Fycompa

Seizures, Epilepsy, Epilepsy + 1 more

Treatment

5 Active Studies for Fycompa

Treatment for

Seizures

What is Fycompa

Perampanel

The Generic name of this drug

Treatment Summary

Perampanel (brand name Fycompa™) is a medication used to treat seizures in patients over 12 years old. It works by blocking the action of the chemical glutamate, which can cause seizures. There is an important warning that Fycompa™ can cause serious or life-threatening behavioral and psychiatric reactions.

Fycompa

is the brand name

image of different drug pills on a surface

Fycompa Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Fycompa

Perampanel

2012

Effectiveness

How Fycompa Affects Patients

Perampanel helps to reduce activity in the brain and can cause slower thinking and movement.

How Fycompa works in the body

Perampanel reduces the activity of over-excited neurons by blocking the AMPA receptor. This helps to control seizures.

When to interrupt dosage

The suggested dosage of Fycompa is contingent upon the diagnosed condition. The amount of dosage is reliant upon the administration methodology outlined in the table beneath.

Condition

Dosage

Administration

Epilepsy

, 6.0 mg, 12.0 mg, 4.0 mg, 8.0 mg, 10.0 mg, 2.0 mg, 0.5 mg/mL

Kit, , Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Suspension, Suspension - Oral

Epilepsy

, 6.0 mg, 12.0 mg, 4.0 mg, 8.0 mg, 10.0 mg, 2.0 mg, 0.5 mg/mL

Kit, , Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Suspension, Suspension - Oral

Seizures

, 6.0 mg, 12.0 mg, 4.0 mg, 8.0 mg, 10.0 mg, 2.0 mg, 0.5 mg/mL

Kit, , Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Suspension, Suspension - Oral

Seizures

, 6.0 mg, 12.0 mg, 4.0 mg, 8.0 mg, 10.0 mg, 2.0 mg, 0.5 mg/mL

Kit, , Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Suspension, Suspension - Oral

Warnings

Fycompa Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

There are 20 known major drug interactions with Fycompa.

Common Fycompa Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Perampanel.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be increased when combined with Perampanel.

Alectinib

Major

The metabolism of Alectinib can be increased when combined with Perampanel.

Aminophylline

Major

The metabolism of Aminophylline can be increased when combined with Perampanel.

Astemizole

Major

The metabolism of Astemizole can be increased when combined with Perampanel.

Fycompa Toxicity & Overdose Risk

Taking perampanel may lead to serious or even life-threatening behavioral and psychiatric reactions, such as aggression, hostility, irritability, anger, and thoughts of homicide. The FDA requires this warning to be included on the label.

image of a doctor in a lab doing drug, clinical research

Fycompa Novel Uses: Which Conditions Have a Clinical Trial Featuring Fycompa?

There are two ongoing clinical trials assessing the potential of Fycompa to provide therapeutic benefit for Seizures.

Condition

Clinical Trials

Trial Phases

Seizures

0 Actively Recruiting

Seizures

5 Actively Recruiting

Phase 3, Phase 2, Phase 1

Epilepsy

0 Actively Recruiting

Epilepsy

0 Actively Recruiting

Fycompa Reviews: What are patients saying about Fycompa?

Patient Review

3/23/2015

Fycompa for Additional Medication to Treat Partial Seizures

I haven't had a seizure in over 18 months since I started taking this medication, which is amazing. The occasional bout of dizziness is worth it to me to be seizure-free.

Patient Review

10/13/2022

Fycompa for Additional Medication for Tonic-Clonic Epilepsy

This medication has been absolutely life-changing. I had a lot of problems before starting to take it, but since then I've been feeling better than ever.

Patient Review

6/16/2022

Fycompa for Additional Medication to Treat Partial Seizures

I used to have seizures every morning when I woke up, but since I've been taking this medication, I haven't had a single one. It's truly a lifesaver.

4.3

Patient Review

7/15/2014

Fycompa for Additional Medication to Treat Partial Seizures

On the plus side, this medication helps me sleep for much longer periods of time. However, I do feel more "out of it" than usual; though, since I only take it at night, it's not really a problem. It has proven very effective in reducing my seizure frequency.

Patient Review

12/15/2019

Fycompa for Additional Medication for Tonic-Clonic Epilepsy

I find that, when I have a seizure, I can usually control it and fight it off.

2.7

Patient Review

2/7/2015

Fycompa for Additional Medication to Treat Partial Seizures

I found that as my blood level rose, I became clumsy and dizzy. If I took it too close to bedtime, I would have trouble speaking and become euphoric. My insurance wasn't going to pay for it, so I weaned off it too quickly and after 7 days of stopping it, I had unbearable anguish that I knew was drug related. I had three sample packs; all of this happened after taking it for only 5 weeks. It has been almost a month since i took my last pill, and I still feel strange even now. This is a very scary drug.

2.7

Patient Review

4/19/2018

Fycompa for Additional Medication for Tonic-Clonic Epilepsy

I started by taking 8mg tablets once a day before bed, but now my stomach is really sensitive to everything. I have nausea every morning, and it's just a never-ending cycle. I hate this medicine because it's the only one that has worked for me, but the side effects are really miserable.

2.7

Patient Review

11/9/2015

Fycompa for Additional Medication for Tonic-Clonic Epilepsy

My 14 year old son started taking this medication and, since then, his grades have tanked, he's become unrecognizable personality-wise, and struggles to stay awake in school. The neurologist says these symptoms will eventually go away; I'm keeping my fingers crossed.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about fycompa

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Fycompa used for?

"FYCOMPA is a prescription medicine that is used to treat partial-onset seizures with or without secondarily generalized seizures in people with epilepsy who are aged 4 and older. It is also used to treat primary generalized tonic-clonic seizures in people with epilepsy who are aged 12 and older."

Answered by AI

Can Fycompa get you high?

"Some people who took Fycompa in clinical studies reported feeling "high". This was more common in people who took a 12 milligram (mg) dose per day compared to those who took lower doses (4 mg or 8 mg per day)."

Answered by AI

What type of medication is Fycompa?

"Fycompa is a medication used to treat seizures in adults and children. It is used to treat partial onset seizures that may or may not develop into general seizures in people with epilepsy who are at least 4 years old."

Answered by AI

Is Fycompa a narcotic?

"FYCOMPA is a medication that has the potential to be abused or lead to drug dependence, and is therefore classified as a controlled substance (CIII). Keep your FYCOMPA in a safe place where it will not be stolen, and never give it to anyone else, as it could cause them harm."

Answered by AI