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What is Emtriva
EmtricitabineThe Generic name of this drug
Treatment SummaryEmtricitabine is a drug used to treat HIV in adults and to prevent HIV infection in adolescents and adults at high risk of infection. It works by preventing the virus from converting its RNA into DNA, thus stopping it from replicating. This medication was approved by the FDA in 2003 and is a type of medication known as a nucleoside reverse transcriptase inhibitor (NRTI).
Emtrivais the brand name
Emtriva Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Emtriva
Emtricitabine
2003
131
Approved as Treatment by the FDA
Emtricitabine, also called Emtriva, is approved by the FDA for 2 uses including HIV and adults and pediatric patients weighing at least 17 kg .HIV
Helps manage Human Immunodeficiency Virus Type 1 (HIV-1) Infection
adults and pediatric patients weighing at least 17 kg
Effectiveness
How Emtriva Affects PatientsEmtricitabine is a drug used to treat HIV-1. It works by blocking the virus from making more copies of itself, and is taken once a day. Patients should be aware that this drug may cause lactic acidosis and an enlarged liver with fat deposits.
How Emtriva works in the bodyEmtricitabine works to stop HIV from replicating. It does this by blocking a protein called HIV-1 reverse transcriptase, which is needed for the virus to make copies of itself. Emtricitabine competes with a building block of DNA, and when it wins the competition, it prevents the virus from making more copies. This reduces the viral load, or the amount of virus in the body.
When to interrupt dosage
The suggested dose of Emtriva hinges on the identified condition, like HIV (Human Immunodeficiency Virus), Human Immunodeficiency Virus Type 1 (HIV-1) and HIV Transmission. The extent of dosage is contingent upon the delivery technique detailed in the following table.Condition
Dosage
Administration
HIV Transmission
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
HIV test negative
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
HIV
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
Anti-Retroviral Agents
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
weight more than 35 kg
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
weight at least 14 kg
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
HIV
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
HIV
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
HIV Infections
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
weight at least 35 kg
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
Antiretroviral Therapy
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
treatment failure
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
adults and pediatric patients weighing at least 17 kg
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
Sexual Behaviour
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
not requiring CYP3A inhibitors
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
Warnings
Emtriva has two contraindications, so it should not be administered while having any of the conditions outlined in the subsequent table.Emtriva ContraindicationsCondition
Risk Level
Notes
HIV
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Emtricitabine may interact with Pulse Frequency
Common Emtriva Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The excretion of Abemaciclib can be decreased when combined with Emtricitabine.
Procainamide
Major
The excretion of Procainamide can be decreased when combined with Emtricitabine.
Topotecan
Major
The excretion of Topotecan can be decreased when combined with Emtricitabine.
Cefradine
Minor
The excretion of Cefradine can be decreased when combined with Emtricitabine.
Estrone sulfate
Minor
The excretion of Estrone sulfate can be decreased when combined with Emtricitabine.
Emtriva Toxicity & Overdose RiskThe toxic dose of emtricitabine is unknown. Signs of poisoning can include liver damage and accumulation of fat in the liver, as well as lactic acidosis. Treatment for an overdose may involve providing symptomatic and supportive care, as well as hemodialysis.
Emtriva Novel Uses: Which Conditions Have a Clinical Trial Featuring Emtriva?
172 active trials are presently being conducted to analyze the potency of Emtriva in treating HIV, HIV (Human Immunodeficiency Virus) and adults and pediatric patients with a weight of at least 17 kg.Condition
Clinical Trials
Trial Phases
treatment failure
0 Actively Recruiting
HIV Transmission
0 Actively Recruiting
HIV
0 Actively Recruiting
Anti-Retroviral Agents
0 Actively Recruiting
HIV Infections
0 Actively Recruiting
HIV test negative
0 Actively Recruiting
adults and pediatric patients weighing at least 17 kg
0 Actively Recruiting
Antiretroviral Therapy
2 Actively Recruiting
Phase 3, Phase 1
HIV
42 Actively Recruiting
Phase 2, Phase 3, Phase 1, Phase 4, Not Applicable, Early Phase 1
HIV
146 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 3, Phase 4, Early Phase 1
not requiring CYP3A inhibitors
0 Actively Recruiting
weight more than 35 kg
0 Actively Recruiting
weight at least 35 kg
0 Actively Recruiting
weight at least 14 kg
0 Actively Recruiting
Sexual Behaviour
17 Actively Recruiting
Phase 2, Not Applicable, Phase 4
Emtriva Reviews: What are patients saying about Emtriva?
3.7Patient Review
9/22/2010 I didn't really feel any difference after taking this medication.
Patient Q&A Section about emtriva
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What class of drug is rilpivirine?
"Rilpivirine is a medication that inhibits the activity of reverse transcriptase, an enzyme that is essential for the replication of the HIV virus. By inhibiting this enzyme, rilpivirine decreases the amount of HIV in the blood."
Answered by AI
What is EMTRIVA used to treat?
"Emtricitabine blocks the activity of an enzyme called reverse transcriptase. This enzyme is needed for the virus to multiply. Emtricitabine reduces the amount of HIV in the blood and helps to boost the CD4 cell count.
Emtricitabine is an antiretroviral medication used to treat human immunodeficiency virus (HIV) infection. Emtricitabine works by blocking the activity of an enzyme called reverse transcriptase. This enzyme is needed for the virus to multiply. By reducing the amount of HIV in the blood, Emtricitabine helps to boost the CD4 cell count."
Answered by AI
What is the generic of EMTRIVA?
"Emtrivac is the brand name of a nucleoside analog with activity against human immunodeficiency virus type 1 (HIV-1) reverse transcriptase."
Answered by AI
Can EMTRIVA prevent infection?
"Two drugs used to prevent HIV, Emtricitabine and Tenofovir, work by reverse transcriptase inhibitors. The combination of the two drugs has been authorized in the United States to help prevent HIV-1 infection in adults who are at high risk, in addition to other preventive measures."
Answered by AI