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varying protein intakes for Healthy Subjects

N/A

Recruiting

Led By Glenda Courtney-Martin, PhD

Research Sponsored by The Hospital for Sick Children

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 24 months

Awards & highlights

Study Summary

This trial will determine if increasing protein intake above the current recommended DRI produces increases in the GSH synthesis rates in erythrocytes, which protect cells from damage.

Who is the study for?

This trial is for healthy children over 22 kg, young adults aged 19-40 with a BMI under 25, and older adults aged 60-90 in good health with normal blood markers. Participants must be willing to have their diet and protein intake controlled and provide consent. Those on weight loss diets, with recent significant weight loss, chronic diseases affecting metabolism or unwilling to have blood drawn are excluded.Check my eligibility

What is being tested?

The study aims to understand how different levels of protein intake affect the production of Glutathione (GSH), an important antioxidant in our cells. Healthy participants will consume diets formulated with varying amounts of protein to see if higher intakes boost GSH synthesis rates in red blood cells across different age groups.See study design

What are the potential side effects?

Since this trial involves dietary changes rather than medication, side effects may include digestive discomfort due to new diet regimens. However, no specific side effects related to medications are expected as it's not a drug trial.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 24 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 24 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 24 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Erythrocyte GSH Fractional synthesis rates

Secondary outcome measures

Erythrocyte GSH absolute synthesis

Trial Design

1Treatment groups

Experimental Treatment

Group I: Protein intakeExperimental Treatment1 Intervention

Varying protein intakes.

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Who is running the clinical trial?

The Hospital for Sick ChildrenLead Sponsor

690 Previous Clinical Trials

6,945,423 Total Patients Enrolled

Glenda Courtney-Martin, PhDPrincipal InvestigatorAcademic &Clinical Specialist

5 Previous Clinical Trials

111 Total Patients Enrolled

Media Library

Varying protein intakes (Other) Clinical Trial Eligibility Overview. Trial Name: NCT02971046 — N/A

Healthy Subjects Research Study Groups: Protein intake

Healthy Subjects Clinical Trial 2023: Varying protein intakes Highlights & Side Effects. Trial Name: NCT02971046 — N/A

Varying protein intakes (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02971046 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this investigation exclude those aged 80 and over?

"Participants aged 6 to 90 are eligible for this trial, with 50 trials specifically designed for minors and 372 focusing on elderly individuals."

Answered by AI

How many participants has this research recruited to date?

"Correct. Clinicaltrials.gov confirms that this medical study, which was originally posted on October 1st 2020, is still actively recruiting patients. A total of 55 participants need to be accepted from a single site."

Answered by AI

Are any openings available for enrolment in this trial?

"Affirmative. The clinical trial is actively recruiting according to data available on the website clinicialtrials.gov, which was first posted in October 2020 and recently revised on January 14th 2022. 55 volunteers will be needed at a single site for this research project."

Answered by AI

What is the ideal eligibility criteria for this trial?

"This trial is looking to enrol 55 individuals - including both young children and adults. Specifically, the participants must be aged 6-90 with no history of anemia; furthermore, those within 19-40 years old should have healthily normalised blood glucose levels etcetera in accordance with their age group. Finally, each individual must present a willingness to partake in this experiment."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Glutathione (GSH) Synthesis in Healthy School-aged Children and Healthy Young and Old Adults

Glenda Courtney-Martin 2020. "Glutathione (GSH) Synthesis in Healthy School-aged Children and Healthy Young and Old Adults". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02971046.