Glucagen

Gastrointestinal tract structure, Hypoglycemia, Type 2 Diabetes + 1 more

Treatment

3 FDA approvals

20 Active Studies for Glucagen

Treatment for

Gastrointestinal tract structure

What is Glucagen

GlucagonThe Generic name of this drug

Treatment SummaryGlucagon is a hormone made up of 29 amino acids that is used to treat severe low blood sugar and help create a still image of the gastrointestinal tract during X-rays. It helps raise blood sugar levels by activating receptors in the liver, which then triggers the release of glucose. Glucagon was approved by the FDA in 1960.

Glucagonis the brand name

Glucagen Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Glucagon

1999

Approved as Treatment by the FDA

Glucagon, otherwise called Glucagon, is approved by the FDA for 3 uses including Hypoglycemia and severe Hypoglycemia .

Hypoglycemia

severe Hypoglycemia

Gastrointestinal tract structure

Effectiveness

How Glucagen Affects PatientsGlucagon is used as a diagnostic tool to temporarily slow down the digestive system and treat very low blood sugar. It works by activating receptors in the liver, which causes it to release sugar. Glucagon is short-acting, but can cause high blood sugar levels in people with diabetes.

How Glucagen works in the bodyGlucagon binds to its receptor, which triggers a chain of events inside the cell. This includes increased production of energy-producing molecules, as well as the breakdown of glycogen, which helps to provide energy to the body. Glucagon also relaxes the muscles in the stomach and intestines.

When to interrupt dosage

The measure of Glucagen is contingent upon the determined illness, including Gastrointestinal tract structure, Type 2 Diabetes and Type 2 Diabetes. The dosage is dependent on the strategy of conveyance (e.g. Intramuscular; Intravenous; Subcutaneous or Injection, powder, for solution - Intramuscular; Intravenous; Subcutaneous) as indicated in the accompanying table.

Condition

Dosage

Administration

Gastrointestinal tract structure

, 1.0 mg/mL, 1.0 mg, 3.0 mg, 5.0 mg/mL, 10.0 mg/mL, 0.5 mg

, Kit, Intramuscular; Intravenous; Subcutaneous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous; Subcutaneous, Kit; Powder, for solution, Kit; Powder, for solution - Intramuscular; Intravenous; Subcutaneous, Powder, for solution - Intramuscular; Intravenous; Subcutaneous, Powder, for solution, Intramuscular, Kit; Powder, for solution - Intramuscular, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Kit - Intramuscular; Intravenous; Subcutaneous, Powder - Nasal, Nasal, Powder, Injection, solution, Subcutaneous, Injection, solution - Subcutaneous, Kit - Intramuscular; Intravenous

Hypoglycemia

, 1.0 mg/mL, 1.0 mg, 3.0 mg, 5.0 mg/mL, 10.0 mg/mL, 0.5 mg

Type 2 Diabetes

, 1.0 mg/mL, 1.0 mg, 3.0 mg, 5.0 mg/mL, 10.0 mg/mL, 0.5 mg

Type 2 Diabetes

, 1.0 mg/mL, 1.0 mg, 3.0 mg, 5.0 mg/mL, 10.0 mg/mL, 0.5 mg

Warnings

Glucagen Contraindications

Condition

Risk Level

Notes

Glucagonoma

Do Not Combine

Insulinoma

Do Not Combine

Pheochromocytoma

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Glucagon may interact with Pulse Frequency

There are 20 known major drug interactions with Glucagen.

Common Glucagen Drug Interactions

Drug Name

Risk Level

Description

(R)-warfarin

Minor

The therapeutic efficacy of (R)-warfarin can be increased when used in combination with Glucagon.

(S)-Warfarin

Minor

The therapeutic efficacy of (S)-Warfarin can be increased when used in combination with Glucagon.

4-hydroxycoumarin

Minor

The therapeutic efficacy of 4-hydroxycoumarin can be increased when used in combination with Glucagon.

Acenocoumarol

Minor

The therapeutic efficacy of Acenocoumarol can be increased when used in combination with Glucagon.

Clorindione

Minor

The therapeutic efficacy of Clorindione can be increased when used in combination with Glucagon.

Glucagen Toxicity & Overdose RiskSigns of an overdose on glucagon may include nausea, vomiting, slowed digestion, high blood pressure, a fast heart rate, and low potassium levels. Phentolamine may be given to reduce the blood pressure, while treatment for other symptoms is largely symptomatic. The lowest toxic dose of glucagon in rats and mice has been found to be 38.6mg/kg and 300mg/kg respectively.

Glucagen Novel Uses: Which Conditions Have a Clinical Trial Featuring Glucagen?

248 active studies are being conducted to assess Glucagen's potential for alleviating Type 2 Diabetes, Hypoglycemia and other Type 2 Diabetes-related conditions.

Condition

Clinical Trials

Trial Phases

Type 2 Diabetes

90 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1

Type 2 Diabetes

177 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1

Hypoglycemia

0 Actively Recruiting

Gastrointestinal tract structure

0 Actively Recruiting

Glucagen Reviews: What are patients saying about Glucagen?

4Patient Review

12/19/2011

Glucagen for Low Blood Sugar

Patient Q&A Section about glucagen

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How do you administer GlucaGen?

"The recommended dosage of GlucaGen® is 1 mg (1 mL) injected subcutaneously or intramuscularly into the upper arm, thigh, or buttocks, or intravenously. If there is no response after 15 minutes, an additional 1 mg dose (1 mL) may be administered using a new kit while waiting for emergency assistance."

Answered by AI

What is the difference between GlucaGen and glucagon?

"Glucagon is a medication used to treat severe hypoglycemia (very low blood sugar) in diabetics. It works by increasing blood glucose levels."

Answered by AI

What is the effect of a GlucaGen?

"Glucagon is a hormone that helps regulating blood glucose levels produced by the pancreas. Glucagon prevents blood sugar levels from dropping too low, while insulin hormone decreases blood sugar levels."

Answered by AI

When do you give GlucaGen?

"If a person with diabetes is unconscious or unable to eat or drink, they need sugar right away. Glucagon raises the blood sugar quickly and can be administered by someone close to the person with diabetes in an emergency."

Answered by AI

Clinical Trials for Glucagen

Have you considered Glucagen clinical trials? We made a collection of clinical trials featuring Glucagen, we think they might fit your search criteria.

Have you considered Glucagen clinical trials? We made a collection of clinical trials featuring Glucagen, we think they might fit your search criteria.