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What is Khedezla
DesvenlafaxineThe Generic name of this drug
Treatment SummaryDesvenlafaxine is a medication used to treat major depressive disorder. It is a type of antidepressant known as a serotonin-norepinephrine reuptake inhibitor (SNRI). Desvenlafaxine comes in the form of an extended-release tablet and was approved by the FDA in 2008.
Pristiq Extended-Releaseis the brand name
Khedezla Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Pristiq Extended-Release
Desvenlafaxine
2008
87
Approved as Treatment by the FDA
Desvenlafaxine, also known as Pristiq Extended-Release, is approved by the FDA for 1 uses including Depression .Depression
Effectiveness
How Khedezla Affects PatientsDesvenlafaxine is an antidepressant that works by blocking the reuptake of serotonin and norepinephrine. It has no effect on certain receptors, ion channels, and enzymes in the body, meaning it is unlikely to interact with other drugs or cause severe side effects. It also does not need to be adjusted or adjusted to reach a therapeutic dose.
How Khedezla works in the bodyDesvenlafaxine is a drug that helps regulate the amount of serotonin and norepinephrine in the brain. It works by blocking the transporter proteins that reabsorb these molecules, so they stay in the brain longer. Desvenlafaxine has the greatest affinity for serotonin, followed by norepinephrine and then dopamine. It does not interact with monoamine oxidase, or with receptors for other molecules like histamine or adrenaline.
When to interrupt dosage
The proposed dosage of Khedezla relies upon the identified disorder, including Menopause, Hot Flashes and Depression. The quantity fluctuates as per the methodology of administration outlined in the table below.Condition
Dosage
Administration
Depression
, 25.0 mg, 50.0 mg, 100.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Hot Flashes
, 25.0 mg, 50.0 mg, 100.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Hot flashes
, 25.0 mg, 50.0 mg, 100.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Warnings
Khedezla ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Desvenlafaxine may interact with Pulse Frequency
Common Khedezla Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be decreased when combined with Desvenlafaxine.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be decreased when combined with Desvenlafaxine.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Desvenlafaxine.
Alpelisib
Major
The metabolism of Alpelisib can be decreased when combined with Desvenlafaxine.
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Desvenlafaxine.
Khedezla Toxicity & Overdose RiskDesvenlafaxine can be passed through breast milk and so nursing mothers should consider the risks and benefits of continuing the drug or stopping breast feeding.
Khedezla Novel Uses: Which Conditions Have a Clinical Trial Featuring Khedezla?
219 active clinical trials are currently in progress to assess the ability of Khedezla to mitigate Hot Flashes, Depression and associated Menopausal symptoms.Condition
Clinical Trials
Trial Phases
Depression
199 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Phase 4, Early Phase 1
Hot Flashes
14 Actively Recruiting
Phase 3, Not Applicable, Phase 2
Hot flashes
22 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 4, Early Phase 1
Khedezla Reviews: What are patients saying about Khedezla?
5Patient Review
5/15/2015 I've been feeling more irritable, which I think is because I have more energy than before and don't know how to manage it all yet. But I also feel more focused and in control. This treatment started working for me after just four days.
5Patient Review
7/7/2016 This medication has been hugely impactful in a positive way. I've been taking antidepressants for over 20 years, and this is by far the most effective one.
5Patient Review
1/3/20152.3Patient Review
8/26/2015 I experienced no change in my depression after starting this medication, which cost me $360 a month. To me, the decision to stop taking it was a no-brainer.
Patient Q&A Section about khedezla
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Khedezla used for?
"Khedezla is a drug that is used to treat major depressive disorder. It is a serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant."
Answered by AI
What is the difference between Khedezla and Pristiq?
"Desvenlafaxine, marketed under the brand names Pristiq and Khedezla, is a serotonin-norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder (MDD). Khedezla is an extended-release form of desvenlafaxine, and the two drugs differ in the salt form (desvenlafaxine base vs. desvenlafaxine succinate). Generic desvenlafaxine formulations are now available."
Answered by AI
Who manufactures Khedezla?
"We are now shipping KHEDEZLA (desvenlafaxine) Extended-Release Tablets, 50 mg and 100 mg."
Answered by AI
What is the drug desvenlafaxine used for?
"Desvenlafaxine is a medication used to treat depression. It's a type of drug called a serotonin-norepinephrine reuptake inhibitor (SNRI), which are thought to work by increasing the levels of serotonin and norepinephrine in the brain."
Answered by AI