What is Deferiprone
DeferiproneThe Generic name of this drug
Treatment SummaryDeferiprone is a medication used to treat iron overload caused by thalassemia, a hereditary condition that affects the production of hemoglobin in the body. Deferiprone helps the body remove excess iron from the bloodstream, allowing for normal production of red blood cells. It was approved by the FDA in 2011 and is used when other treatments fail.
Ferriproxis the brand name
Deferiprone Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Ferriprox
Deferiprone
2011
10
Effectiveness
How Deferiprone works in the bodyDeferiprone is a drug that binds to iron in the body, forming a complex. This complex is then eliminated in the urine. Deferiprone is more likely to bind to iron than other metals like zinc, copper, and aluminum.
When to interrupt dosage
The measure of Deferiprone is contingent upon the diagnosed malady, including Disease, iron and Iron Deficiency Anemia. The amount likewise fluctuates as per the approach of administration (e.g. Tablet, film coated or Tablet) provided in the table underneath.Condition
Dosage
Administration
Disease
500.0 mg, , 1000.0 mg, 100.0 mg/mL
Tablet, film coated, Tablet, , Oral, Tablet, coated, Solution, Solution - Oral, Tablet - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, coated - Oral, Tablet, film coated - Oral
iron
500.0 mg, , 1000.0 mg, 100.0 mg/mL
Tablet, film coated, Tablet, , Oral, Tablet, coated, Solution, Solution - Oral, Tablet - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, coated - Oral, Tablet, film coated - Oral
Iron Deficiency Anemia
500.0 mg, , 1000.0 mg, 100.0 mg/mL
Tablet, film coated, Tablet, , Oral, Tablet, coated, Solution, Solution - Oral, Tablet - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, coated - Oral, Tablet, film coated - Oral
Warnings
Deferiprone ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Deferiprone may interact with Toxoplasma Infections
Common Deferiprone Drug Interactions
Drug Name
Risk Level
Description
Technetium Tc-99m oxidronate
Major
Deferiprone may decrease effectiveness of Technetium Tc-99m oxidronate as a diagnostic agent.
Aclidinium
Minor
Deferiprone may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Deferiprone may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Deferiprone may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Almasilate
Minor
Deferiprone may decrease the excretion rate of Almasilate which could result in a higher serum level.
Deferiprone Toxicity & Overdose RiskTaking too much of this drug can lead to a decrease in white blood cells, which can cause fatal infections. It can also damage the liver, as well as cause diarrhea, stomach ulcers, nausea, and other gastrointestinal problems. These are the most common side effects that lead to people stopping the medication.
Deferiprone Novel Uses: Which Conditions Have a Clinical Trial Featuring Deferiprone?
99 active investigations are presently examining the potential of Deferiprone to mitigate Disease, Iron Overload and Iron Deficiency Anemia.Condition
Clinical Trials
Trial Phases
Disease
0 Actively Recruiting
iron
0 Actively Recruiting
Iron Deficiency Anemia
107 Actively Recruiting
Phase 1, Not Applicable, Phase 2, Phase 3, Phase 4
Deferiprone Reviews: What are patients saying about Deferiprone?
5Patient Review
5/24/2015 I found this treatment really helpful for my gout and brain fog. The inflammation went away quickly and I had more energy and could concentrate better. My blood pressure also normalized.
Patient Q&A Section about deferiprone
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is deferiprone used for?
"This medication is used to remove excess iron from the body in adults and children 3 years of age and older who suffer from thalassemia (an inherited condition which leads to a low number of red blood cells)."
Answered by AI
How do you take FERRIPROX?
"You should take this medication three times per day. The first dose should be taken in the morning, the second at midday, and the third in the evening. If you experience nausea, it may help to take this medication with food."
Answered by AI
What does FERRIPROX do?
"Ferriprox® (deferiprone) is a prescription medicine that is used to treat iron overload that is a result of blood transfusions in people who have thalassemia syndromes, sickle cell disease, or other anemias."
Answered by AI
What is the use of deferasirox?
"Deferasirox is used to remove excess iron from the body in patients who have had too many blood transfusions and in patients with non-transfusion dependent thalassemia syndromes. It is an iron chelator (binder) that combines with iron in the blood."
Answered by AI