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What is Gabitril
TiagabineThe Generic name of this drug
Treatment SummaryTiagabine is a medication used to prevent and treat seizures. It can also be used to treat panic disorder. The way it works is not entirely understood, but it is thought to act as a selective inhibitor of the neurotransmitter GABA.
Gabitrilis the brand name
Gabitril Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Gabitril
Tiagabine
1997
33
Approved as Treatment by the FDA
Tiagabine, commonly known as Gabitril, is approved by the FDA for 1 uses including Seizures .Seizures
Effectiveness
How Gabitril Affects PatientsTiagabine is used to treat epilepsy. Its effects come from its ability to increase the activity of gamma aminobutyric acid (GABA), a chemical in the brain that helps keep activity from getting too high. Tiagabine attaches to sites on cells and prevents the uptake of GABA, so more of it can be available for cells to use.
How Gabitril works in the bodyTiagabine works by blocking the reabsorption of the neurotransmitter GABA, which helps to regulate nerve activity.
When to interrupt dosage
The proposed measure of Gabitril is contingent upon the diagnosed circumstances. The measure of dosage differs, depending on the delivery system (e.g. Tablet or Tablet - Oral) detailed in the table beneath.Condition
Dosage
Administration
Seizures
, 12.0 mg, 4.0 mg, 2.0 mg, 16.0 mg, 20.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule - Oral, Capsule
Warnings
There are 20 known major drug interactions with Gabitril.Common Gabitril Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Tiagabine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Ethanol
Major
Tiagabine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Oliceridine
Major
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Tiagabine is combined with Oliceridine.
Thalidomide
Major
Tiagabine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Daridorexant
Minor
The risk or severity of CNS depression can be increased when Tiagabine is combined with Daridorexant.
Gabitril Toxicity & Overdose RiskTaking too much tiagabine can lead to seizures, unconsciousness, disruption of muscle coordination, confusion, drowsiness, slurred speech, restlessness, lethargy, twitching, stupor, trembling, disorientation, vomiting, hostility, and temporary immobility. Some patients, including children, may also experience difficulty breathing.
Gabitril Novel Uses: Which Conditions Have a Clinical Trial Featuring Gabitril?
There are two ongoing studies to ascertain the effectiveness of Gabitril in the management of Seizures.Condition
Clinical Trials
Trial Phases
Seizures
2 Actively Recruiting
Phase 3
Gabitril Reviews: What are patients saying about Gabitril?
3.3Patient Review
11/14/2007 This drug has helped me to control my partial seizures, though I still have the occasional breakthrough seizure.
3.3Patient Review
2/26/2009 I was prescribed this for petit mal and grand mal seizures. I was taking 16mg, three times daily. It helped somewhat, but caused me to have seizures on a continuous cycle for two years. With that and loss of seizure control my doctor chose to take me off the drug. Now that I'm off the medication, my cycle has gone back to once monthly.
1.3Patient Review
8/22/2008 Gabitril made my seizures worse after being seizure free for over a decade. I'm lucky that my new neurologist was an epilepsy specialist and caught this side effect.
Patient Q&A Section about gabitril
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Gabitril and gabapentin the same thing?
"Tiagabine and gabapentin are not the same medication, even though they are both antiepileptics that involve GABA, a chemical in the brain that calms nerves."
Answered by AI
What are the side effects of Gabitril?
"You may experience dizziness, drowsiness, stomach pain, diarrhea, nervousness, tiredness, or shaking. If you notice any of these effects lasting or getting worse, tell your doctor or pharmacist."
Answered by AI
What is Gabitril used to treat?
"GABITRIL is a prescription medicine used to treat partial seizures in adults and children age 12 and older, in conjunction with other medications."
Answered by AI