Gastrografin

Retrograde cystourethrography, Arteriography, discography + 10 more

Treatment

12 FDA approvals

1 Active Study for Gastrografin

Treatment for

Retrograde cystourethrography

What is Gastrografin

Diatrizoate

The Generic name of this drug

Treatment Summary

Diatrizoate is a type of x-ray contrast medium used to make organs or tissues appear clearer on an x-ray image. It is used for gastrointestinal studies, angiography (study of blood vessels) and urography (study of the urinary tract). It is available in two forms, diatrizoate meglumine and diatrizoate sodium.

Renografin-60

is the brand name

image of different drug pills on a surface

Gastrografin Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Renografin-60

Diatrizoate

1956

Approved as Treatment by the FDA

Diatrizoate, also known as Renografin-60, is approved by the FDA for 12 uses which include computerized tomography and peripheral arteriography .

computerized tomography

peripheral arteriography

angiogram

splenoportography

Gastrointestinal and abdominal imaging procedures

Retrograde cystourethrography

Arteriography

excretory urography

Cholangiography

Arteriography

discography

selective coronary arteriography

Effectiveness

How Gastrografin Affects Patients

Diatrizoate is a type of drug that helps doctors diagnose medical conditions. It is made of iodine, which blocks x-rays, and when given to a patient it builds up in certain areas of the body. The x-ray film will show these areas as white, which helps doctors see if there are any special conditions in those areas.

How Gastrografin works in the body

Diatrizoate is a type of X-ray contrast agent that contains iodine. The iodine makes the X-ray contrast more visible, so doctors can better see what's happening inside the body. It's a clear, colorless water solution that's safe to use almost anywhere in the body. It's often injected into a vein, but it can also be used in other areas like the spine, arteries, and abdomen.

When to interrupt dosage

The recommended dosage of Gastrografin is contingent upon the ascertained disorder, like Arteriography, angiogram and Gastrointestinal and abdominal imaging procedures. The dosage quantity varies as per the technique of administration recorded in the table below.

Condition

Dosage

Administration

selective coronary arteriography

, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg

, Intravenous, Injection, solution, Injection, solution - Intravenous, Oral; Rectal, Intravesical, Injection, solution - Intravesical, Liquid, Injection, solution - Intrauterine, Intrauterine, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Liquid - Intramuscular; Intravenous, Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular, Powder, for solution

Arteriography

hysterosalpingogram

excretory urography

splenoportography

peripheral arteriography

Cholangiography

Retrograde cystourethrography

Arteriography

discography

angiogram

Gastrointestinal and abdominal imaging procedures

computerized tomography

Warnings

Gastrografin has eight contraindications and should not be employed in combination with the circumstances mentioned in the table below.

Gastrografin Contraindications

Condition

Risk Level

Notes

Carotid Arteries

Do Not Combine

Anuria

Do Not Combine

dehydrated azotemic patients

Do Not Combine

Sphenoid Sinusitis

Do Not Combine

direct injection into spinal arteries

Do Not Combine

Myelography

Do Not Combine

Structure of vertebral artery

Do Not Combine

use for examination of dorsal cysts

Do Not Combine

There are 20 known major drug interactions with Gastrografin.

Common Gastrografin Drug Interactions

Drug Name

Risk Level

Description

Abacavir

Minor

Diatrizoate may decrease the excretion rate of Abacavir which could result in a higher serum level.

Acetaminophen

Minor

Diatrizoate may decrease the excretion rate of Acetaminophen which could result in a higher serum level.

Aclidinium

Minor

Diatrizoate may decrease the excretion rate of Aclidinium which could result in a higher serum level.

Acrivastine

Minor

Diatrizoate may decrease the excretion rate of Acrivastine which could result in a higher serum level.

Albutrepenonacog alfa

Minor

Diatrizoate may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.

Gastrografin Toxicity & Overdose Risk

Diatrizoate, a type of high-osmolality radiocontrast agent, can be toxic to kidney cells. The toxicity can lead to cell death, energy failure, changes in calcium levels, and disorganization of the cell structure. This toxicity is believed to be caused by oxidative stress.

image of a doctor in a lab doing drug, clinical research

Gastrografin Novel Uses: Which Conditions Have a Clinical Trial Featuring Gastrografin?

A single active clinical trial is currently being conducted to appraise the efficacy of Gastrografin in providing hysterosalpingogram, Arteriography and excretory urography for treatment of certain disorders.

Condition

Clinical Trials

Trial Phases

selective coronary arteriography

0 Actively Recruiting

Arteriography

0 Actively Recruiting

splenoportography

0 Actively Recruiting

Arteriography

0 Actively Recruiting

hysterosalpingogram

0 Actively Recruiting

Cholangiography

0 Actively Recruiting

computerized tomography

1 Actively Recruiting

Phase 2

Retrograde cystourethrography

0 Actively Recruiting

discography

0 Actively Recruiting

peripheral arteriography

0 Actively Recruiting

angiogram

0 Actively Recruiting

excretory urography

0 Actively Recruiting

Gastrointestinal and abdominal imaging procedures

0 Actively Recruiting

Gastrografin Reviews: What are patients saying about Gastrografin?

Patient Review

1/2/2017

Gastrografin for Process of Making X-Rays of Stomach or Intestines

Even though this drink tastes like Nuclear Waste, it really helped the doctors locate my abscesses.

4.3

Patient Review

11/22/2013

Gastrografin for Process of Making X-Rays of Stomach or Intestines

Even though the taste was really bad, I took Gastrografin as directed. Afterwards, I had lots of diarrhea that lasted for nine days. Is this normal?

Patient Review

2/23/2017

Gastrografin for Process of Making X-Rays of Stomach or Intestines

I had to drink a litre of this stuff, which tasted like aniseed at first but quickly became unpalatable. I experienced some bloating and wind after drinking it, followed by stomach pain and diarrhea four hours later.

Patient Review

6/17/2021

Gastrografin for Process of Making X-Rays of Stomach or Intestines

I took the first half at 7 am the day before the C T scan took the second half at 7 pm it started to work at 10 pm, My C T scan was 11am the next morning i got to the hospital and the bowel was still working they done the CT scan and when they had finished the scan the bowel started to work again what a mess, i got home and the bowel stop working at 4 p m. The hospital should tell to take Gastrografin two day's before there would not be a problem

Patient Review

9/30/2014

Gastrografin for X-Rays Done for Diagnostic Purposes

This treatment successfully removed a small bowel obstruction that I was experiencing. However, the severe diarrhea that followed for the next 24 hours was quite unpleasant.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about gastrografin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does Gastrografin make you poop?

"Gastrografin is a mild laxative. It will remove most stool, but it can also help us distinguish stool from polyps. The test may fail, and we may need to repeat it."

Answered by AI

What are side effects of Gastrografin?

"If you experience any of the following symptoms after taking medication, you may be experiencing an allergy: nausea, vomiting, diarrhea, hives and redness, low blood oxygen, shortness of breath, fast heart rate, and severe allergic reaction (anaphylaxis)."

Answered by AI

Is Gastrografin oral contrast?

"Gastrografin is a substance used to help radiologists see the gastrointestinal tract more clearly. It can be given orally or as an enema, and is usually only used when other substances (such as barium sulfate) can't be used."

Answered by AI

What is Gastrografin for small bowel obstruction?

"Gastrografin is a contrast medium that is commonly used to examine the gastrointestinal tract. The available evidence suggests that it can help predict and manage adhesional small bowel obstruction."

Answered by AI