Diabeta

Glycemic Control, Type 2 Diabetes, Gestational Diabetes Mellitus
Treatment
3 FDA approvals
20 Active Studies for Diabeta

What is Diabeta

GlyburideThe Generic name of this drug
Treatment SummaryGlyburide is a type 2 diabetes medication prescribed to patients who cannot control their diabetes with the standard first-line treatment, metformin. It works by stimulating the release of insulin from the pancreas and increasing the levels of potassium and calcium ions inside cells. Glyburide was approved by the FDA in 1984 and an extended-release formula with metformin was approved in 2000.
Micronaseis the brand name
image of different drug pills on a surface
Diabeta Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Micronase
Glyburide
1984
341

Approved as Treatment by the FDA

Glyburide, also known as Micronase, is approved by the FDA for 3 uses which include Type 2 Diabetes Mellitus and Type 2 Diabetes .
Type 2 Diabetes Mellitus
Helps manage Type 2 Diabetes Mellitus
Type 2 Diabetes
Helps manage Type 2 Diabetes Mellitus
Glycemic Control
Used to treat Glycemic Control in combination with Metformin

Effectiveness

How Diabeta Affects PatientsGlyburide is a medication that helps the body make more insulin. It works by closing the channels in the pancreas that control the amount of potassium and calcium, which helps to increase insulin production. Patients taking glyburide should typically take a dose of 0.75mg once a day, but this dose may increase up to 10mg or more. However, there is an increased risk of cardiovascular mortality when taking glyburide, as with another drug (tolbutamide) in the same family of medications.
How Diabeta works in the bodyGlyburide is a drug that helps your body control its blood sugar levels. It belongs to a group of medicines called sulfonylureas. Glyburide works by blocking the potassium channels on your pancreas's beta cells. These potassium channels usually close when the glucose level in your body is high, causing your cells to release insulin. However, with Glyburide, the potassium channels stay closed, so your cells are forced to release more insulin. This helps keep your blood sugar levels stable.

When to interrupt dosage

The proposed measure of Diabeta is subject to the diagnosed affliction, including Glycemic Control, Type 2 Diabetes and Gestational Diabetes. The amount of dosage is contingent upon the mode of administration (e.g. Oral or Tablet) featured in the table beneath.
Condition
Dosage
Administration
Type 2 Diabetes
, 1.25 mg, 2.5 mg, 1.5 mg, 3.0 mg, 6.0 mg, 5.0 mg, 6.0 mg/mL, 0.6 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral
Gestational Diabetes Mellitus
, 1.25 mg, 2.5 mg, 1.5 mg, 3.0 mg, 6.0 mg, 5.0 mg, 6.0 mg/mL, 0.6 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral
Glycemic Control
, 1.25 mg, 2.5 mg, 1.5 mg, 3.0 mg, 6.0 mg, 5.0 mg, 6.0 mg/mL, 0.6 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral

Warnings

Diabeta has six contraindications and should not be administered together with the afflictions mentioned in the following table.Diabeta Contraindications
Condition
Risk Level
Notes
Type 1 Diabetes
Do Not Combine
Acidosis
Do Not Combine
Comatose
Do Not Combine
Diabetic Ketoacidosis
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Glyburide may interact with Pulse Frequency
There are 20 known major drug interactions with Diabeta.
Common Diabeta Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be decreased when combined with Glyburide.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be decreased when combined with Glyburide.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Glyburide.
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Glyburide.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Glyburide.
Diabeta Toxicity & Overdose RiskThe lowest toxic dose of the drug in rats has been found to be greater than 3200mg/kg, in mice greater than 1500mg/kg, in rabbits greater than 10,000mg/kg and in guinea pigs greater than 1500mg/kg. People who overdose on the drug may experience low blood sugar. Mild cases of hypoglycemia can be treated with oral glucose and changes in medication or meal schedules. Severe hypoglycemia can cause coma, seizures and neurological issues and requires immediate hospitalization with intravenous glucose and monitoring for 24-48 hours.
image of a doctor in a lab doing drug, clinical research

Diabeta Novel Uses: Which Conditions Have a Clinical Trial Featuring Diabeta?

At present, 196 active clinical trials are being conducted to evaluate the potential of Diabeta in delivering Gestational Diabetes, Glycemic Control and Type 2 Diabetes relief.
Condition
Clinical Trials
Trial Phases
Type 2 Diabetes
175 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1
Gestational Diabetes Mellitus
33 Actively Recruiting
Not Applicable, Phase 4, Phase 2, Phase 3, Early Phase 1
Glycemic Control
2 Actively Recruiting
Not Applicable

Diabeta Reviews: What are patients saying about Diabeta?

5Patient Review
3/3/2013
Diabeta for Type 2 Diabetes Mellitus
Diabeta is great, but it's expensive. I was put on Metformin by my doctor, but it doesn't control blood sugar as well and made me sick. The pharmacist says it may be the binders that hold the drug together; could this be true?
4.3Patient Review
6/15/2010
Diabeta for Type 2 Diabetes Mellitus
I found this drug to be very effective when taken in combination with Glucophage.
1.7Patient Review
9/28/2009
Diabeta for Type 2 Diabetes Mellitus

Patient Q&A Section about diabeta

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Which of the following are side effects of glyburide DiaBeta )?

"The following are all symptoms of indigestion: diarrhea, dizziness, headache, heartburn, nausea, gas, and weight gain."

Answered by AI

What is DiaBeta used for?

"DiaBeta is a drug used to help regulate blood sugar levels and treat type 2 diabetes. DiaBeta is available as a generic drug."

Answered by AI

When should you take DiaBeta?

"Swallow the capsule whole and do not crush, chew, or open it.

The doctor usually tells patients to take this medication once a day, either with breakfast or the first main meal of the day. Some patients, especially those taking higher doses, may need to take it twice a day. It's important to swallow the capsule whole and not to crush, chew, or open it."

Answered by AI

What type of drug is DiaBeta?

"Glyburide, marketed as Diabeta, is a medication used to treat type 2 diabetes. Glyburide falls under the drug class of sulfonylureas, which work by stimulating the pancreas to release insulin in order to lower blood sugar levels."

Answered by AI

Clinical Trials for Diabeta

Have you considered Diabeta clinical trials? We made a collection of clinical trials featuring Diabeta, we think they might fit your search criteria.
Have you considered Diabeta clinical trials? We made a collection of clinical trials featuring Diabeta, we think they might fit your search criteria.
Have you considered Diabeta clinical trials? We made a collection of clinical trials featuring Diabeta, we think they might fit your search criteria.
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