Ivy Block

Itching, Exanthema, Exanthema + 7 more

Treatment

3 FDA approvals

4 Active Studies for Ivy Block

What is Ivy Block

Zinc acetate

The Generic name of this drug

Tecnu Calagel

is the brand name

Ivy Block Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Tecnu Calagel

Zinc acetate

1992

2

Approved as Treatment by the FDA

Zinc acetate, otherwise called Tecnu Calagel, is approved by the FDA for 3 uses which include Pruritus and Skin Irritation .

Pruritus

Skin Irritation

Itching

Effectiveness

How Ivy Block Affects Patients

Zinc is an important mineral that helps with a variety of bodily functions. It's needed for many enzymes to work and helps with immune function, cell division, and wound healing. Zinc also helps people to have a normal sense of taste and smell, and can aid in growth during pregnancy, childhood, and adolescence. It may also have antioxidant properties that could protect people from aging quickly and help heal injuries. Taking zinc supplements orally may help with colds, skin ulcers, and diarrhea, especially in those with low zinc levels. However, taking intranasal zinc is associated with loss of sense of smell, sometimes long-term

How Ivy Block works in the body

Zinc has three primary roles in the body: catalytic, structural, and regulatory. It works in many different ways, from helping proteins and hormones do their job, to acting as an antioxidant, to blocking potassium channels. Low levels of zinc can lead to a weakened immune system, while higher levels can reduce inflammation and protect against infections. It can also help fight acne by inhibiting the bacteria that cause it and reducing the levels of free fatty acids.

When to interrupt dosage

The advised dosage of Ivy Block is contingent upon the diagnosed disorder, including Exanthema, Pain and Exanthema. The measure of dosage fluctuates as per the process of delivery featured in the table below.

Condition

Dosage

Administration

Optic Atrophy, Autosomal Dominant

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

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Exanthema

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

, Lotion - Topical, Topical, Lotion, Spray, Spray - Topical, Cream - Topical, Solution - Topical, Solution, Liquid, Liquid - Topical, Aerosol, spray - Topical, Cream, Capsule, Oral, Capsule - Oral, Soap, Soap - Topical, Gel - Topical, Aerosol, Aerosol, spray, Ointment, Ointment - Topical, Aerosol - Topical, Gel, Auricular (otic), Solution - Auricular (otic), Powder, for suspension - Topical, Powder, for suspension, Kit, Kit - Oral; Topical, Lozenge - Oral, Lozenge, Oral; Topical

Exanthema

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

, Lotion - Topical, Topical, Lotion, Spray, Spray - Topical, Cream - Topical, Solution - Topical, Solution, Liquid, Liquid - Topical, Aerosol, spray - Topical, Cream, Capsule, Oral, Capsule - Oral, Soap, Soap - Topical, Gel - Topical, Aerosol, Aerosol, spray, Ointment, Ointment - Topical, Aerosol - Topical, Gel, Auricular (otic), Solution - Auricular (otic), Powder, for suspension - Topical, Powder, for suspension, Kit, Kit - Oral; Topical, Lozenge - Oral, Lozenge, Oral; Topical

Itching

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

, Lotion - Topical, Topical, Lotion, Spray, Spray - Topical, Cream - Topical, Solution - Topical, Solution, Liquid, Liquid - Topical, Aerosol, spray - Topical, Cream, Capsule, Oral, Capsule - Oral, Soap, Soap - Topical, Gel - Topical, Aerosol, Aerosol, spray, Ointment, Ointment - Topical, Aerosol - Topical, Gel, Auricular (otic), Solution - Auricular (otic), Powder, for suspension - Topical, Powder, for suspension, Kit, Kit - Oral; Topical, Lozenge - Oral, Lozenge, Oral; Topical

Pain

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

, Lotion - Topical, Topical, Lotion, Spray, Spray - Topical, Cream - Topical, Solution - Topical, Solution, Liquid, Liquid - Topical, Aerosol, spray - Topical, Cream, Capsule, Oral, Capsule - Oral, Soap, Soap - Topical, Gel - Topical, Aerosol, Aerosol, spray, Ointment, Ointment - Topical, Aerosol - Topical, Gel, Auricular (otic), Solution - Auricular (otic), Powder, for suspension - Topical, Powder, for suspension, Kit, Kit - Oral; Topical, Lozenge - Oral, Lozenge, Oral; Topical

Exanthema

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

, Lotion - Topical, Topical, Lotion, Spray, Spray - Topical, Cream - Topical, Solution - Topical, Solution, Liquid, Liquid - Topical, Aerosol, spray - Topical, Cream, Capsule, Oral, Capsule - Oral, Soap, Soap - Topical, Gel - Topical, Aerosol, Aerosol, spray, Ointment, Ointment - Topical, Aerosol - Topical, Gel, Auricular (otic), Solution - Auricular (otic), Powder, for suspension - Topical, Powder, for suspension, Kit, Kit - Oral; Topical, Lozenge - Oral, Lozenge, Oral; Topical

Exanthema

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

, Lotion - Topical, Topical, Lotion, Spray, Spray - Topical, Cream - Topical, Solution - Topical, Solution, Liquid, Liquid - Topical, Aerosol, spray - Topical, Cream, Capsule, Oral, Capsule - Oral, Soap, Soap - Topical, Gel - Topical, Aerosol, Aerosol, spray, Ointment, Ointment - Topical, Aerosol - Topical, Gel, Auricular (otic), Solution - Auricular (otic), Powder, for suspension - Topical, Powder, for suspension, Kit, Kit - Oral; Topical, Lozenge - Oral, Lozenge, Oral; Topical

Skin Irritation

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

, Lotion - Topical, Topical, Lotion, Spray, Spray - Topical, Cream - Topical, Solution - Topical, Solution, Liquid, Liquid - Topical, Aerosol, spray - Topical, Cream, Capsule, Oral, Capsule - Oral, Soap, Soap - Topical, Gel - Topical, Aerosol, Aerosol, spray, Ointment, Ointment - Topical, Aerosol - Topical, Gel, Auricular (otic), Solution - Auricular (otic), Powder, for suspension - Topical, Powder, for suspension, Kit, Kit - Oral; Topical, Lozenge - Oral, Lozenge, Oral; Topical

oozing and weeping

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

, Lotion - Topical, Topical, Lotion, Spray, Spray - Topical, Cream - Topical, Solution - Topical, Solution, Liquid, Liquid - Topical, Aerosol, spray - Topical, Cream, Capsule, Oral, Capsule - Oral, Soap, Soap - Topical, Gel - Topical, Aerosol, Aerosol, spray, Ointment, Ointment - Topical, Aerosol - Topical, Gel, Auricular (otic), Solution - Auricular (otic), Powder, for suspension - Topical, Powder, for suspension, Kit, Kit - Oral; Topical, Lozenge - Oral, Lozenge, Oral; Topical

Exanthema

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

, Lotion - Topical, Topical, Lotion, Spray, Spray - Topical, Cream - Topical, Solution - Topical, Solution, Liquid, Liquid - Topical, Aerosol, spray - Topical, Cream, Capsule, Oral, Capsule - Oral, Soap, Soap - Topical, Gel - Topical, Aerosol, Aerosol, spray, Ointment, Ointment - Topical, Aerosol - Topical, Gel, Auricular (otic), Solution - Auricular (otic), Powder, for suspension - Topical, Powder, for suspension, Kit, Kit - Oral; Topical, Lozenge - Oral, Lozenge, Oral; Topical

Warnings

There are 20 known major drug interactions with Ivy Block.

Common Ivy Block Drug Interactions

Drug Name

Risk Level

Description

Deferasirox

Major

Zinc acetate can cause a decrease in the absorption of Deferasirox resulting in a reduced serum concentration and potentially a decrease in efficacy.

Raltegravir

Major

Zinc acetate can cause a decrease in the absorption of Raltegravir resulting in a reduced serum concentration and potentially a decrease in efficacy.

Halofantrine

Minor

Zinc acetate can cause a decrease in the absorption of Halofantrine resulting in a reduced serum concentration and potentially a decrease in efficacy.

Carbamazepine

Moderate

Zinc acetate can cause a decrease in the absorption of Carbamazepine resulting in a reduced serum concentration and potentially a decrease in efficacy.

Ceftibuten

Moderate

Zinc acetate can cause a decrease in the absorption of Ceftibuten resulting in a reduced serum concentration and potentially a decrease in efficacy.

Ivy Block Toxicity & Overdose Risk

The U.S. National Library of Medicine reports that it takes up to 3 grams of zinc per kilogram of body weight to be toxic to humans. This is more than 10 times greater than the toxicity of cadmium and 50 times greater than mercury. Studies have found that rats and mice have an LD50 value for zinc compounds ranging from 186 to 623 mg zinc/kg/day.

Ivy Block Novel Uses: Which Conditions Have a Clinical Trial Featuring Ivy Block?

16 active trials are currently being conducted to assess the potential of Ivy Block to alleviate the symptoms of Poison oak rash, Itch and Pain.

Condition

Clinical Trials

Trial Phases

Exanthema

0 Actively Recruiting

Exanthema

0 Actively Recruiting

Exanthema

0 Actively Recruiting

Exanthema

0 Actively Recruiting

Skin Irritation

0 Actively Recruiting

Pain

0 Actively Recruiting

oozing and weeping

0 Actively Recruiting

Exanthema

0 Actively Recruiting

Itching

3 Actively Recruiting

Phase 3, Not Applicable

Optic Atrophy, Autosomal Dominant

1 Actively Recruiting

Not Applicable

Patient Q&A Section about ivy block

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How do u treat poison ivy?

"Apply an over the counter cortisone cream or ointment to the affected area for the first few days. Apply calamine lotion or cream containing menthol to the area. Take an oral antihistamine such as diphenhydramine to help with the itch and to help you sleep better."

Answered by AI

What is Ivy Block?

"Ivy Block can be used as a shield to protect the skin from poison ivy, poison oak, and poison sumac. The best way to avoid getting these conditions is to avoid contact with these plants."

Answered by AI

Does poison ivy Block work?

"Clinical trials have demonstrated that POISON OAK & IVY BLOCK lotion is safe, effective and able to provide relief from poison ivy, poison oak and poison sumac. The POISON OAK & IVY BLOCK lotion formula acts to block the source of the itching and rash associated with poison ivy, oak and sumac."

Answered by AI

What is a poison ivy blocker?

"Bentoquatam lotion is used to prevent spread of poison oak, poison ivy, and poison sumac rashes. It works by forming a barrier on the skin that protects it from the plant oils that may cause a rash."

Answered by AI

Clinical Trials for Ivy Block

Image of Johns Hopkins Bayview Medical Center in Baltimore, United States.

VR-Enhanced PMR for Post-Burn Symptoms

18+
All Sexes
Baltimore, MD

The goal of this clinical trial is to learn whether progressive muscle relaxation (PMR), delivered either alone or enhanced with virtual reality (VR), can help treat chronic symptom, such as pain, itch, anxiety, sleep disturbances, and fatigue, in adult burn survivors. The main questions it aims to answer are: * Does VR-enhanced PMR (VR-PMR) reduce chronic pain, anxiety, itch, sleep disturbances, and fatigue more effectively than standard PMR? * Is VR-PMR a feasible and acceptable self-administered home-based intervention for burn survivors? Researchers will compare two self-administered intervention conditions, VR-enhanced PMR and standard PMR, using a randomized to sequence crossover design to see if VR technology enhances the therapeutic effects of PMR on chronic symptom management in burn survivors. Participants will: * Complete home-based sessions of VR-enhanced PMR * Complete home-based sessions of standard PMR * Report symptoms such as pain, itch, anxiety, sleep disturbances, and fatigue throughout the study * Use VR equipment provided for the intervention period (during the VR-PMR arm)

Recruiting
Has No Placebo

Johns Hopkins Bayview Medical Center

Sheera Lerman Zohar, PhD