Datscan
Parkinson Disease, Single-Photon Emission Computed Tomography (SPECT)
Treatment
3 FDA approvals
0 Active Studies for Datscan
Treatment for
Parkinson Disease
What is Datscan
Ioflupane I-123
The Generic name of this drug
Treatment Summary
Ioflupane (I-123) is a radioactive substance used to make images of dopamine neurons in the brain and diagnose conditions such as Parkinson's disease.
DaTscan
is the brand name
Datscan Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
DaTscan
Ioflupane I-123
2011
2
Approved as Treatment by the FDA
Ioflupane I-123, also known as DaTscan, is approved by the FDA for 3 uses such as Single-Photon Emission Computed Tomography (SPECT) and Parkinsonian Syndromes .
Single-Photon Emission Computed Tomography (SPECT)
Parkinsonian Syndromes
Parkinson Disease
Effectiveness
How Datscan Affects Patients
Iodine-123 labeled ioflupane is a drug that binds to specific neurons in the brain that contain dopamine. This binding is reversible, meaning it can easily be detached, and is used to help diagnose certain conditions.
How Datscan works in the body
Iodine-123 labeled ioflupane binds to dopamine transporters in the brain. As it decays, it releases a gamma ray which can be seen on a SPECT scan.
When to interrupt dosage
The measure of Datscan is determined by the diagnosed disorder. The amount of dosage is contingent upon the mode of delivery, as outlined in the table underneath.
Condition
Dosage
Administration
Single-Photon Emission Computed Tomography (SPECT)
, 2.0 mCi/mL, 1.998 mCi/mL
Injection, solution, Injection, solution - Intravenous, Intravenous,
Parkinson Disease
, 2.0 mCi/mL, 1.998 mCi/mL
Injection, solution, Injection, solution - Intravenous, Intravenous,
Warnings
Datscan has one contraindication, so it should not be consumed in cases of the ailments specified in the following table.
Datscan Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Datscan.
Common Datscan Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Minor
Ioflupane I-123 may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Ioflupane I-123 may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Ioflupane I-123 may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Almasilate
Minor
Ioflupane I-123 may decrease the excretion rate of Almasilate which could result in a higher serum level.
Ancestim
Minor
Ioflupane I-123 may decrease the excretion rate of Ancestim which could result in a higher serum level.
Datscan Novel Uses: Which Conditions Have a Clinical Trial Featuring Datscan?
Zero active studies are examining the potential of Datscan in providing Single-Photon Emission Computed Tomography (SPECT) diagnosis.
Condition
Clinical Trials
Trial Phases
Single-Photon Emission Computed Tomography (SPECT)
0 Actively Recruiting
Parkinson Disease
0 Actively Recruiting
Patient Q&A Section about datscan
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
What does a positive DaTscan mean?
"It is not definitive if a negative DaTscan means a person does not have PD, especially in early stages of the disease. However, a positive DaTscan can help confirm a diagnosis of PD. Additionally, a positive DaTscan can help to distinguish PD from essential tremor (ET) as there is no dopamine deficiency in ET."
Answered by AI
What is the difference between a DaTscan and an MRI?
"What is the difference between DaTscan and MRI? MRI provides detailed pictures of the brain, while DaTscan provides more detailed pictures of dopamine brain cells."
Answered by AI
How accurate is DaTscan for Parkinsons?
"In the study, DAT SPECT imaging was observed to have a high diagnostic accuracy of 98% for patients with clinically uncertain parkinsonism."
Answered by AI
What does a DaTscan diagnose?
"The DaTscan is a tool used to confirm the diagnosis of Parkinson's disease. It is a specific type of single-photon emission computed tomography (SPECT) imaging technique. This technique helps visualize dopamine transporter levels in the brain."
Answered by AI