In-Home Treatment for Cancer

Overseen By Clinical Trials Referral Office

Age: 18+

Sex: Any

Trial Phase: Phase 2

Sponsor: Mayo Clinic

Must be taking: Standard cancer treatments

Must not be taking: Investigational agents

Disqualifiers: Severe disease, Continuous assistance, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Prior Safety Data This treatment has passed at least one previous human trial

Compensation: Varies

Number of Visits: Unknown

Duration: 12 weeks

27 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial examines whether receiving cancer treatment at home is more beneficial than visiting a clinic. It seeks to determine if patients feel more satisfied with their treatment when they remain at home with family and friends. The trial targets cancer patients in the Florida Panhandle and nearby areas who are managing their treatment well without major issues. Participants must have a reliable internet connection at home to maintain communication with the medical team. As a Phase 2 trial, it measures the treatment's effectiveness in an initial, smaller group of people.

Do I need to stop my current medications to join the trial?

No, you don't need to stop your current medications. The trial allows you to continue your standard cancer treatment and any other medications you are taking as part of your regular care.

What prior data suggests that this in-home cancer treatment is safe?

Research has shown that receiving cancer treatment at home is both possible and safe. Studies have found no safety concerns and report high patient satisfaction with home treatments. Early results suggest that patients receive excellent care when treated at home. No major safety issues have been reported, indicating that the treatment is well-tolerated with few side effects. This suggests that home-based cancer treatment could be a safe and comfortable option for patients. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about in-home cancer treatment because it offers a way for patients to receive standard cancer care without needing to visit a clinic. This approach can improve convenience and comfort for patients by allowing them to stay in their own homes. Additionally, it has the potential to reach people who might have difficulty traveling to medical facilities, thus increasing access to important cancer therapies. By testing this method, researchers hope to find out if receiving treatment at home can be just as effective and safe as traditional clinic-based care.

What evidence suggests that in-home cancer treatment is effective for improving treatment satisfaction?

Research has shown that receiving cancer treatment at home can significantly reduce the need to visit cancer centers, with one study reporting a 98.1% drop in visits. This trial will evaluate in-home cancer treatment through CCBW, administered according to standard clinical practice. This method is also linked to improved quality of life for patients. Early results indicate that home treatment is not only possible and safe but also well-received by patients. No major safety issues have emerged with home-based therapy. Overall, home treatment offers a satisfying alternative to traditional cancer care, especially for those in areas with limited healthcare access. ^{1 2 3 6 7}

Who Is on the Research Team?

Roxana S. Dronca, MD

Principal Investigator

Mayo Clinic

Are You a Good Fit for This Trial?

This trial is for cancer patients in the Florida Panhandle and nearby, who may benefit from receiving treatment at home instead of a clinic. It's open to those with various cancers like breast, lung, colorectal, and more. Participants should be willing to have their care managed remotely by a specialized team.

Inclusion Criteria

A social stability screener indicates patient is appropriate to participate in the CCBW program

I am 18 years old or older.

My doctor says I can perform at least limited physical activities.

Exclusion Criteria

Co-morbid systemic illnesses or other severe concurrent disease which, in the judgment of the investigator, would make the patient inappropriate for entry into this study or interfere significantly with the proper assessment of safety and toxicity of the prescribed regimens

Receiving any investigational agent which would be considered as a treatment for the primary neoplasm

Individuals who require continuous (24/7) assistance with daily living and are unable to independently manage the technology required for study participation, unless a caregiver is available and willing to provide consistent support throughout the study

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive in-home standard of care cancer treatment through CCBW for up to 12 weeks

12 weeks

In-home visits

Extension

Participants may choose to continue receiving in-home treatment for an additional 12 weeks or return to clinic setting

12 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

12 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Cancer Therapeutic Procedure

Trial Overview

The study is testing if in-home cancer treatments can increase patient satisfaction compared to traditional clinic-based care. It involves administering therapies at home with remote support from Mayo Clinic providers through the CARE Beyond Walls program.

How Is the Trial Designed?

Group I: Health services research (CCBW in-home cancer treatment) Experimental Treatment 2 Interventions

Patients receive in-home standard of care cancer-treatment through CCBW according to standard clinical practice for up to 12 weeks in the absence of disease progression or unacceptable toxicity. Following 12 weeks of in-home treatment, patients choose to return to clinic setting or continue to receive in-home treatment for an additional 12 weeks.

Who Is Running the Clinical Trial?

Mayo Clinic

Lead Sponsor

Trials

3,427

Recruited

3,221,000+

Citations

1.

pmc.ncbi.nlm.nih.gov

pmc.ncbi.nlm.nih.gov/articles/PMC3396069/

Active home-based cancer treatment - PMC - PubMed Central

This program decreased the need to access cancer facilities by 98.1%, promoted better quality of life for patients, as reflected in increased EORTC QLQ-C30 ...

2.

ascopubs.org

ascopubs.org/doi/10.1200/JCO.2025.43.17_suppl.LBA1551

Cancer Care Beyond Walls (CCBW): A randomized ...

Conclusions: Early findings support the feasibility, safety, and high patient acceptability of home-based cancer therapy. No safety concerns ...

3.

journals.sagepub.com

journals.sagepub.com/doi/10.1177/10499091251355571

Home-Based Palliative Care for Cancer Patients

Home-based palliative care is an effective approach for managing advanced-stage cancer patients, particularly in regions with limited healthcare infrastructure.

4.

clinicaltrials.gov

clinicaltrials.gov/study/NCT07285044

The Cancer Connected Access and Remote Expertise ...

This phase II trial studies whether providing cancer treatment in the home is preferred over the traditional clinic setting and if it ...

5.

pmc.ncbi.nlm.nih.gov

pmc.ncbi.nlm.nih.gov/articles/PMC11103295/

Home-based supportive care in advanced cancer: systematic ...

Home-based supportive care (HbSC) programmes for patients receiving palliative cancer care have provided more satisfactory medical practices.

6.

nhia.org

nhia.org/infusing-safety-comparing-oncology-infusion-outcomes-at-home-infusion-services-vs-hospital-based-outpatient-infusion-centers/

Infusing Safety: Comparing Oncology Infusion Outcomes at ...

This study compares safety outcomes of oncology infusions administered through home infusion (HI) to those administered in HOPDs.

7.

medscape.com

medscape.com/viewarticle/leading-centers-see-success-cancer-treatment-home-2025a1000n7o

Leading Centers See Success With Cancer Treatment at ...

Early data showed that home-based cancer therapy is feasible and safe and highly acceptable; patients reported excellent care experiences ...