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What is Fycompa
PerampanelThe Generic name of this drug
Treatment SummaryPerampanel (brand name Fycompa™) is a medication used to treat seizures in patients over 12 years old. It works by blocking the action of the chemical glutamate, which can cause seizures. There is an important warning that Fycompa™ can cause serious or life-threatening behavioral and psychiatric reactions.
Fycompais the brand name
Fycompa Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Fycompa
Perampanel
2012
9
Effectiveness
How Fycompa Affects PatientsPerampanel helps to reduce activity in the brain and can cause slower thinking and movement.
How Fycompa works in the bodyPerampanel reduces the activity of over-excited neurons by blocking the AMPA receptor. This helps to control seizures.
When to interrupt dosage
The suggested dosage of Fycompa is contingent upon the diagnosed condition. The amount of dosage is reliant upon the administration methodology outlined in the table beneath.Condition
Dosage
Administration
Secondarily Generalized Seizures
, 6.0 mg, 12.0 mg, 4.0 mg, 8.0 mg, 10.0 mg, 2.0 mg, 0.5 mg/mL
Kit, , Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Suspension, Suspension - Oral
Epilepsies
, 6.0 mg, 12.0 mg, 4.0 mg, 8.0 mg, 10.0 mg, 2.0 mg, 0.5 mg/mL
Kit, , Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Suspension, Suspension - Oral
Epilepsy
, 6.0 mg, 12.0 mg, 4.0 mg, 8.0 mg, 10.0 mg, 2.0 mg, 0.5 mg/mL
Kit, , Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Suspension, Suspension - Oral
Seizures
, 6.0 mg, 12.0 mg, 4.0 mg, 8.0 mg, 10.0 mg, 2.0 mg, 0.5 mg/mL
Kit, , Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Suspension, Suspension - Oral
Warnings
Fycompa ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Common Fycompa Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Perampanel.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Perampanel.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Perampanel.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Perampanel.
Astemizole
Major
The metabolism of Astemizole can be increased when combined with Perampanel.
Fycompa Toxicity & Overdose RiskTaking perampanel may lead to serious or even life-threatening behavioral and psychiatric reactions, such as aggression, hostility, irritability, anger, and thoughts of homicide. The FDA requires this warning to be included on the label.
Fycompa Novel Uses: Which Conditions Have a Clinical Trial Featuring Fycompa?
There are two ongoing clinical trials assessing the potential of Fycompa to provide therapeutic benefit for Seizures.Condition
Clinical Trials
Trial Phases
Secondarily Generalized Seizures
0 Actively Recruiting
Epilepsies
0 Actively Recruiting
Seizures
2 Actively Recruiting
Phase 3
Epilepsy
0 Actively Recruiting
Fycompa Reviews: What are patients saying about Fycompa?
5Patient Review
3/23/2015 I haven't had a seizure in over 18 months since I started taking this medication, which is amazing. The occasional bout of dizziness is worth it to me to be seizure-free.
5Patient Review
10/13/2022 This medication has been absolutely life-changing. I had a lot of problems before starting to take it, but since then I've been feeling better than ever.
5Patient Review
6/16/2022 I used to have seizures every morning when I woke up, but since I've been taking this medication, I haven't had a single one. It's truly a lifesaver.
4.3Patient Review
7/15/2014 On the plus side, this medication helps me sleep for much longer periods of time. However, I do feel more "out of it" than usual; though, since I only take it at night, it's not really a problem. It has proven very effective in reducing my seizure frequency.
4Patient Review
12/15/2019 I find that, when I have a seizure, I can usually control it and fight it off.
2.7Patient Review
2/7/2015 I found that as my blood level rose, I became clumsy and dizzy. If I took it too close to bedtime, I would have trouble speaking and become euphoric. My insurance wasn't going to pay for it, so I weaned off it too quickly and after 7 days of stopping it, I had unbearable anguish that I knew was drug related. I had three sample packs; all of this happened after taking it for only 5 weeks. It has been almost a month since i took my last pill, and I still feel strange even now. This is a very scary drug.
2.7Patient Review
4/19/2018 I started by taking 8mg tablets once a day before bed, but now my stomach is really sensitive to everything. I have nausea every morning, and it's just a never-ending cycle. I hate this medicine because it's the only one that has worked for me, but the side effects are really miserable.
2.7Patient Review
11/9/2015 My 14 year old son started taking this medication and, since then, his grades have tanked, he's become unrecognizable personality-wise, and struggles to stay awake in school. The neurologist says these symptoms will eventually go away; I'm keeping my fingers crossed.
Patient Q&A Section about fycompa
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Fycompa used for?
"FYCOMPA is a prescription medicine that is used to treat partial-onset seizures with or without secondarily generalized seizures in people with epilepsy who are aged 4 and older. It is also used to treat primary generalized tonic-clonic seizures in people with epilepsy who are aged 12 and older."
Answered by AI
Can Fycompa get you high?
"Some people who took Fycompa in clinical studies reported feeling "high". This was more common in people who took a 12 milligram (mg) dose per day compared to those who took lower doses (4 mg or 8 mg per day)."
Answered by AI
What type of medication is Fycompa?
"Fycompa is a medication used to treat seizures in adults and children. It is used to treat partial onset seizures that may or may not develop into general seizures in people with epilepsy who are at least 4 years old."
Answered by AI
Is Fycompa a narcotic?
"FYCOMPA is a medication that has the potential to be abused or lead to drug dependence, and is therefore classified as a controlled substance (CIII). Keep your FYCOMPA in a safe place where it will not be stolen, and never give it to anyone else, as it could cause them harm."
Answered by AI