Darifenacin

Overactive Bladder Syndrome
Treatment
20 Active Studies for Darifenacin

What is Darifenacin

DarifenacinThe Generic name of this drug
Treatment SummaryDarifenacin, sold under the brand name Enablex, is a drug prescribed for urinary incontinence. It works by blocking certain receptors in the bladder that cause muscle contractions, which reduces the urgency to urinate. It should not be used in people with urinary retention. It is unclear if being more selective in targeting the M3 receptors has any added benefit in the treatment of overactive bladder syndrome.
Enablexis the brand name
image of different drug pills on a surface
Darifenacin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Enablex
Darifenacin
2004
39

Effectiveness

How Darifenacin Affects PatientsDarifenacin is a drug that blocks the action of a specific type of receptor (muscarinic receptor) in the body. In laboratory tests, it was found to be most effective at blocking the M3 receptor. This receptor helps control things like bladder muscle contractions, saliva production, and vision. Taking this drug can cause dry mouth, constipation, and abnormal vision due to its effect on the M3 receptor.
How Darifenacin works in the bodyDarifenacin helps relax the muscles of the bladder, gastrointestinal tract, saliva glands, and eyes. It does this by blocking the activity of a specific receptor in the body, called the muscarinic M3 receptor.

When to interrupt dosage

The suggested measure of Darifenacin is based on the diagnosed condition. The quantity additionally relies upon the technique of delivery (e.g. Oral or Tablet, extended release) as mentioned in the following table.
Condition
Dosage
Administration
Overactive Bladder Syndrome
, 7.5 mg, 15.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral

Warnings

Darifenacin Contraindications
Condition
Risk Level
Notes
uncontrolled narrow-angle glaucoma
Do Not Combine
Urinary Retention
Do Not Combine
Gastric Retention
Do Not Combine
There are 20 known major drug interactions with Darifenacin.
Common Darifenacin Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Major
The risk or severity of adverse effects can be increased when Darifenacin is combined with Aclidinium.
Cimetropium
Major
The risk or severity of adverse effects can be increased when Darifenacin is combined with Cimetropium.
Eluxadoline
Major
The risk or severity of constipation can be increased when Darifenacin is combined with Eluxadoline.
Glycopyrronium
Major
The risk or severity of adverse effects can be increased when Darifenacin is combined with Glycopyrronium.
Ipratropium
Major
The risk or severity of adverse effects can be increased when Darifenacin is combined with Ipratropium.
Darifenacin Toxicity & Overdose RiskTaking too much of this drug can lead to serious nerve problems and a decrease in the effects of a neurotransmitter.
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Darifenacin Novel Uses: Which Conditions Have a Clinical Trial Featuring Darifenacin?

32 active trials are examining the potential of Darifenacin to address Overactive Bladder Syndrome.
Condition
Clinical Trials
Trial Phases
Overactive Bladder Syndrome
36 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Phase 1, Phase 2

Darifenacin Reviews: What are patients saying about Darifenacin?

4Patient Review
7/3/2016
Darifenacin for Needing to Urinate Immediately
2.3Patient Review
1/21/2020
Darifenacin for Frequent Urination
The large price increase on my Toviaz prescription led me to switch to Darifenacin. Unfortunately, this new medication was totally ineffective for me. I have to urinate at least once every 45 minutes and get up during the night 4-5 times.
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Patient Q&A Section about darifenacin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does darifenacin cause dementia?

"There was no significant difference in learning or memory between darifenacin and placebo in healthy adults, based on three studies with a total of 302 subjects."

Answered by AI

What is the best time to take darifenacin?

"You can take darifenacin before or after meals. Swallow the tablet with a drink of water. The tablet should be swallowed whole - do not chew or crush it before swallowing."

Answered by AI

What class of drug is darifenacin?

"Darifenacin is a medication that relaxes the bladder muscles to prevent urgent, frequent, or uncontrolled urination."

Answered by AI

What is the drug darifenacin used for?

"This medication is used to treat symptoms of an overactive bladder. These symptoms may include leakage of urine and a frequent need to urinate. This medicine works by relaxing the muscles of the bladder to prevent them from causing incontinence. This medicine is available only with your doctor's prescription."

Answered by AI

Clinical Trials for Darifenacin

Have you considered Darifenacin clinical trials? We made a collection of clinical trials featuring Darifenacin, we think they might fit your search criteria.
Have you considered Darifenacin clinical trials? We made a collection of clinical trials featuring Darifenacin, we think they might fit your search criteria.
Have you considered Darifenacin clinical trials? We made a collection of clinical trials featuring Darifenacin, we think they might fit your search criteria.