Cosopt Pf

Migraine, Open-angle glaucoma, prophylaxis of migraine headaches + 6 more
Treatment
20 Active Studies for Cosopt Pf

What is Cosopt Pf

TimololThe Generic name of this drug
Treatment SummaryDorzolamide is a type of medication used to treat high pressure in the eyes due to open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the eye that controls the balance of fluid and ions. Unlike other oral medications for glaucoma, dorzolamide has fewer side effects and does not cause acid-base or electrolyte disturbances. It was first introduced in 1995 and is available as Trusopt or Cosopt PF, which contains both dorzolamide and timolol.
Timopticis the brand name
image of different drug pills on a surface
Cosopt Pf Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Timoptic
Timolol
1978
167

Effectiveness

How Cosopt Pf Affects PatientsDorzolamide is a drug that lowers eye pressure in people with open-angle glaucoma or ocular hypertension. When taken with other medications, it can have an even stronger effect on reducing eye pressure. The peak effect of Dorzolamide usually happens around two hours after it is taken.
How Cosopt Pf works in the bodyDorzolamide is used to treat glaucoma and ocular hypertension, which are caused by an increase in pressure in the eye. This increased pressure is caused by an imbalance between the production and draining of aqueous humour, the fluid found in the eye. Dorzolamide works by inhibiting an enzyme called carbonic anhydrase II, which helps regulate the production of aqueous humour. By blocking this enzyme, Dorzolamide helps reduce aqueous humour production, thereby lowering intraocular pressure and reducing the risk of damage to the optic nerve.

When to interrupt dosage

The prescribed dose of Cosopt Pf is contingent upon the diagnosed condition, like neodynium yttrium aluminum garnet laser posterior capsulotomy, Ocular Hypertension and Increased Intra Ocular Pressure (IOP). The measure of dosage is contingent upon the method of delivery (e.g. Solution - Ophthalmic or Solution / drops) delineated in the table underneath.
Condition
Dosage
Administration
insufficient response to beta-blockers
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic
Open-angle glaucoma
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic
inadequate response to other therapeutic measures
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic
Ocular Hypertension
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic
Migraine
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic
prophylaxis of migraine headaches
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic
Open Angle Glaucoma
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic
requiring adjunctive or replacement therapy
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic
Increased Intra Ocular Pressure (IOP)
5.0 mg/mL, , 5.0 mg, 10.0 mg, 20.0 mg, 2.5 mg/mL, 6.8 mg/mL, 6.83 mg/mL, 2.56 mg/mL, 5.12 mg/mL, 0.5 %, 0.25 %, 3.4 mg/mL, 0.1 mg/mL
, Ophthalmic, Solution, Solution - Ophthalmic, Oral, Tablet, Tablet - Oral, Solution / drops, Solution / drops - Ophthalmic, Solution, gel forming, extended release, Solution, gel forming, extended release - Ophthalmic, Liquid, Liquid - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Suspension, Suspension - Ophthalmic, Solution, gel forming / drops, Solution, gel forming / drops - Ophthalmic

Warnings

Cosopt Pf has one contraindication and must not be administered when presented with any of the conditions in the table below.Cosopt Pf Contraindications
Condition
Risk Level
Notes
Lung Diseases, Obstructive
Do Not Combine
Sinus Bradycardia
Do Not Combine
Shock, Cardiogenic
Do Not Combine
second or third degree AV block
Do Not Combine
Asthma
Do Not Combine
overt cardiac failure
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Timolol may interact with Pulse Frequency
There are 20 known major drug interactions with Cosopt Pf.
Common Cosopt Pf Drug Interactions
Drug Name
Risk Level
Description
4-Bromo-2,5-dimethoxyphenethylamine
Major
The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Timolol.
4-Methoxyamphetamine
Major
The therapeutic efficacy of 4-Methoxyamphetamine can be decreased when used in combination with Timolol.
Abediterol
Major
Timolol may decrease the bronchodilatory activities of Abediterol.
Adrafinil
Major
The therapeutic efficacy of Adrafinil can be decreased when used in combination with Timolol.
Agrostis gigantea pollen
Major
The risk of a hypersensitivity reaction to Agrostis gigantea pollen is increased when it is combined with Timolol.
Cosopt Pf Toxicity & Overdose RiskThe smallest toxic dose of dorzolamide in rats is 1927mg/kg and in mice is 1320mg/kg. Symptoms of an overdose may include electrolyte imbalance, acidosis, or changes in the central nervous system. If an overdose is suspected, it is important to monitor the patient's electrolyte and pH levels and provide supportive treatment.
image of a doctor in a lab doing drug, clinical research

Cosopt Pf Novel Uses: Which Conditions Have a Clinical Trial Featuring Cosopt Pf?

34 active trials are currently being conducted to assess the potential of Cosopt PF in mitigating Ocular Hypertension, Elevated Intra Ocular Pressure (IOP) and Open Angle Glaucoma.
Condition
Clinical Trials
Trial Phases
Open-angle glaucoma
84 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2, Phase 4, Early Phase 1
Increased Intra Ocular Pressure (IOP)
0 Actively Recruiting
prophylaxis of migraine headaches
0 Actively Recruiting
requiring adjunctive or replacement therapy
0 Actively Recruiting
Migraine
52 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1
inadequate response to other therapeutic measures
0 Actively Recruiting
insufficient response to beta-blockers
0 Actively Recruiting
Ocular Hypertension
22 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4
Open Angle Glaucoma
12 Actively Recruiting
Not Applicable, Phase 3, Phase 2

Cosopt Pf Reviews: What are patients saying about Cosopt Pf?

3.3Patient Review
4/17/2014
Cosopt Pf for Wide-Angle Glaucoma
Cosopt PF has been successful in reducing my eye pressure; however, the application process is quite painful as I have dry eyes. My doctors recommended that I store it in a fridge prior to use, which does help somewhat. Additionally, taking omega-3 capsules and eyebright capsules has alleviated my dry eyes and made Cosopt PF much easier to use.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about cosopt pf

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the generic of COSOPT PF?

"A first-time generic for Cosopt® PF (dorzolamide/timolol) is now available."

Answered by AI

How much does Cosopt cost per month?

"The average cost of Cosopt PF is $49 per month. You may be able to lower your cost by using a Cosopt PF coupon from HelpRx."

Answered by AI

What is COSOPT PF for?

"This product contains two drugs used to treat high pressure inside the eye. Lowering high pressure inside the eye helps to prevent blindness. This medication works by decreasing the amount of fluid within the eye."

Answered by AI

How much does COSOPT PF cost?

"99 per vial

This medication is used to treat certain types of glaucoma and other conditions of the eye. It is also used to relieve redness of the eye and to provide lubrication for dry eyes. This medication contains a combination of two drugs: Dorzolamide and Timolol. These drugs work by decreasing the amount of fluid in the eye and by decreasing nerve impulses that can cause increased pressure in the eye.

The medication Cosopt PF is used to treat glaucoma and other conditions of the eye. It can also help relieve redness of the eye and provide lubrication for dry eyes. This medication contains a combination of two drugs: Dorzolamide and Timolol. These drugs work by decreasing the amount of fluid in the eye and by decreasing nerve impulses that can cause increased pressure in the eye."

Answered by AI

Clinical Trials for Cosopt Pf

Have you considered Cosopt Pf clinical trials? We made a collection of clinical trials featuring Cosopt Pf, we think they might fit your search criteria.
Have you considered Cosopt Pf clinical trials? We made a collection of clinical trials featuring Cosopt Pf, we think they might fit your search criteria.
Have you considered Cosopt Pf clinical trials? We made a collection of clinical trials featuring Cosopt Pf, we think they might fit your search criteria.
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