Emtricitabine

Antiretroviral Therapy, HIV test negative, HIV Infections + 12 more

Treatment

2 FDA approvals

20 Active Studies for Emtricitabine

Treatment for

Antiretroviral Therapy

What is Emtricitabine

EmtricitabineThe Generic name of this drug

Treatment SummaryEmtricitabine is a medication used to treat HIV infection in adults or to prevent HIV infection in high-risk adolescents and adults. It works by interfering with the replication of the virus, preventing it from spreading. Emtricitabine was approved by the FDA in 2003 and is a type of medication known as a nucleoside reverse transcriptase inhibitor (NRTI).

Emtrivais the brand name

image of different drug pills on a surface

Emtricitabine Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Emtriva

Emtricitabine

2003

131

Approved as Treatment by the FDA

Emtricitabine, also called Emtriva, is approved by the FDA for 2 uses including HIV and adults and pediatric patients weighing at least 17 kg .

HIV

Helps manage Human Immunodeficiency Virus Type 1 (HIV-1) Infection

adults and pediatric patients weighing at least 17 kg

Effectiveness

How Emtricitabine Affects PatientsEmtricitabine is a drug used to treat HIV-1. It works by replacing the natural substance that HIV-1 needs to create new DNA and stopping its growth. It is taken once a day, so it is effective for a long time. It is important for patients to be aware of the risks of lactic acidosis and liver damage.

How Emtricitabine works in the bodyEmtricitabine stops HIV from replicating. It does this by competing with the virus's DNA for a spot on the host's DNA, making it difficult for the virus to spread. It also blocks the virus's reverse transcriptase, which is needed for the virus to turn its RNA into DNA. By preventing this process, the virus is unable to create additional copies of itself and its spread is limited.

When to interrupt dosage

The recommended dose of Emtricitabine is contingent upon the designated condition, including HIV (Human Immunodeficiency Virus), Human Immunodeficiency Virus Type 1 (HIV-1) and HIV Transmission. The dosage additionally fluctuates as per the technique of delivery stated in the table below.

Condition

Dosage

Administration

HIV test negative

200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg

, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral

HIV

200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg

, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral

HIV Transmission

200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg

, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral

HIV

200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg

, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral

weight at least 14 kg

200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg

, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral

weight more than 35 kg

200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg

, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral

HIV

200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg

, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral

HIV Infections

200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg

, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral

weight at least 35 kg

200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg

, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral

Antiretroviral Therapy

200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg

, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral

treatment failure

200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg

, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral

Anti-Retroviral Agents

200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg

, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral

adults and pediatric patients weighing at least 17 kg

200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg

, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral

Sexual Behaviour

200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg

, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral

not requiring CYP3A inhibitors

200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg

, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral

Warnings

Emtricitabine Contraindications

Condition

Risk Level

Notes

HIV

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Emtricitabine may interact with Pulse Frequency

There are 20 known major drug interactions with Emtricitabine.

Common Emtricitabine Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The excretion of Abemaciclib can be decreased when combined with Emtricitabine.

Procainamide

Major

The excretion of Procainamide can be decreased when combined with Emtricitabine.

Topotecan

Major

The excretion of Topotecan can be decreased when combined with Emtricitabine.

Cefradine

Minor

The excretion of Cefradine can be decreased when combined with Emtricitabine.

Estrone sulfate

Minor

The excretion of Estrone sulfate can be decreased when combined with Emtricitabine.

Emtricitabine Toxicity & Overdose RiskThe amount of emtricitabine needed to cause toxic effects is not known. Symptoms of emtricitabine toxicity include liver damage and fatty buildup, as well as a buildup of lactic acid in the body. If someone overdoses on emtricitabine, they should be treated with supportive care and hemodialysis.

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Emtricitabine Novel Uses: Which Conditions Have a Clinical Trial Featuring Emtricitabine?

172 active trials are being conducted to evaluate the potential of Emtricitabine to treat HIV, HIV (Human Immunodeficiency Virus) Infections, in adults and pediatric patients with a minimum weight of 17 kg.

Condition

Clinical Trials

Trial Phases

treatment failure

0 Actively Recruiting

HIV Transmission

0 Actively Recruiting

HIV

0 Actively Recruiting

Anti-Retroviral Agents

0 Actively Recruiting

HIV Infections

0 Actively Recruiting

HIV test negative

0 Actively Recruiting

adults and pediatric patients weighing at least 17 kg

0 Actively Recruiting

Antiretroviral Therapy

2 Actively Recruiting

Phase 3, Phase 1

HIV

41 Actively Recruiting

Phase 2, Phase 3, Phase 1, Phase 4, Not Applicable, Early Phase 1

HIV

147 Actively Recruiting

Phase 2, Not Applicable, Phase 1, Phase 3, Phase 4, Early Phase 1

not requiring CYP3A inhibitors

0 Actively Recruiting

weight more than 35 kg

0 Actively Recruiting

weight at least 35 kg

0 Actively Recruiting

weight at least 14 kg

0 Actively Recruiting

Sexual Behaviour

17 Actively Recruiting

Phase 2, Not Applicable, Phase 4

Emtricitabine Reviews: What are patients saying about Emtricitabine?

4Patient Review

8/23/2010

Emtricitabine for HIV

1Patient Review

7/8/2017

Emtricitabine for Prevention of HIV Infection after Exposure

I experienced a lot of negative side effects from this drug, including but not limited to: salivating, nausea, difficulty thinking and sleeping, tightness in my chest. I was taking it in combination with raltegravir for prophylaxis.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about emtricitabine

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can emtricitabine be used as Pep?

"Nov 13, 2015 - The World Health Organization recommends that people who have been potentially exposed to HIV take the drug Truvada as soon as possible. This is known as "PEP" therapy, and is indicated for nonoccupational exposure, such as patients who were sexually assaulted or who injection drugs."

Answered by AI

What is the difference between Truvada and emtricitabine?

"Truvada is the brand name for a combination of two drugs, emtricitabine and tenofovir disoproxil fumarate. This combination was FDA-approved in 2004 for HIV treatment. However, compared to Descovy, Truvada has been shown to have more adverse effects on kidney function and bone density."

Answered by AI

What is the drug emtricitabine used for?

"Emtricitabine is used with other medications to treat human immunodeficiency virus (HIV) infection. Emtricitabine belongs to a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). These medications work by decreasing the amount of HIV in the blood."

Answered by AI

What is another name for emtricitabine?

"Emtricitabine/tenofovir, a fixed-dose combination antiretroviral medication, is used to treat and prevent HIV/AIDS. The drug is sold under the brand name Truvada and Descovy."

Answered by AI

Clinical Trials for Emtricitabine

Image of Site 4601, University of California, UC San Diego CRS- Mother-Child-Adolescent HIV Program in La Jolla, United States.

Cabotegravir & Rilpivirine for HIV

"This trial aims to study the safety and effectiveness of long-acting injectable medications in pregnant women with HIV and their infants. The study will focus on how the medications are processed in the body and their

Waitlist Available

Site 4601, University of California, UC San Diego CRS- Mother-Child-Adolescent HIV Program (+3 Sites)

Image of Alabama CRS in Birmingham, United States.

16055 NFL Delta Gly4 Env Protein Trimer +2 More for HIV/AIDS

This trial aims to test two different vaccines in adults without HIV to see if they are safe and well-tolerated. The study will also explore whether the vaccines can help in the development of B-cell

Alabama CRS (+5 Sites)

Image of University of Virginia Fontaine Research Park in Charlottesville, United States.

Aim 1 Survey for Alcohol Use Disorder

Charlottesville, VA

This trial aims to collect information to create a digital app that Native American women can use on any device to prevent alcohol-affected pregnancies. Desired output format: "This trial aims to create a

Waitlist Available

University of Virginia Fontaine Research Park

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Nowhi Isdza bit Nadagoldi: Telling Our Daughters Our Story (TODOS) for Substance Abuse

This trial aims to assess the effectiveness of a culturally grounded program called "Nowhi Isdza bit Nadagoldi: Telling Our Daughters Our Story" on American Indian (AI) female

Waitlist Available

White Mountain Apache Center for Indigenous HealthMary Barlow, PhD

Have you considered Emtricitabine clinical trials? We made a collection of clinical trials featuring Emtricitabine, we think they might fit your search criteria.

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Image of Alabama CRS (Site ID: 31788) in Birmingham, United States.

CD4BS CH505M5 Pr-NP1 for HIV/AIDS

This trial is testing two HIV vaccines with adjuvants to see if they can help people develop an immune response against the virus that causes AIDS. It involves 42 participants at multiple sites in the

Waitlist Available

Alabama CRS (Site ID: 31788) (+2 Sites)

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IMARA for Sexual Activity

"This trial aims to study how different factors affect the sexual health of Black girls, including sexually transmitted infections (STIs), HIV, and sexual violence. The research will involve Black male caregivers to help protect

Waitlist Available

University of Illinois Chicago

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Behavioral Activation, Nutrition, and Activity Intervention for HIV/AIDS

"This trial will investigate if a program to help people over 50 with HIV is feasible. The program involves a coach who will motivate participants to be more active, reduce loneliness, and eat healthier."

Waitlist Available

University of Maryland, BaltimoreAnn Gruber-Baldini, PhD

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ACU-D1 for Squamous Intraepithelial Lesion

This trial is testing a drug called ACU-D1 in people who have HIV and HPV-related vulvar and perianal lesions. The main goals of the study are to determine the highest dose of

Waitlist Available

Grady Memorial HospitalLisa Flowers, MD, MPH

Have you considered Emtricitabine clinical trials? We made a collection of clinical trials featuring Emtricitabine, we think they might fit your search criteria.

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CTI-MLP assessment for HIV/AIDS

This trial seeks to understand how legal aid affects the HIV care of formerly incarcerated individuals, as well as the effectiveness of training providers in communication and medical legal partnerships.

University of Central Florida

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Dyadic Case Management for Case Management

This trial will test whether case management can help people living with HIV/on PrEP improve financial wellbeing, access food, and stay linked to care for better viral suppression.

University of ChicagoJohn Schneider, MD

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Alcohol's Impact on Men's Sexual Risk Behavior

This trial explores the link between drinking, sexual risk behavior, and sexual aggression in men. It investigates how emotions, alcohol, and stress impact men's decisions to engage in sexual risk behavior and how lab results compare to real-world behavior.

Waitlist Available

Arizona State UniversityKelly Davis, PhD

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Prebiotics for AUD and HIV/AIDS

This trial is studying the effects of alcohol use disorder and HIV on gut health, inflammation, and brain health. It will test whether a prebiotic intervention can help reduce inflammation and improve gut health in HIV+ people with/without AUD.

Ali Keshavarzian

Have you considered Emtricitabine clinical trials? We made a collection of clinical trials featuring Emtricitabine, we think they might fit your search criteria.

Explore trials for Emtricitabine

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