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What is Dalvance
DalbavancinThe Generic name of this drug
Treatment SummaryDalbavancin is an antibiotic used to treat acute bacterial skin and skin structure infections caused by certain bacteria. It works by interfering with the bacteria's cell wall, preventing them from growing and spreading. Dalbavancin is a second generation drug that is more powerful and can be taken once a week instead of multiple times a day. It is used to treat infections caused by Staphylococcus aureus, S. pyogenes, S. agalactiae, S. dysgalactiae, the S. anginosus group, and Enterococcus faecalis.
Dalvanceis the brand name
Dalvance Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Dalvance
Dalbavancin
2014
1
Effectiveness
How Dalvance Affects PatientsDalbavancin is an antibacterial drug. It is usually given in two doses, either 1000 mg followed one week later by 500 mg, or a single dose of 1500 mg. It must be given as an intravenous infusion over 30 minutes. Studies have shown that dalbavancin does not have any negative effects on heart rhythm, even at a high dose.
How Dalvance works in the bodyDalbavancin works in a similar way to vancomycin, a naturally occurring antibiotic. It kills bacteria by stopping their cells from forming cell walls. Dalbavancin forms a bond with the molecules that make up the cell wall, preventing them from being incorporated into the cell. It also alters the bacterial cell membrane and stops the bacteria from making RNA.
When to interrupt dosage
The prescribed amount of Dalvance depends on the identified condition. The dosage also fluctuates in relation to the method of delivery (e.g. Intravenous or Injection, powder, for solution) specified in the table below.Condition
Dosage
Administration
Acute Bacterial Skin and Skin Structure Infection (ABSSSI)
, 50.0 mg/mL, 500.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Powder, for solution - Intravenous, Powder, for solution
Gram Positive Bacterial Infections
, 50.0 mg/mL, 500.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Powder, for solution - Intravenous, Powder, for solution
Warnings
There are 18 known major drug interactions with Dalvance.Common Dalvance Drug Interactions
Drug Name
Risk Level
Description
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Dalbavancin.
Typhoid vaccine
Minor
The therapeutic efficacy of Typhoid vaccine can be decreased when used in combination with Dalbavancin.
(R)-warfarin
Moderate
The risk or severity of bleeding can be increased when Dalbavancin is combined with (R)-warfarin.
(S)-Warfarin
Moderate
The risk or severity of bleeding can be increased when Dalbavancin is combined with (S)-Warfarin.
4-hydroxycoumarin
Moderate
The risk or severity of bleeding can be increased when Dalbavancin is combined with 4-hydroxycoumarin.
Dalvance Toxicity & Overdose RiskTaking dalbavancin can change the bacteria in your colon and cause a condition called C. difficile-associated diarrhea. Other common side effects of taking this drug include nausea, vomiting, diarrhea, headache, rash, and itching. Very rarely, people have had blood and lymphatic system disorders, gastrointestinal disorders, liver damage, allergic reactions, low blood sugar, dizziness, difficulty breathing, hives, and changes to their blood vessels. It is not known if taking this drug is safe during pregnancy or while breastfeeding.
Dalvance Novel Uses: Which Conditions Have a Clinical Trial Featuring Dalvance?
28 active studies are examining the potential of Dalvance in ameliorating Urinary Tract Infections (UTIs).Condition
Clinical Trials
Trial Phases
Acute Bacterial Skin and Skin Structure Infection (ABSSSI)
1 Actively Recruiting
Phase 2
Gram Positive Bacterial Infections
1 Actively Recruiting
Phase 1
Dalvance Reviews: What are patients saying about Dalvance?
1Patient Review
8/8/2017 This treatment gave me a rash and hives that have lasted for 5 weeks so far.
Patient Q&A Section about dalvance
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How long does it take DALVANCE to work?
"You will need to stay still for 30 minutes while the medicine is being injected slowly through your IV tube. Even if you start to feel better after a few days, it is important to finish the full course of treatment to make sure the infection is completely cleared up."
Answered by AI
What is a DALVANCE infusion?
"Dalvance is a prescription medicine used to treat the symptoms of Acute Bacterial Skin Structure Infections. Dalvance may be used alone or with other medications. Dalvance belongs to a class of drugs called Glycopeptides."
Answered by AI
What is DALVANCE used for?
"This medication is used to treat serious bacterial infections of the skin. It works by interfering with the ability of bacteria to make proteins."
Answered by AI
What type of drug is DALVANCE?
"Dalbavancin is an antibiotic medication used to treat skin infections caused by certain types of bacteria. Dalbavancin belongs to a class of medications called lipoglycopeptide antibiotics. It works by killing bacteria. Antibiotics such as dalbavancin will not kill viruses that can cause colds, flu, or other infections."
Answered by AI