Hytrin

Enlarged Prostate, Hypertensive disease, Ureteral Calculi
Treatment
2 FDA approvals
20 Active Studies for Hytrin

What is Hytrin

TerazosinThe Generic name of this drug
Treatment SummaryTerazosin is a medication used to treat high blood pressure and an enlarged prostate. It works by blocking the action of adrenaline on certain receptors in the body, which relaxes the muscles in the blood vessels and prostate.
Hytrinis the brand name
image of different drug pills on a surface
Hytrin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Hytrin
Terazosin
1987
173

Approved as Treatment by the FDA

Terazosin, otherwise known as Hytrin, is approved by the FDA for 2 uses including Hypertensive disease and Enlarged Prostate .
Hypertensive disease
Helps manage High Blood Pressure (Hypertension)
Enlarged Prostate

Effectiveness

How Hytrin Affects PatientsTerazosin is a type of medication that blocks a certain type of hormone (alpha-1) that helps regulate blood pressure.
How Hytrin works in the bodyTerazosin targets alpha-1-adrenoceptors, relaxing the smooth muscles in blood vessels and the prostate. This helps lower blood pressure and improves urinary flow. It also stimulates the caspase cascade, leading to apoptosis of prostate cells. This helps to reduce the size of the prostate and ease pressure on the urethra. Finally, it inhibits mitogenesis, preventing the growth of cancerous cells.

When to interrupt dosage

The measure of Hytrin is subject to the diagnosed condition, including Ureteral Calculus, Hypertensive disease and Enlarged Prostate. The quantity fluctuates as per the administration mode (e.g. Capsule, liquid filled or Capsule - Oral) indicated in the table below.
Condition
Dosage
Administration
Enlarged Prostate
10.0 mg, , 1.0 mg, 2.0 mg, 5.0 mg
, Oral, Capsule, Capsule - Oral, Tablet - Oral, Tablet, Kit; Tablet, Kit; Tablet - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral
Hypertensive disease
10.0 mg, , 1.0 mg, 2.0 mg, 5.0 mg
, Oral, Capsule, Capsule - Oral, Tablet - Oral, Tablet, Kit; Tablet, Kit; Tablet - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral
Ureteral Calculi
10.0 mg, , 1.0 mg, 2.0 mg, 5.0 mg
, Oral, Capsule, Capsule - Oral, Tablet - Oral, Tablet, Kit; Tablet, Kit; Tablet - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral

Warnings

Hytrin Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Terazosin may interact with Pulse Frequency
There are 20 known major drug interactions with Hytrin.
Common Hytrin Drug Interactions
Drug Name
Risk Level
Description
Acepromazine
Major
Terazosin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Acepromazine.
Alfuzosin
Major
Terazosin may increase the hypotensive activities of Alfuzosin.
Amifostine
Major
Terazosin may increase the hypotensive activities of Amifostine.
Aripiprazole
Major
Terazosin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole.
Aripiprazole lauroxil
Major
Terazosin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole lauroxil.
Hytrin Toxicity & Overdose RiskAn overdose of terazosin may lead to low blood pressure; this can be treated by having the patient lay down, or through the use of fluids or drugs to increase blood pressure. It is important to monitor kidney function, as terazosin is highly protein-bound and dialysis will not help remove the drug from the body. The lowest toxic dose of terazosin in mice has been found to be 5500mg/kg.
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Hytrin Novel Uses: Which Conditions Have a Clinical Trial Featuring Hytrin?

39 active studies are currently being conducted to assess the effectiveness of Hytrin for the treatment of Enlarged Prostate, Ureteral Calculus and Hypertensive Disease.
Condition
Clinical Trials
Trial Phases
Hypertensive disease
23 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Enlarged Prostate
21 Actively Recruiting
Not Applicable, Phase 4, Phase 2
Ureteral Calculi
0 Actively Recruiting

Hytrin Reviews: What are patients saying about Hytrin?

5Patient Review
11/30/2010
Hytrin for Enlarged Prostate
I've been taking 1mg of Hytrin for several months now at bedtime and it has worked well for me. I get a very restful sleep, dream more often, and feel like my mood and energy levels have increased. However, I have begun experiencing pain and tingling in my hands (which may or may not be caused by the Hytrin), as well as increased hair loss (again, possibly unrelated).
5Patient Review
2/27/2014
Hytrin for Enlarged Prostate
I've been taking this medication for over five years now to treat my BPH, and it's been great. I haven't experienced any negative side effects, and it's even helped lower my blood pressure into the normal range. If I miss a dose, though, I have real difficulty urinating.
5Patient Review
10/27/2013
Hytrin for Enlarged Prostate
I've found this treatment helpful, but I still experience some pains in my lower back after sitting or standing for a while. If anyone has any suggestions, I'm all ears.
5Patient Review
3/5/2013
Hytrin for Enlarged Prostate
I carefully monitor my blood pressure and dosage. I take about 4mg at night and 4mg in the morning. This is good medicine for three reasons: it helps me sleep at night, aids with urination, and lowers blood pressure a little bit.
4.7Patient Review
11/18/2011
Hytrin for Enlarged Prostate
I've only just started taking this, but so far I'm pleased.
View All Reviews
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Patient Q&A Section about hytrin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the common side effects of terazosin?

"Symptoms of the flu include feeling weak or tired, having a stuffy or runny nose, back pain, nausea, and weight gain. Flu symptoms can also include decreased sexual ability and blurred vision."

Answered by AI

Can terazosin give you an erection?

"If you experience a painful erection that lasts for hours, go to the nearest emergency room. Priapism is a condition that, if left untreated, can lead to impotence."

Answered by AI

Is Hytrin the same as Flomax?

"Hytrin (Terazosin) and Flomax (tamsulosin) are equally effective as similar medications, but with fewer and less severe side effects. They help make urinating easier, and are available in generic form. Hytrin is also available in a combination form with another medication to treat severe symptoms of enlarged prostate."

Answered by AI

What is Hytrin used for?

"This medication is used to lower blood pressure. By relaxing blood vessels, it allows blood to flow more easily and prevents strokes, heart attacks, and kidney problems."

Answered by AI

Clinical Trials for Hytrin

Have you considered Hytrin clinical trials? We made a collection of clinical trials featuring Hytrin, we think they might fit your search criteria.
Have you considered Hytrin clinical trials? We made a collection of clinical trials featuring Hytrin, we think they might fit your search criteria.
Have you considered Hytrin clinical trials? We made a collection of clinical trials featuring Hytrin, we think they might fit your search criteria.
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