I'm really good and can shut down the thoughts, some days are still tough but the good days far out number the bad days. I really don't suffer from any side effects. The beginnig was the usual, drowsiness,lack of energy but that was gone after a few weeks. This medication has done wonders for me.
5Patient Review
5/16/2013 This medication has been an immense help in managing my OCD.
5Patient Review
7/25/20115Patient Review
8/31/2011 I felt really paranoid and scared while taking this medication.
5Patient Review
5/14/2013 I've been taking 200mg of Luvox CR for four years to help with my OCD. I find that it's effective most days, allowing me to shut down intrusive thoughts. While there can be tough days, they are outnumbered by the good days. Additionally, I didn't experience any long-term side effects from the medication. When I first started taking it there was drowsiness and lack of energy, but those went away after a few weeks.
5Patient Review
10/19/2011 I've been on Luvox CR for two weeks and it's helped my depression and mood swings. The only downside is that I can't seem to stay awake; I'm constantly tired.
5Patient Review
5/16/2013 This medication has been a real game-changer for me and my OCD.
5Patient Review
9/25/2013 I've been on Luvox for three years now to treat my OCD and SAD, and it has quite literally saved my life. I find that taking the medication in the morning is much more effective than at night; however, the generic from Par Pharma is significantly less effective. As a result, I only recommend Jazz Pharma.
5Patient Review
7/21/2013 This medication completely relieved my obsessive thoughts and compulsive behavior within a week, which also dissolved my social anxiety to the point that I can enjoy myself in social situations. The initial few weeks of drowsiness actually proved beneficial as it combatted my anxiety-induced insomnia.
5Patient Review
1/27/2014 This treatment has been a game changer for me. It's helped decrease my panic attacks and severe depression. If you're struggling with something similar, I highly recommend giving this a try.
5Patient Review
6/13/2022 This medication completely changed my life for the better. I'm so thankful that my doctor found something that worked for me.
5Patient Review
5/11/2012 I'm so grateful that this medicine exists! It almost immediately helped me and I've been feeling better than ever for the past few months.
4.7Patient Review
1/21/2014 This worked for me at first, but now it doesn't seem to be as effective.
4.7Patient Review
1/21/2014 This medication was working well for me up until now. I'm not sure what changed, but it's no longer effective.
3.7Patient Review
6/11/2014 I was on Luvox for 10 years and it helped with my OCD thoughts; however, I decided to try natural supplements. This didn't work out too well for me as I couldn't handle the obsessive thoughts at all. So, slowly, I increased my dosage until I was back up to 400mg a day. It worked great again for suppressing the thoughts, but now I'm tired all the time—which is my biggest problem.
3.7Patient Review
6/11/2014 I've been on Luvox CR for a decade now, and it's been great for managing my OCD thoughts. I recently decided to try natural supplements instead, but found that they just didn't work as well for me. I had to go back up to 400mg a day, and am now slowly working my way back down again. The biggest downside for me is the fatigue; it's hard to function when you're constantly exhausted.
3Patient Review
6/7/20113Patient Review
6/7/20112.3Patient Review
1/2/2022 I had a really bad headache after taking this medication.
2.3Patient Review
1/2/2022 I had a really bad headache after taking this medication.
1.3Patient Review
3/25/20111.3Patient Review
3/25/2011Patient Q&A Section about luvox cr
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Luvox CR still available?
"The Luvox CR brand of medication has been discontinued in the United States. However, if the Food and Drug Administration has approved generic versions of this product, there may be generic equivalents available."
Answered by AI
When should I take Luvox CR?
"The dosage is based on your medical condition, response to therapy, age, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Before taking fluvoxamine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
To use Luvox CR, read the Medication Guide provided by your pharmacist before starting to take fluvoxamine. If you have any questions, consult your doctor or pharmacist. This medication is usually taken by mouth once daily at bedtime with or without food, as directed by your doctor. The dosage is based on your medical condition, response to therapy, age, and other medications you may be taking. Make sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Before taking fluvoxamine, tell your doctor or pharmacist if you are allergic to it, or if you have any other allergies"
Answered by AI
Why was Luvox CR discontinued?
"Luvox was removed from the US market in 2002 after it was linked to violent behavior and suicidal thoughts in children and teenagers. The drug received renewed attention after the Columbine Massacre in 1999."
Answered by AI
What is Luvox CR prescribed for?
"LUVOX CR Capsules are indicated for the treatment of obsessive compulsive disorder (OCD) according to the DSM-IV."
Answered by AI