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What is Dextroamphetamine Sulfate
DextroamphetamineThe Generic name of this drug
Treatment SummaryDextroamphetamine is a stimulant drug used to treat attention deficit hyperactivity disorder (ADHD). It is the dextrorotary enantiomer of amphetamine and was approved by the FDA in 2001.
Dextrostatis the brand name
Dextroamphetamine Sulfate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Dextrostat
Dextroamphetamine
1975
569
Approved as Treatment by the FDA
Dextroamphetamine, also known as Dextrostat, is approved by the FDA for 2 uses such as Attention Deficit Hyperactivity Disorder and Narcolepsy .Attention Deficit Hyperactivity Disorder
Used to treat Attention Deficit Hyperactivity Disorder (ADHD) in combination with Amphetamine
Narcolepsy
Helps manage Narcolepsy
Effectiveness
How Dextroamphetamine Sulfate Affects PatientsDextroamphetamine is a drug that increases blood pressure and heart rate, improves breathing, and acts as a stimulant to the central nervous system. It is not completely understood how dextroamphetamine works in the body.
How Dextroamphetamine Sulfate works in the bodyAmphetamines work to increase the amount of dopamine in the brain by preventing its reuptake, encouraging its release and allowing it to reverse-transport. Recent findings also suggest amphetamines can affect how many dopamine transporters are in the brain.
When to interrupt dosage
The prescribed measure of Dextroamphetamine Sulfate relies upon the determined condition. The amount of dosage fluctuates as per the approach of delivery (e.g. Tablet or Oral) documented in the following table.Condition
Dosage
Administration
Attention Deficit Hyperactivity Disorder
, 5.0 mg, 10.0 mg, 15.0 mg, 5.0 mg/mL, 2.5 mg, 7.5 mg, 20.0 mg, 30.0 mg, 3.125 mg, 6.25 mg, 9.375 mg, 12.5 mg, 1.875 mg, 1.25 mg, 3.75 mg, 25.0 mg, 18.75 mg, 60.0 mg, 40.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Liquid, Liquid - Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Capsule - Oral, Capsule
Narcolepsy
, 5.0 mg, 10.0 mg, 15.0 mg, 5.0 mg/mL, 2.5 mg, 7.5 mg, 20.0 mg, 30.0 mg, 3.125 mg, 6.25 mg, 9.375 mg, 12.5 mg, 1.875 mg, 1.25 mg, 3.75 mg, 25.0 mg, 18.75 mg, 60.0 mg, 40.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Liquid, Liquid - Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Capsule - Oral, Capsule
Warnings
Dextroamphetamine Sulfate ContraindicationsCondition
Risk Level
Notes
Hypertensive disease
Do Not Combine
Drug abuse
Do Not Combine
Pulse Frequency
Do Not Combine
Open-angle glaucoma
Do Not Combine
symptomatic cardiovascular disease
Do Not Combine
advanced arteriosclerosis
Do Not Combine
Hyperthyroidism
Do Not Combine
Agitation
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Dextroamphetamine may interact with Pulse Frequency
Common Dextroamphetamine Sulfate Drug Interactions
Drug Name
Risk Level
Description
Clonidine
Major
The metabolism of Clonidine can be decreased when combined with Dextroamphetamine.
Dacomitinib
Major
The metabolism of Dacomitinib can be decreased when combined with Dextroamphetamine.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Dextroamphetamine.
Erlotinib
Major
The metabolism of Erlotinib can be decreased when combined with Dextroamphetamine.
Flecainide
Major
The metabolism of Flecainide can be decreased when combined with Dextroamphetamine.
Dextroamphetamine Sulfate Toxicity & Overdose RiskTaking dextroamphetamine has been known to cause birth defects in mice, but not rats or rabbits. It is not known how it affects human pregnancies, so it is important to weigh the risks and benefits of taking it while pregnant. Children born to mothers who take dextroamphetamine while pregnant may have deformities, faulty connections between the trachea and esophagus, anal blockage, low birthweight, or withdrawal symptoms. Mothers should not take dextroamphetamine while nursing as it can be passed to the baby through breast milk. Children under 3 years old and long-term effects in pediatric patients are unknown and should be
Dextroamphetamine Sulfate Novel Uses: Which Conditions Have a Clinical Trial Featuring Dextroamphetamine Sulfate?
Currently, 84 active trials are evaluating the capacity of Dextroamphetamine Sulfate to mitigate symptoms of Narcolepsy.Condition
Clinical Trials
Trial Phases
Narcolepsy
10 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 4, Phase 1
Attention Deficit Hyperactivity Disorder
71 Actively Recruiting
Phase 4, Not Applicable, Phase 1, Phase 2, Phase 3, Early Phase 1
Dextroamphetamine Sulfate Reviews: What are patients saying about Dextroamphetamine Sulfate?
5Patient Review
11/25/2007 I've tried other medications, and the effects of this one are by far the best. I'm alert and in control of my actions. It only takes 20 minutes to start working.
5Patient Review
2/22/2008 This medication has completely changed my life for the better. I've been taking it for 3 years now and have no intention of stopping.
5Patient Review
9/15/2008 I'm not sure if these pills are just sugar or if they actually work, but I've been feeling better since taking them.
4.3Patient Review
9/24/2007 This is, by far, the best medicine I have ever used for ADHD. In fact, I've tried them all at this point. The only issue I have with it is tolerance; however, even that hasn't stopped me from using it for nine years now.
4.3Patient Review
12/7/2007 I've been on this medication for ADD for over a decade now, and it's the only one that's ever really worked for me. My main concern is that there isn't enough information out there about potential long-term effects of the drug; unfortunately, I guess it's too late for me to do anything about that now.
4.3Patient Review
3/23/2008 I've been on this medication for a while now, but I find it hard to get clear information about it. I'm currently taking 20mg SR in the morning- should I up my dose? Additionally, how long does it stay in your system?
4Patient Review
12/3/2008 This treatment is effective if you follow your doctor's orders and get retested as needed.
2.3Patient Review
10/5/2008 I take this medication to help me stay awake during the day, but unfortunately it doesn't seem to be working very well for me. I still fall asleep without warning.
1Patient Review
9/27/2008 I did not like this treatment for my nephew. He only used it for two days, but I could tell it was having a negative effect on him. He looked like someone who was addicted to drugs or meth. He's only ten years old and has been on everything, but nothing seems to work. The doctor wrote him a prescription for Dexedrine 10mg, but I have been reading up on it and it says that for children 6-12 years old the starting dose should be 5mg, not 10mg. So please advise me on what to do next.
Patient Q&A Section about dextroamphetamine sulfate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the brand name for dextroamphetamine sulfate?
"Both dextroamphetamine and amphetamine stimulate the central nervous system. Dextroamphetamine is the active ingredient in Dexedrine, while amphetamine is the active ingredient in Adderall."
Answered by AI
Is Adderall the same as dextroamphetamine sulfate?
"Adderall has both amphetamine and dextroamphetamine while Dexedrine is just dextroamphetamine. This combination is more effective in controlling associated symptoms compared to Dexedrine."
Answered by AI
What does dextroamphetamine sulfate do?
"Dextroamphetamine is used to treat ADHD by changing the amounts of certain natural substances in the brain. Dextroamphetamine belongs to a class of drugs known as stimulants."
Answered by AI
Is dextroamphetamine as strong as Adderall?
"Adderall and Dexedrine are two of the most widely prescribed medications used to treat ADHD and contain the active ingredient amphetamine. Dexedrine contains the most potent form of amphetamine, while Adderall contains a mixture of both active forms."
Answered by AI