Decitabine

Anemia, Anemia, Refractory, Anemia + 6 more

Treatment

20 Active Studies for Decitabine

Treatment for

Anemia

What is Decitabine

DecitabineThe Generic name of this drug

Treatment SummaryGuadecitabine is a medication being studied as a treatment option for colorectal cancer that has not responded to other treatments.

Dacogenis the brand name

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Decitabine Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Dacogen

Decitabine

1996

When to interrupt dosage

The suggested measure of Decitabine is contingent upon the determined affliction. The amount of dosage may differ, in accordance with the technique of administration featured in the table beneath.

Condition

Dosage

Administration

Anemia

, 5.0 mg/mL, 50.0 mg, 35.0 mg

, Injection, powder, lyophilized, for solution, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, Injection - Intravenous, Powder - Intravenous, Powder, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral

Anemia, Refractory

, 5.0 mg/mL, 50.0 mg, 35.0 mg

Anemia

, 5.0 mg/mL, 50.0 mg, 35.0 mg

Chronic Myelomonocytic Leukemia

, 5.0 mg/mL, 50.0 mg, 35.0 mg

Myelodysplastic Syndrome

, 5.0 mg/mL, 50.0 mg, 35.0 mg

Anemia

, 5.0 mg/mL, 50.0 mg, 35.0 mg

IPSS High Risk

, 5.0 mg/mL, 50.0 mg, 35.0 mg

Myelodysplastic Syndromes

, 5.0 mg/mL, 50.0 mg, 35.0 mg

Myelodysplastic Syndromes

, 5.0 mg/mL, 50.0 mg, 35.0 mg

Warnings

There are 20 known major drug interactions with Decitabine.

Common Decitabine Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Decitabine is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Decitabine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abatacept

Major

The risk or severity of adverse effects can be increased when Decitabine is combined with Abatacept.

Abetimus

Major

The risk or severity of adverse effects can be increased when Decitabine is combined with Abetimus.

Acteoside

Major

The risk or severity of adverse effects can be increased when Decitabine is combined with Acteoside.

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Decitabine Novel Uses: Which Conditions Have a Clinical Trial Featuring Decitabine?

No active trials are currently assessing Decitabine's potential to address unspecified medical conditions.

Condition

Clinical Trials

Trial Phases

Myelodysplastic Syndrome

106 Actively Recruiting

Phase 1, Phase 2, Phase 3, Not Applicable

Chronic Myelomonocytic Leukemia

53 Actively Recruiting

Phase 1, Phase 2, Phase 3, Early Phase 1

Anemia

0 Actively Recruiting

Anemia

0 Actively Recruiting

Anemia

0 Actively Recruiting

Anemia, Refractory

0 Actively Recruiting

IPSS High Risk

0 Actively Recruiting

Myelodysplastic Syndromes

0 Actively Recruiting

Myelodysplastic Syndromes

0 Actively Recruiting

Decitabine Reviews: What are patients saying about Decitabine?

5Patient Review

1/14/2010

Decitabine for Bone Marrow Disorders Occurring Before Leukemia

This is a test review.

3.7Patient Review

10/31/2010

Decitabine for Bone Marrow Disorders Occurring Before Leukemia

The first week of treatment caused me to lose some appetite and itch my head, which then developed into a rash on my stomach. Otherwise, the treatment was okay. I have two more treatments scheduled, for a total of seven.

3.7Patient Review

11/10/2009

Decitabine for Bone Marrow Disorders Occurring Before Leukemia

After my bone marrow test revealed pre-leukemia, I had two rounds of treatment (five days in one week's time) once a month in July and August 2009 (10 IV's!). I then developed a severe infection and was hospitalized for nine days. After recovering from the infection, I received packed cells and some transfusions during this time. I am now in remission! My blood work has been checked for September/October/ and part of November 2009 and all counts are up. So far, so good!

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Patient Q&A Section about decitabine

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is decitabine a chemotherapy drug?

"DECITABINE is a chemotherapy drug that helps to reduce the growth of cancer cells. It is most often used to treat adults who have myelodysplastic syndromes."

Answered by AI

How long does it take decitabine to work?

"The median time for patients to achieve some level of remission for either CR or CRh was 2 months."

Answered by AI

What does decitabine treat?

"It works by decreasing the abnormal cells in the bone marrow. This helps the bone marrow to make healthy blood cells.

This drug is used to manage a number of conditions that impact the blood and bone marrow (myelodysplastic syndromes-MDS), in which the bone marrow does not produce a sufficient amount of healthy blood cells. People with MDS may experience issues such as infections, anemia, and easy bleeding/bruising. Decitabine is a chemotherapy drug that works by reducing the amount of abnormal cells in the bone marrow. This, in turn, helps the bone marrow to produce healthy blood cells."

Answered by AI

What class of drug is decitabine?

"Decitabine is a medication used to help the bone marrow produce normal blood cells, and to kill abnormal cells in the bone marrow."

Answered by AI

Clinical Trials for Decitabine

Have you considered Decitabine clinical trials? We made a collection of clinical trials featuring Decitabine, we think they might fit your search criteria.

Have you considered Decitabine clinical trials? We made a collection of clinical trials featuring Decitabine, we think they might fit your search criteria.