What is Desonate
DesonideThe Generic name of this drug
Treatment SummaryA non-fluorinated corticosteroid medication used to reduce inflammation on the skin caused by certain skin conditions.
Desonideis the brand name
Desonate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Desonide
Desonide
1984
59
Effectiveness
How Desonate Affects PatientsDesonide is a type of synthetic steroid used to treat skin inflammation and itching. This steroid is applied directly to the affected area of skin.
How Desonate works in the bodyDesonide is a topical steroid used to stop inflammation and itching. It works by binding to receptors in cells. This binding sends a signal that tells certain genes to turn on or off. It's believed that this process also stops certain chemicals that lead to inflammation from forming, like prostaglandins and leukotrienes. These chemicals are made from the release of arachidonic acid, which desonide stops by blocking the enzyme that releases it.
When to interrupt dosage
The prescribed dosage of Desonate is contingent upon the diagnosed condition, like Ocular Inflammation, Dermatosis and Dermatitis, Atopic. The amount likewise relies upon the technique of delivery (e.g. Ointment or Topical) as specified in the table below.Condition
Dosage
Administration
Ocular Inflammation
, 0.0005 mg/mg, 0.5 mg/mL, 0.05 %, 0.003 mg/mg
Ointment, Topical, Ointment - Topical, Lotion, Gel - Topical, Aerosol, foam - Topical, Lotion - Topical, , Cream - Topical, Gel, Cream, Aerosol, foam
Dermatosis
, 0.0005 mg/mg, 0.5 mg/mL, 0.05 %, 0.003 mg/mg
Ointment, Topical, Ointment - Topical, Lotion, Gel - Topical, Aerosol, foam - Topical, Lotion - Topical, , Cream - Topical, Gel, Cream, Aerosol, foam
Dermatitis, Atopic
, 0.0005 mg/mg, 0.5 mg/mL, 0.05 %, 0.003 mg/mg
Ointment, Topical, Ointment - Topical, Lotion, Gel - Topical, Aerosol, foam - Topical, Lotion - Topical, , Cream - Topical, Gel, Cream, Aerosol, foam
Dermatitis, Atopic
, 0.0005 mg/mg, 0.5 mg/mL, 0.05 %, 0.003 mg/mg
Ointment, Topical, Ointment - Topical, Lotion, Gel - Topical, Aerosol, foam - Topical, Lotion - Topical, , Cream - Topical, Gel, Cream, Aerosol, foam
Warnings
There are 20 known major drug interactions with Desonate.Common Desonate Drug Interactions
Drug Name
Risk Level
Description
Bacillus calmette-guerin substrain russian BCG-I live antigen
Major
The therapeutic efficacy of Bacillus calmette-guerin substrain russian BCG-I live antigen can be decreased when used in combination with Desonide.
Capmatinib
Major
The serum concentration of Capmatinib can be decreased when it is combined with Desonide.
Lumateperone
Major
The serum concentration of Lumateperone can be decreased when it is combined with Desonide.
Ranolazine
Major
The metabolism of Ranolazine can be increased when combined with Desonide.
Rimegepant
Major
The metabolism of Rimegepant can be increased when combined with Desonide.
Desonate Novel Uses: Which Conditions Have a Clinical Trial Featuring Desonate?
Presently, two active clinical trials are being conducted to evaluate the potential of Desonate to alleviate Atopic Dermatitis, Dermatosis and Ocular Inflammation.Condition
Clinical Trials
Trial Phases
Dermatitis, Atopic
0 Actively Recruiting
Dermatosis
0 Actively Recruiting
Ocular Inflammation
2 Actively Recruiting
Phase 2, Phase 4
Dermatitis, Atopic
0 Actively Recruiting
Desonate Reviews: What are patients saying about Desonate?
5Patient Review
11/12/2008 This medication has been a godsend for our 14 month old son who suffers from severe eczema, allergies and asthma. We have tried many other topical creams and ointments (e.g., Mymix, Protopic, Hydrocortisone creams and ointments, Aquaphor, Eucerin) to keep his eczema under control, but Desonate by far has worked the best. In order to see the best results we found that you MUST apply it consistently. As a mother, I am relieved that we finally found a medication that relieves the pain of eczema
5Patient Review
5/7/2017 Desonate is pretty pricey, but it cleared up my rash in just a couple of days. It's well worth the money, in my opinion.
5Patient Review
4/12/2013 I've been absolutely amazed by how quickly and effectively this gel has worked on my radiation rash. It's completely cleared up within minutes, which is a huge relief since it's been bothering me for weeks.
5Patient Review
12/10/2014 I was really struggling with dry, chafed skin around my chin a few years ago. I tried using Eucerin and Aquaphor, but those only provided temporary relief for a few hours. Desonate completely healed the issue within just three days. I'm really impressed and my skin is back to normal now.
4.7Patient Review
8/21/2009 I've only been using this treatment for a few weeks, but it has already made a visible difference in the condition of my skin.
4.7Patient Review
12/13/20074.3Patient Review
5/18/2009 Desonate has really helped me a lot with my eczema. It's an odorless gel which is great, and it doesn't make my skin oily or anything. I've been using it for a year on and off, and it's by far the best drug I've tried.
Patient Q&A Section about desonate
Is Desonide the same as hydrocortisone?
"Overall, desonide ointment was a more effective treatment than 1% hydrocortisone ointment, with faster improvement and similar safety." - Anonymous Online Contributor
Unverified Answer
What is Desonate used for?
"This medication is used to treat a variety of skin conditions. It reduces the swelling, itching, and redness that can occur in these types of conditions." - Anonymous Online Contributor
Unverified Answer
Is Desonate gel a steroid?
"Desonide is a medication that can come in many forms and is used to relieve inflammation and itching caused by various skin conditions, including atopic dermatitis." - Anonymous Online Contributor
Unverified Answer
Is Desonate generic?
", Cintex launched Teresina Holdings' AB-rated generic version of LEO Pharma's Desonate (desonide) topical gel. Desonate is approved for the treatment of mild to moderate atopic dermatitis in patients 3 months of age and older.Desonate is also available generically as a cream, ointment and lotion." - Anonymous Online Contributor
Unverified Answer