Luvox

Bulimia Nervosa, Obsessive-Compulsive Disorder, Depression
Treatment
1 FDA approval
20 Active Studies for Luvox

What is Luvox

FluvoxamineThe Generic name of this drug
Treatment SummaryFluvoxamine is a type of antidepressant that works by increasing the amount of serotonin in the brain. It is most commonly used to treat obsessive-compulsive disorder, although it is part of the same class of medications as other popular antidepressants. Fluvoxamine has been used since 1983 and has been tested on over 35,000 patients since then. It became available in the US and Japan in the mid-1990s and has been used to treat over 10 million people worldwide since then.
Fluvoxamine Maleateis the brand name
image of different drug pills on a surface
Luvox Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Fluvoxamine Maleate
Fluvoxamine
2000
76

Approved as Treatment by the FDA

Fluvoxamine, otherwise known as Fluvoxamine Maleate, is approved by the FDA for 1 uses including Depression .
Depression
Helps manage Major Depressive Disorder (MDD)

Effectiveness

How Luvox Affects PatientsFluvoxamine is a type of antidepressant called a selective serotonin reuptake inhibitor (SSRI). It is used to treat depression and other mental health disorders like body dysmorphic disorder and anxiety. It works by blocking certain brain cells from taking in serotonin, a natural chemical that controls mood. In lab tests, fluvoxamine was found to have little effect on other brain chemicals like norepinephrine and dopamine. It also does not bind to other types of brain receptors that can cause side effects like confusion or drowsiness. Some studies suggest that taking fluvoxamine long-term might reduce the number of nore
How Luvox works in the bodyFluvoxamine helps treat depression by blocking the brain's serotonin reuptake pump. This means the serotonin stays in the brain longer, allowing it to have a stronger effect on the brain. Fluvoxamine also binds to σ1 receptors, but does not interact with other types of receptors.

When to interrupt dosage

The prescribed dosage of Luvox is contingent upon the recognized condition, including Obsessive-Compulsive Disorder, Depression and Bulimia Nervosa. The extent of dosage is contingent upon the delivery approach (e.g. Tablet or Tablet, film coated - Oral) outlined in the following table.
Condition
Dosage
Administration
Obsessive-Compulsive Disorder
, 25.0 mg, 50.0 mg, 100.0 mg, 150.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
Depression
, 25.0 mg, 50.0 mg, 100.0 mg, 150.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral
Bulimia Nervosa
, 25.0 mg, 50.0 mg, 100.0 mg, 150.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral

Warnings

Luvox Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Luvox.
Common Luvox Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be decreased when combined with Fluvoxamine.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be decreased when combined with Fluvoxamine.
Acyclovir
Major
The metabolism of Acyclovir can be decreased when combined with Fluvoxamine.
Agomelatine
Major
The serum concentration of Agomelatine can be increased when it is combined with Fluvoxamine.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Fluvoxamine.
Luvox Toxicity & Overdose RiskFluvoxamine is an antidepressant that has been linked to increased risk of suicidal thoughts and behavior in children, teens, and young adults up to the age of 24. It is not recommended for use in children except in cases of obsessive-compulsive disorder. Side effects may include lack of appetite, constipation, dry mouth, headache, nausea, feeling anxious, skin rash, trouble sleeping, feeling drowsy, liver damage, manic episodes, increased urination, seizures, excessive sweating, tremors, or Tourette's syndrome.
image of a doctor in a lab doing drug, clinical research

Luvox Novel Uses: Which Conditions Have a Clinical Trial Featuring Luvox?

213 active clinical trials are presently assessing the potential of Luvox to address Obsessive-Compulsive Disorder, Bulimia Nervosa and Depression.
Condition
Clinical Trials
Trial Phases
Bulimia Nervosa
16 Actively Recruiting
Not Applicable, Phase 2, Phase 3, Early Phase 1
Depression
203 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Phase 4, Early Phase 1
Obsessive-Compulsive Disorder
16 Actively Recruiting
Not Applicable, Phase 3, Phase 2

Luvox Reviews: What are patients saying about Luvox?

5Patient Review
2/17/2017
Luvox for Obsessive Compulsive Disorder
This medication has completely changed my life for the better. I highly recommend it to anyone struggling with anxiety or Obsessive Compulsive Disorder.
5Patient Review
6/13/2022
Luvox for Obsessive Compulsive Disorder
I was struggling with obsessive thinking to the point where it was interfering with my life and relationships. This medication has helped me immensely and I'm so grateful for it.
4.7Patient Review
4/23/2017
Luvox for Depression
I've been on Luvox for about nine months now and it's going well.
4.3Patient Review
6/18/2015
Luvox for Obsessive Compulsive Disorder
I've been on Luvox for two years and it's made a world of difference. It took a few months to see the full effect, but it was well worth the wait. I highly recommend this medication to anyone struggling with mental illness.
4.3Patient Review
9/2/2015
Luvox for Obsessive Compulsive Disorder
Luvox has helped me to control my obsessive thoughts, which I've dealt with all my life.
4.3Patient Review
6/6/2021
Luvox for Obsessive Compulsive Disorder
This medication is effective at treating my OCD, but it comes with the side effects of fatigue and low libido.
4Patient Review
4/15/2015
Luvox for Obsessive Compulsive Disorder
It's been effective for my depression, though it took some time to get the dosage right. I've been taking it for several years now with no major issues. The worst side effect is insomnia, which can be a struggle. But overall, this medication has helped me manage my OCD.
4Patient Review
11/3/2016
Luvox for Anxiousness associated with Depression
This medication has been helping me a lot with my anxiety and depression. I'm a survivor of domestic violence, and this has been making it easier for me to cope.
3.7Patient Review
5/18/2019
Luvox for Depression
I've been taking this treatment for twenty years and have generally been very satisfied with it. The downside is that the insomnia can be pretty bad.
3.3Patient Review
11/10/2020
Luvox for Obsessive Compulsive Disorder
Luvox has helped me to some degree, but the side effects have been really tough to deal with. I'm constantly sweaty and my muscles are always stiff. It's not worth it for me.
3.3Patient Review
11/24/2014
Luvox for Depression
I was first prescribed 100 mlg of this medication, but my doctor and I decided to up the dosage to 150 mlg. Since then, I've been having a lot of pain in my muscles, especially in my legs and hips. It's tough to get a good night's sleep when you're dealing with that kind of discomfort. Has anyone else experienced similar problems?
2.3Patient Review
11/30/2015
Luvox for Bipolar Depression
I really didn't enjoy my experience with this medication. I felt like a zombie and had no interest in anything. The side effects were just too much for me to handle, so I switched to Cymbalta instead.
2.3Patient Review
5/1/2016
Luvox for Obsessive Compulsive Disorder
I gained 35 pounds in two months from this medicine, and it made my OCD worse. I had to give up college as a result.
1.3Patient Review
12/21/2014
Luvox for Obsessive Compulsive Disorder
I experienced some very scary side effects after just one dose. My heart rate was pounding, I was sweating, dizzy, and disoriented. I had racing thoughts and felt terrible. I would never take this medicine again.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about luvox

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does Luvox treat anxiety?

"Luvox is available in generic form.

Luvox (fluvoxamine) is a drug used to treat social anxiety disorder and obsessive-compulsive disorder. It is an antidepressant that belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRIs). Luvox is available in generic form."

Answered by AI

How does Luvox make you feel?

"Fluvoxamine may cause people to become agitated, irritable, or display other abnormal behaviors. Children, teenagers, and young adults who take this medication may have suicidal thoughts or tendencies, or may become more depressed."

Answered by AI

Why is Luvox discontinued?

"Luvox was removed from the US market in 2002 because it was believed to be associated with violent behavior and suicidal thinking in children and teenagers. Luvox was removed from the US market following press coverage related to the Columbine Massacre in 1999."

Answered by AI

What is the drug Luvox used for?

"Fluvoxamine is an antidepressant medication that is used to treat obsessive compulsive disorder in adults and children who are at least 8 years old."

Answered by AI

Clinical Trials for Luvox

Have you considered Luvox clinical trials? We made a collection of clinical trials featuring Luvox, we think they might fit your search criteria.
Have you considered Luvox clinical trials? We made a collection of clinical trials featuring Luvox, we think they might fit your search criteria.
Have you considered Luvox clinical trials? We made a collection of clinical trials featuring Luvox, we think they might fit your search criteria.