Gentak

Inflammation, Ecthyma, Eczema + 36 more
Treatment
11 FDA approvals
20 Active Studies for Gentak

What is Gentak

GentamicinThe Generic name of this drug
Treatment SummaryGentamicin is an antibiotic that was discovered in 1963. It is widely prescribed due to its ability to fight both gram-positive and gram-negative bacteria, especially Pseudomonas aeruginosa. Gentamicin works well when combined with other antibiotics, which can reduce the amount of drug required and minimize side effects. However, gentamicin can cause serious side effects such as kidney and hearing damage, so it should be used with caution.
Gentamicinis the brand name
image of different drug pills on a surface
Gentak Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Gentamicin
Gentamicin
1982
125

Approved as Treatment by the FDA

Gentamicin, also called Gentamicin, is approved by the FDA for 11 uses including Communicable Diseases and severe Infection Pseudomonas aeruginosa .
Communicable Diseases
Used to treat Susceptible infections in combination with Betamethasone
severe Infection Pseudomonas aeruginosa
Used to treat severe Infection Pseudomonas aeruginosa in combination with Carbenicillin
severe Endocarditis enterococcal
Used to treat severe Endocarditis enterococcal in combination with Benzylpenicillin
Inflammation
Used to treat Inflammation in combination with Betamethasone
Bacterial Infections
Skin Infections
Used to treat Skin Infections in combination with Betamethasone
Inflammation
Used to treat Inflammation in combination with Betamethasone
Communicable Diseases
Used to treat severe Infection Pseudomonas aeruginosa in combination with Carbenicillin
Communicable Diseases
Used to treat Skin Infections in combination with Betamethasone
Endocarditis
Used to treat severe Endocarditis enterococcal in combination with Benzylpenicillin
Urinary Tract Infection (UTI)

Effectiveness

How Gentak works in the bodyAminoglycosides work in two ways to kill bacteria. First, they bind to the cell membranes of bacteria, which weakens the membrane and allows the medicine to enter. Once inside, the medicine binds to the ribosome, which is responsible for making proteins. This causes the proteins to be made incorrectly, which weakens the cell membrane further and prevents the cell from reproducing. Finally, the medicine accumulates in the cell, causing it to die. Aminoglycosides are not effective against anaerobic bacteria since they require oxygen for transport.

When to interrupt dosage

The suggested portion of Gentak is reliant upon the diagnosed situation, for instance Blepharitis, Corneal infection and Dermatitis infected. The amount of dosage additionally fluctuates as per the technique of delivery (e.g. Intravenous or Liquid - Ophthalmic; Topical) indicated in the table beneath.
Condition
Dosage
Administration
Conjunctivitis, Bacterial
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Keratoconjunctivitis
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
ocular bacterial infections
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Blepharoconjunctivitis
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Pustular acne
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Skin Diseases
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Impetigo contagious
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Endocarditis
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Bacterial Infections
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Urinary Tract Infections
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Conjunctivitis
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Communicable Diseases
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Inflammation
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Eczema
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Pyoderma Gangrenosum
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Corneal infection
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Dacryocystitis
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Meibomianitis
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Sycosis barbae
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)
Sycosis
0.001 mg/mg, , 10.0 mg/mL, 40.0 mg/mL, 1.2 mg/mL, 1.4 mg/mL, 1.6 mg/mL, 0.8 mg/mL, 0.9 mg/mL, 1.0 mg/mL, 0.003 mg/mg, 3.0 mg/mL, 0.3 %, 0.1 %, 4.5 mg, 6.0 mg/mL, 8.0 mg/mL, 0.6 mg/mL, 0.4 mg/mL, 12.0 mg/mL, 5.0 mg/mL, 0.005 mg/mg
, Topical, Cream, Ointment, Ointment - Topical, Cream - Topical, Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intravenous, Ophthalmic, Solution, Ointment - Ophthalmic, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Injection, solution, concentrate - Intramuscular; Intravenous, Solution - Intravenous, Liquid, Solution / drops - Auricular (otic), Solution - Auricular (otic); Ophthalmic, Ointment - Ophthalmic; Topical, Liquid - Ophthalmic; Topical, Ophthalmic; Topical, Solution / drops - Ophthalmic; Topical, Implant, Implant - Parenteral, Suspension / drops - Ophthalmic, Solution - Intramuscular; Intravenous, Suspension / drops, Parenteral, Auricular (otic); Ophthalmic, Liquid - Ophthalmic, Liquid - Auricular (otic); Ophthalmic, Liquid - Intramuscular; Intravenous, Auricular (otic), Solution - Auricular (otic)

Warnings

Gentak has two contraindications, thus it should not be taken concurrently with the conditions listed in the following table.Gentak Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Gentamicin may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Gentamicin may interact with Pulse Frequency
There are 20 known major drug interactions with Gentak.
Common Gentak Drug Interactions
Drug Name
Risk Level
Description
Agalsidase beta
Major
The therapeutic efficacy of Agalsidase beta can be decreased when used in combination with Gentamicin.
Neomycin
Major
The risk or severity of nephrotoxicity can be increased when Gentamicin is combined with Neomycin.
Tenofovir
Major
Gentamicin may increase the nephrotoxic activities of Tenofovir.
Tenofovir alafenamide
Major
Gentamicin may increase the nephrotoxic activities of Tenofovir alafenamide.
Tenofovir disoproxil
Major
Gentamicin may increase the nephrotoxic activities of Tenofovir disoproxil.
Gentak Toxicity & Overdose RiskGentamicin has been linked to kidney and ear damage, with symptoms including increased creatinine and urea levels in the blood, balance issues, nausea, tinnitus, and hearing loss. Long-term use of gentamicin increases the risk of these toxicities and may lead to permanent ear damage. To reduce the risk of toxicity, patients should be closely monitored and the medication stopped immediately in cases of toxicity or overdose. Hemodialysis may also be used to lower gentamicin serum concentrations.
image of a doctor in a lab doing drug, clinical research

Gentak Novel Uses: Which Conditions Have a Clinical Trial Featuring Gentak?

219 active clinical trials are currently underway to investigate the potential of Gentak to reduce Inflammation, Ocular Inflammation and Allergic Conjunctivitis (AC).
Condition
Clinical Trials
Trial Phases
Inflammation
58 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1, Phase 2, Phase 3, Phase 4
Bacterial Infections
0 Actively Recruiting
Communicable Diseases
0 Actively Recruiting
Keratitis
0 Actively Recruiting
Sycosis barbae
0 Actively Recruiting
Blepharoconjunctivitis
0 Actively Recruiting
Keratoconjunctivitis
0 Actively Recruiting
Pustular Psoriasis (PP)
0 Actively Recruiting
Ecthyma
0 Actively Recruiting
Impetigo contagious
0 Actively Recruiting
ocular bacterial infections
0 Actively Recruiting
Dacryocystitis
0 Actively Recruiting
Staphylococcal Infections
0 Actively Recruiting
Urinary Tract Infections
0 Actively Recruiting
Bacterial Peritonitis
0 Actively Recruiting
Pyoderma Gangrenosum
2 Actively Recruiting
Phase 2, Phase 3
Pustular acne
0 Actively Recruiting
Endocarditis
0 Actively Recruiting
Allergic Conjunctivitis (AC)
1 Actively Recruiting
Phase 2
Sycosis
0 Actively Recruiting

Gentak Reviews: What are patients saying about Gentak?

3.3Patient Review
9/28/2011
Gentak for Bacterial Infection of the Eyelid
I unfortunately had an allergic reaction to the medication.
1.7Patient Review
9/16/2011
Gentak for Inflammation of Eyelid Edges and the Lining of the Eye
My eye was very itchy on the edges, so I saw a doctor. They said I had an infection and prescribed this medication. Three times a day for three days. It's now been three days and my eyes are no better; in fact, they might even be worse.
1.7Patient Review
5/11/2012
Gentak for Pink Eye from Bacterial Infection
I found this easy enough to use, but unfortunately it didn't work for me.
1.3Patient Review
6/28/2011
Gentak for Bacterial Infection of the Eyelid
Gentak was prescribed by my doctor to treat a stye. However, after just two days of use, both of my eyes had swollen shut. Additionally, the eyelids had developed horrible blisters. The medicine in the eye that didn't have the stye caused eye blisters and ulcers. Consequently, I would not recommend this medication to anyone.
1.3Patient Review
1/3/2015
Gentak for Bacterial Infection of the Eyelid
I was prescribed this ointment for conjunctivitis, but it is very difficult to apply. After four days of the five-day treatment, I stopped using it because of the pain, burning, and itchiness. I'll have to go back to the doctor.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about gentak

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Gentak used for pink eye?

"Gentamicin is an antibiotic that is used to treat bacterial infections of the eye and eyelid. This medication can be given after eye surgery or injury to help prevent bacterial infections from happening."

Answered by AI

What is Gentak ointment used for?

"This medication is used to treat bacterial infections of the eye, such as blepharitis and conjunctivitis, and the skin around the eyes, such as eyelids. It is also used to prevent infection after eye injury or surgery. It belongs to a class of drugs known as aminoglycoside antibiotics."

Answered by AI

Is Gentak still made?

"Akorn has stopped making Gentak."

Answered by AI

Is Gentak a prescription?

"Gentak is a medicine used to treat the symptoms of Conjunctivitis (pink eye) and to prevent infections after surgery. Gentak may be used alone or with other medications."

Answered by AI

Clinical Trials for Gentak

Image of UConn Health in Farmington, United States.

Cognitive Remediation for Memory and Thinking Difficulties

18+
All Sexes
Farmington, CT
The goal of this clinical trial is to determine if a neuroscience-based computerized cognitive remediation ("brain training") program can treat neurocognitive dysfunction (i.e., memory or thinking difficulties) that emerges in some older adults following a viral infection. The main questions it aims to answer are: * Does computerized cognitive remediation improve cognitive performance and day-to-day functioning in older adults with postviral neurocognitive dysfunction? * Will treatment effects be maintained over time, leading to better long term cognitive outcomes? * Does the treatment lead to reductions in blood-based markers of inflammation as a potential mechanism of cognitive symptom improvement? * Can the treatment be optimized and refined based on feedback from participants to improve user (patient) experience? Researchers will compare the computerized cognitive remediation program to an active computer-based control condition (alternative computer activities) to see if the computerized cognitive remediation program works to treat postviral neurocognitive dysfunction. Participation takes approximately 43-48 hours over 7 months, with most activities (40-46 hours) completed within the first 7-8 weeks, including: * Initial intake visit: Eligibility confirmation (\~2-3 hours) * Computer activities: About 5 hours per week for \~6 weeks (total \~30 hours) completed on a computer tablet provided by the study and loaned to participants for use during the treatment phase * Weekly remote check-in meetings: \~30 minutes each during treatment * Blood draws: Two sessions (before and after treatment), \~20-30 minutes each * Three research visits: Pre-treatment, post-treatment, and 6-month follow-up (\~2-3 hours each, including assessments of cognitive, emotional, and daily functioning)
Waitlist Available
Has No Placebo
UConn HealthCutter Lindbergh, Ph.D.
Have you considered Gentak clinical trials? We made a collection of clinical trials featuring Gentak, we think they might fit your search criteria.Go to Trials
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Freeze-dried Grape Powder for Healthy Aging

50 - 75
All Sexes
Storrs, CT
The purpose of this study is to investigate the effects of consuming grape powder on immune profiles in healthy middle- and older-aged individuals. Specifically, the investigators are interested in evaluating the potential effects of grapes in influencing markers of immune function, inflammation, and metabolism that are known to change with aging. Grapes contain several nutrients and antioxidant polyphenols such as resveratrol, quercetin, vitamin K and fiber, which are known to promote heart and immune health. However, the effects of grapes on altering immune profiles within the context of aging is not well understood. Therefore, this study will explore how daily grape consumption impacts certain markers of immunity in healthy middle- and older-aged adults. The main study procedures include consumption of a freeze-dried grape powder and control powder (which tastes the same but has none of the grape compounds that are being studied) mixed with water as a beverage on a daily basis for 4 weeks each. The investigators will additionally ask that participants avoid eating grapes and certain other antioxidant/grape-related foods and beverages throughout the 13-week study. Participants will additionally be asked to complete surveys about their diet, physical activity, and medical history, as well as provide blood samples and body weight measures throughout the course of the study. Participation in the study is expected to last about 6.25 hours over the course of 13 weeks and will include 7 visits.
Recruiting
Paid Trial
Department of Nutritional Sciences
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Orticumab for Heart Attack

18+
All Sexes
Los Angeles, CA
The goal of this clinical trial is to determine the clinical effect of orticumab treatment on inflammation in study participants with prior myocardial infarction who have elevated coronary inflammation based on CCTA. The main question it aims to answer is: Clinical effects of orticumab treatment on inflammation of the coronary artery parameters measured with CCTA Researchers will compare the effects with placebo group after 6 months of treatment Participants will Keep the planned study visit appointments Provide complete information about medical and medical history Speak to the study doctor before changing any of non-study treatments, including starting new medications, receiving any vaccinations, or setting out to join any other clinical studies
Phase 2
Recruiting
Abcentra Investigational Site (+6 Sites)Abcentra
Image of School of Public Health in Bloomington, United States.

High Salt Intake for High Blood Pressure

60 - 85
All Sexes
Bloomington, IN
Most Americans consume excess dietary salt based on the recommendations set by the American Heart Association and Dietary Guidelines for Americans. High dietary salt impairs blood pressure control by affecting systemic blood vessels and the kidneys. These changes contribute to excess salt consumption being associated with increased risk for chronic kidney disease and cardiovascular disease, the leading cause of death in America. Salt is particularly deleterious in older adults who are more likely to exhibit salt-sensitive hypertension. However, salt consumption remains high in the United States. Thus, there is a critical need for strategies to counteract the effects of high dietary salt as consumption is likely not going to decrease. One promising option is ketones, metabolites that are produced in the liver during prolonged exercise and very low-calorie diets. While exercise and low-calorie diets are beneficial, not many people engage in these activities. Limited evidence indicates that ketone supplements improve cardiovascular health in humans. Additionally, published rodent data indicates that ketone supplements prevent high salt-induced increases in blood pressure, blood vessel dysfunction, and kidney injury. Our human pilot data also indicates that high dietary salt reduces intrinsic ketone production, but it is unclear whether ketone supplementation confers humans' protection against high salt similar to rodents. Therefore, the investigators seek to conduct a short-term high-dietary salt study to determine whether ketone supplementation prevents high dietary salt from eliciting increased blood pressure, blood vessel dysfunction, and kidney injury/impaired blood flow. The investigators will also measure inflammatory markers in blood samples and isolate immune cells that control inflammation. Lastly, the investigators will also measure blood ketone concentration and other circulating metabolites that may be altered by high salt, which could facilitate novel therapeutic targets to combat high salt.
Recruiting
Has No Placebo
School of Public Health
Image of Tesla MedBed at Tampa-FL in Tampa, United States.

Biophoton Therapy for Stem Cell Proliferation

18 - 70
All Sexes
Tampa, FL
Study Objective The purpose of this clinical study is to evaluate if biophoton therapy, delivered by Tesla BioHealing® Biophoton Generators (Biophotonizer), can increase self-grown stem cells naturally. Study Design This is a randomized, double-blinded, placebo-controlled intervention clinical study to assess the effectiveness of biophoton therapy in impacting stem cells. Approximately 46 volunteers who want to increase self-grown stem cells will participate in the study. Study Randomization The biostatistician will prepare a randomization schedule including a serial of subject numbers. A subject number will be randomly assigned to each study participant, which will assign them to either the control group or the treatment group. Other than the Informed Consent Form (ICF), all study information will be recorded by using the subject number. The Principal Investigator, study physicians, study nurse, data-entry specialists, and biostatisticians, as well as the participants, will be blinded about who received which product during the first two weeks of study participation.
Recruiting
Online Trial
Tesla MedBed at Tampa-FL (+1 Sites)James Z Liu, MD, PhD
Have you considered Gentak clinical trials? We made a collection of clinical trials featuring Gentak, we think they might fit your search criteria.Go to Trials
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Physical Activity for Delayed Onset Muscle Soreness

18 - 35
All Sexes
Toronto, Canada
After completing novel activity or exercise we may experience exercise-induced muscle damage (EIMD), resulting in a period of reduced muscle function and delayed onset muscle soreness (DOMS). DOMS is characterized by muscle pain and tenderness that typically resolves within a week. While the precise cause of DOMS is unknown, there is growing evidence implicating damage to the connective tissue that surrounds our muscle fibers and is related to a small amount of inflammation. This inflammation is a normal part of our body's ability to recovery from injuries and may be visualized through the use of ultrasound technology. A variety of recovery techniques have been proposed that may help with the recovery of DOMS such as massage and electrical muscle stimulation, but these are not always accessible. Therefore, we are interested in investigating whether the number of daily steps can affect how you experience DOMS.
Waitlist Available
Has No Placebo
Goldring Center for High Performance Sport
Image of UCSF in San Francisco, United States.

Moisturizers for Aging

65+
All Sexes
San Francisco, CA
This is a randomized, investigator-blinded, self-controlled pilot study of the physiologic response to topical moisturizers among older adults with dry skin. The overarching hypothesis is that skin barrier decline is an important source of chronic inflammation, and that skin barrier restoration with moisturizers can reduce serum biomarkers of inflammation. The primary objective is to determine the feasibility for a larger trial, and the secondary objectives are to determine the extent to which measures of serum inflammation, skin barrier function, and the skin microbiome change in response to moisturizers. Participants will be asked to apply one of two topical moisturizers that are widely available over the counter in the US (Vaseline® 100% pure petroleum jelly or CeraVe® moisturizing cream) once daily for 4 weeks to the front of the torso, buttocks, arms, and legs. Subjects will act as their own control (i.e. they will be asked to apply the study moisturizer they are randomized to for one intervention period (4 weeks) and not to apply topical moisturizers for the other 4- week intervention period). Participants will be randomized in a 1:1:1:1 ratio to one of 4 treatment groups: i. no intervention then CeraVe; ii. CeraVe then no intervention; iii. no intervention then Vaseline; iv. Vaseline then no intervention. At each visit (baseline, week 4, and week 8), participants will undergo skin barrier testing, skin microbiome sampling, and phlebotomy to measure serum inflammatory markers.
Phase 4
Recruiting
UCSFKatrina Abuabara, MD
Have you considered Gentak clinical trials? We made a collection of clinical trials featuring Gentak, we think they might fit your search criteria.Go to Trials
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