Cleocin

Babesiosis, Mitral Valve Prolapse, Toxoplasmosis + 39 more

Treatment

18 Active Studies for Cleocin

What is Cleocin

Clindamycin

The Generic name of this drug

Treatment Summary

Clindamycin is a medication used to treat serious bacterial infections. It also has topical applications for acne. It is effective against certain bacteria, including anaerobic bacteria and gram-positive and gram-negative types. Clindamycin has also been used to treat some parasitic infections such as toxoplasmosis, malaria, and babesiosis, although it is not officially approved for this use. Clindamycin is a semi-synthetic antibiotic derived from lincomycin, which was first isolated in Lincoln, Nebraska from a soil sample.

Cleocin Hydrochloride

is the brand name

image of different drug pills on a surface

Cleocin Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Cleocin Hydrochloride

Clindamycin

1970

507

Effectiveness

How Cleocin Affects Patients

Clindamycin stops bacteria from producing proteins and is usually taken every six hours to keep a consistent amount of the antibiotic in the body. Clostridium difficile associated diarrhea (CDAD) is a possible side effect that can range from mild diarrhea to fatal colitis and may occur up to two months after stopping clindamycin. It is only used for serious infections when less toxic antibiotics cannot be used. Clindamycin works against many types of gram-positive and gram-negative bacteria, but some bacteria may be resistant to it. Depending on the area, local antibiograms can be consulted to make sure cl

How Cleocin works in the body

Clindamycin stops bacteria from making proteins. It blocks bacteria from forming ribosomes, which are responsible for creating proteins. It also stops the process of making proteins from occurring. Clindamycin is also thought to work against acne-causing bacteria, although it is not entirely understood how it does this.

When to interrupt dosage

The measure of Cleocin is contingent upon the identified disorder, including viridans group streptococci, Vaginal Infections and Surgical Intervention. The quantity of dosage is dependent upon the technique of implementation (e.g. Cream - Vaginal or Suspension - Topical) featured in the table beneath.

Condition

Dosage

Administration

Acne Vulgaris

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Surgical Intervention

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Acquired valvular dysfunction

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Respiratory Tract Infections

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Bone and Bones

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Bacteria, Anaerobic

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Endometritis caused by Anaerobic Bacterial Infection

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

viridans group streptococci

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Bone and Bones

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Bacterial Endocarditis

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

prophylaxis of Bacterial endocarditis

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Malaria

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Candidiasis, Vulvovaginal

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Pneumonia, Pneumocystis

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Bacteria, Anaerobic

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Heart Defects, Congenital

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Heart Valve Prosthesis

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Acne Vulgaris

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

penicillins

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Hypertrophic Cardiomyopathy

150.0 mg, 300.0 mg, , 0.02 mg/mg, 75.0 mg/mL, 150.0 mg/mL, 75.0 mg, 0.01 mg/mg, 10.0 mg/mL, 6.0 mg/mL, 12.0 mg/mL, 18.0 mg/mL, 100.0 mg/mL, 10.0 mg, 0.1 mg/mg, 100.0 mg, 1.0 %, 1.2 %, 30.0 mg/mL, 60.0 mg/mL, 90.0 mg/mL, 0.012 mg/mg, 11.9 mg/mL, 5.0 mg/mg, 0.007 mg/mg, 0.01 mg/mL

, Capsule - Oral, Oral, Capsule, Vaginal, Cream, Cream - Vaginal, Granule, for solution, Granule, for solution - Oral, Topical, Gel - Topical, Gel, Suspension, Suspension - Topical, Injection, solution - Intravenous, Injection, solution, Intravenous, Solution, Swab, Swab - Topical, Kit, Kit - Topical, Aerosol, foam - Topical, Aerosol, foam, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Lotion, Lotion - Topical, Suppository, Suppository - Vaginal, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Kit - Intramuscular; Intravenous, Powder, for solution - Oral, Solution - Intramuscular; Intravenous, Solution - Intravenous, Cream - Topical, Solution - Topical, Injection, Injection - Intravenous, Powder, for solution, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Oral, Liquid, Liquid - Intramuscular; Intravenous, Injection - Intramuscular; Intravenous, Injection, solution, concentrate - Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous, Gel - Vaginal

Warnings

Cleocin has four contraindications, and its use should be avoided when one is afflicted with any of the conditions stated in the table below.

Cleocin Contraindications

Condition

Risk Level

Notes

Enterocolitis, Pseudomembranous

Do Not Combine

Crohn Disease

Do Not Combine

Ulcerative Colitis

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Clindamycin may interact with Pulse Frequency

There are 20 known major drug interactions with Cleocin.

Common Cleocin Drug Interactions

Drug Name

Risk Level

Description

Astemizole

Major

The metabolism of Astemizole can be decreased when combined with Clindamycin.

Axitinib

Major

The metabolism of Axitinib can be decreased when combined with Clindamycin.

Bromocriptine

Major

The serum concentration of Bromocriptine can be increased when it is combined with Clindamycin.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Clindamycin.

Cabergoline

Major

The serum concentration of Cabergoline can be increased when it is combined with Clindamycin.

Cleocin Toxicity & Overdose Risk

The toxic dose of clindamycin in mice and rats is 2540 mg/kg and 2190 mg/kg, respectively. No cases of overdose have been reported, but potential symptoms could include abdominal pain, nausea, vomiting, and diarrhea. In one case study, a 3-year-old child was given a daily dose of 100 mg/kg for 5 days and experienced mild abdominal pain and diarrhea. Activated charcoal can be used to reduce the amount of unabsorbed drug, but hemodialysis and peritoneal dialysis are not effective. In cases of overdose, general supportive measures are recommended.

image of a doctor in a lab doing drug, clinical research

Cleocin Novel Uses: Which Conditions Have a Clinical Trial Featuring Cleocin?

Currently, 73 active studies are being conducted to assess the potential of Cleocin in managing Bacterial Endocarditis, Acne and Pneumocystis Jirovecii Pneumonia.

Condition

Clinical Trials

Trial Phases

Respiratory Tract Infections (RTI) caused by susceptible streptococci

0 Actively Recruiting

Acne Vulgaris

2 Actively Recruiting

Phase 1, Phase 2, Early Phase 1

Mitral Valve Prolapse

1 Actively Recruiting

Not Applicable

Hypertrophic Cardiomyopathy

5 Actively Recruiting

Phase 2, Phase 3, Not Applicable, Phase 1

Surgically constructed systemic-pulmonary shunt

0 Actively Recruiting

Respiratory Tract Infections

0 Actively Recruiting

Bacteria, Anaerobic

0 Actively Recruiting

Heart Defects, Congenital

0 Actively Recruiting

Communicable Diseases

0 Actively Recruiting

Bone and Bones

0 Actively Recruiting

Babesiosis

1 Actively Recruiting

Phase 2

Mixed Vaginal Infections

0 Actively Recruiting

Toxoplasmosis

1 Actively Recruiting

Phase 4

Surgical Intervention

0 Actively Recruiting

Pelvic cellulitis caused by Anaerobic Bacterial Infection

0 Actively Recruiting

Bacterial Endocarditis

0 Actively Recruiting

Malaria

0 Actively Recruiting

Acne Vulgaris

0 Actively Recruiting

Vaginal Infections

0 Actively Recruiting

Acquired Immunodeficiency Syndrome

4 Actively Recruiting

Phase 1, Phase 2, Not Applicable

Cleocin Reviews: What are patients saying about Cleocin?

5

Patient Review

11/18/2019

Cleocin for infection caused by bacteria

I found this medication to be effective, quick-acting, and helpful. I would definitely recommend it to others who are struggling with similar issues.

4.7

Patient Review

3/7/2021

Cleocin for infection caused by bacteria

Clindamycin has been really effective for me in treating tooth infections. Since I can't take other antibiotics, it's great to have an option with fewer side effects. The only downside so far is a canker sore, but that's much better than some of the alternatives.

4.3

Patient Review

2/9/2020

Cleocin for infection caused by bacteria

Please keep in mind that the people who have no problems with a medication are much less likely to look it up online and leave a comment. So, reading these comments only provides a biased survey of those who had issues while taking it.

4

Patient Review

8/3/2020

Cleocin for infection caused by bacteria

I've been prescribed Clindamycin for a bacterial skin infection. So far, I'm on day six of the twenty and have noticed an improvement. Occasionally, I get diarrhea but it's manageable with probiotics or yogurt. Additionally, I haven't experienced heartburn, nausea, or vomiting; however, there have been moments of dizziness. It took approximately four days to see a change in my rash and fourteen more days should do the trick according to my doctor.

3.3

Patient Review

12/2/2019

Cleocin for Acute Sinus Infection caused by Staphylococcus Bacteria

The medication worked to get rid of my sinus infection, but unfortunately caused a bad rash/hives. I contacted the doctor and they said it was safe to stop taking the medicine since the symptoms from the infection had gone away. They did warn me that the rash might last a few days though, as it's an allergic reaction.

3.3

Patient Review

8/9/2020

Cleocin for Skin Infection

If you have a mood disorder or anxiety disorder, I would not recommend this drug.

3.3

Patient Review

2/10/2020

Cleocin for infection caused by bacteria

It's best to take this medication with a full glass of milk, and you should stay upright for at least half an hour after swallowing the pill. If you experience heartburn, gaviscon can help. I've also found that this medication can cause drowsiness, nausea, and light diarrhea.

3

Patient Review

7/30/2019

Cleocin for infection caused by bacteria

After taking Clindamycin for two weeks to treat an infection, I started having stomach cramps and green diarrhea three days after my last dose. The pain is bad enough that I'm going to have to contact my doctor.

3

Patient Review

5/29/2021

Cleocin for Sinus Irritation and Congestion

Though this medication cleared up my sinus infection quickly, the severe diarrhea it caused a few days later was incredibly disruptive to my life. I'm now four weeks out and still struggling with these side effects; according to some people I've talked to, they could last up to six months. Use this medication at your own risk.

1

Patient Review

12/20/2020

Cleocin for infection caused by bacteria

I had an incredibly negative experience after taking clindamycin for an abscess. I developed severe heartburn, oesophagatis, rash, diarrhoea, vomiting and headache. My body has never been the same since and I would urge others to stay away from this dangerous drug.

1

Patient Review

1/5/2020

Cleocin for Sinus Irritation and Congestion

After taking just two pills of clindamycin, the nausea was so severe that I had to stop. It's been a few hours and I still can't function because I feel so sick.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about cleocin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Cleocin used to treat?

"Clindamycin is an antibiotic that is used to treat severe bacterial infections of the skin, stomach, and lungs. It can be used if you are allergic to penicillin antibiotics but has a risk of severe, life-threatening diarrhea."

Answered by AI

What infections does Cleocin treat?

"Clindamycin is an antibiotic used to treat serious infections that are caused by bacteria. It works by preventing the bacteria from making proteins."

Answered by AI

Is Cleocin a penicillin?

"Are Cleocin and Penicillin the Same Thing?

Cleocin (clindamycin hydrochloride) and penicillin are both antibiotics used to treat serious bacterial infections. However, they belong to different antibiotic drug classes - Cleocin is a lincomycin antibiotic and penicillin is a penicillin antibiotic. Therefore, they are not the same thing."

Answered by AI

Is Cleocin a strong antibiotic?

"Yes, Clindamycin is a powerful broad-based antibiotic that is prescribed by doctors to treat severe infections, including the fatal MRSA infection. It is effective against various bacterial infections, including those which can survive without air."

Answered by AI

Clinical Trials for Cleocin

Image of Los Angeles General Medical Center in Los Angeles, United States.

Decision Support Tool for HIV Treatment

18+
All Sexes
Los Angeles, CA

This study is testing software designed to help healthcare providers choose the best HIV treatment combinations for their patients. HIV medicines, known as antiretroviral therapy (ART), can be complex to manage because the right regimen depends on many factors-such as drug resistance, other health conditions, and medication schedules. Many people with HIV are cared for by general clinicians who may not have access to HIV specialists, which can make treatment decisions more challenging. In this study, healthcare providers will use patient cases to compare standard HIV treatment resources with a new clinical decision support tool that gives evidence-based ART recommendations at the point of care. The investigators hypothesize that using the tool will help providers select treatment plans that better match clinical guidelines, make decisions faster, reduce mental effort, and increase overall satisfaction with the prescribing process.

Waitlist Available
Has No Placebo

Los Angeles General Medical Center

Hayoun Lee, PhD

Image of Keck Hospital of the University of Southern California in Los Angeles, United States.

Mitral Valve Repair Procedures for Mitral Valve Prolapse

18+
All Sexes
Los Angeles, CA

The PRIMARY trial (NCT05051033), which compares mitral valve repair (MVr) to transcatheter-edge-to-edge-repair (TEER), offers a platform for conducting mechanistic studies to develop early insights into the pathophysiological processes by which mitral valve prolapse (MVP) can impact left ventricular (LV) myocardial structure and function, and, thereby, predispose to arrhythmias and sudden death. Such insights are key to identifying interventions to reduce the long-term sequelae of heart failure (HF) and arrhythmias, as well as delineate optimal therapeutic approaches for different patient sub-groups.

Recruiting
Has No Placebo

Keck Hospital of the University of Southern California (+15 Sites)

Joanna Chikwe, MD

Image of Montefiore Medical Center in Bronx, United States.

myPACE+ Algorithm for Hypertrophic Cardiomyopathy

18+
All Sexes
Bronx, NY

This will be a two-arm investigator-initiated randomized controlled study of patients with nHCM and LV ejection fraction ≥50% and NYHA II-III symptoms, normal intrinsic conduction system and pre-existing suitable dual-chamber implantable cardioverter defibrillators (ICD) systems. Patients will be randomly assigned to either personalized accelerated pacing (using the myPACE+ algorithm with mono-fractional exponent) or usual care groups. At baseline and after 3 months of pacing all patients will undergo a CPET, echocardiogram, blood work for NT-proBNP levels and complete the KCCQ-OSS and HCMSQ, questionnaires. The investigator team hypothesizes that personalized accelerated pacing will be safe and improve symptoms and heart-failure related quality of life, physical activity, pVO2, biomarkers (i.e. NT-proBNP), diastolic parameters and cardiac structure.

Recruiting
Has No Placebo

Montefiore Medical Center (+1 Sites)

Sandhya Murthy, MD

Medtronic

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We made a collection of clinical trials featuring Cleocin, we think they might fit your search criteria.
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Image of Texas Tech University Health Sciences Center in Lubbock, United States.

Amoxicillin Challenge for Penicillin Allergy

18 - 89
All Sexes
Lubbock, TX

The goal of this clinical trial is to learn about dosing when testing to see if a penicillin allergy label can be removed from adults that had been labeled as "penicillin-allergic" previously. The main question it aims to answer is: \- In penicillin-allergic patients that are at low risk of having an allergic reaction, is a one-dose oral challenge with amoxicillin (a penicillin-based antibiotic) as safe and effective as a two-dose oral challenge? Participants will, after being identified as having a low-risk penicillin allergy, be administered oral amoxicillin in a controlled setting and then monitored for an allergic reaction. Researchers will compare participants that took one dose of amoxicillin to participants that took two doses of amoxicillin (a small dose and then a larger dose) to see if either group was more likely to develop an allergic reaction.

Phase 3
Recruiting

Texas Tech University Health Sciences Center

James A Tarbox, MD

Image of Medical University of South Carolina in Charleston, United States.

Isotretinoin vs Tetracycline for Acne

Any Age
All Sexes
Charleston, SC

In the effort to find better treatments for Moderate Acne, which often relies on long-term antibiotic use, researchers are exploring alternative options. While Isotretinoin, a Vitamin A derivative, is highly effective for severe acne, its side effects limit its use for milder cases. A recent study from our institution investigated a new approach: weekly Isotretinoin dosing. The results were promising, with acne improvement and no major side effects. This suggests that weekly Isotretinoin could be a successful alternative for moderate acne in both males and females. To validate these findings, investigators propose a randomized controlled trial comparing weekly Isotretinoin to daily Doxycycline over four months. This study could confirm the safety and effectiveness of weekly Isotretinoin, as well as shed light on patient satisfaction, and long-term results compared to standard antibiotics. This research may offer a breakthrough in treating moderate acne while addressing concerns about antibiotic overuse.

Phase < 1
Recruiting

Medical University of South Carolina

Alex Richmond, MD, MSCR

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We made a collection of clinical trials featuring Cleocin, we think they might fit your search criteria.
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Image of University of California - San Francisco in San Francisco, United States.

Exercise Program for Hypertrophic Cardiomyopathy

18 - 80
All Sexes
San Francisco, CA

The EXCITE-HCM study is a randomized, controlled, blinded clinical trial designed to evaluate the effect of moderate intensity exercise training versus usual physicial activity on the improvement of HCM-related symptoms and cardiac function. About 70 participants will be recruited and randomized on a 1:1 ratio to either moderate intensity training or usual physicial activity interventions. Patients will be followed during a period of 24 weeks and assesesments as physical examination, questionnaires, 12 lead ecg's, biomarker levels, echocardiogram, Cardiac Magnetic resonance, PET and CPET will be performed to evaluate their response to the intervention.

Recruiting
Has No Placebo

University of California - San Francisco

Theodore P Abraham, M.D

Image of Rush University Medical Center in Chicago, United States.

Menstrual Cups for Vaginal Infections

15 - 35
Female
Chicago, IL

HIV remains a global pandemic with 37 million infected. In western Kenya, 16% of women in the general population and 29% of the poorest women have HIV. The HIV and sexually transmitted infection (STI) epidemics overlap with broader reproductive health concerns. Menstrual hygiene management is a big problem in low- and middle-income countries and a lack of menstrual products negatively impacts women's work-life. This comes from cultural taboos, stigma, and discrimination, promoting secrecy around menstruation, high cost of menstrual products, use of traditional materials (e.g. rags, cotton wool, etc.) causing leakage and odor, and lack of water and safe hygiene facilities. Menstrual cups designed for use during sex may help women prevent Bacterial vaginosis (BV) and STIs through hygienic period practices, and may help them avoid bad practices in an attempt to maintain vaginal dryness. The goal of this interventional trial is to test the impact of menstrual cups on vaginal microbiome, BV, and STIs of poor women at high risk for STIs and HIV. We predict to see 25% less BV, our primary outcome, over one year. This trial aims to learn more about the safety of the intervention, and understand what is needed to fully implement the program.

Phase 2
Waitlist Available

Rush University Medical Center

Image of Columbia University Irving Medical Center in New York, United States.

WiseApp for HIV

18+
All Sexes
New York, NY

This study aims to conduct a 12-month randomized controlled trial to adapt the mobile app, WiseApp, and a smart pill dispenser for Spanish-speaking people living with HIV (PLWH) in the New York City (NYC) area and La Romana, Dominican Republic (DR). The study will assess the efficacy and sustainability of WiseApp as well as identify barriers with its widespread use among Spanish speakers. With disproportionately high rates of HIV in the New York City area and the Dominican Republic, this project seeks to identify distinct contextual factors related to Spanish speaking people living with HIV and increase the likelihood of engagement with technology and improvements in clinical outcomes.

Recruiting
Has No Placebo

Columbia University Irving Medical Center

Rebecca Schnall, PhD, MPH

Image of McGill University Health Centre (Royal Victoria Hospital and Montreal General Hospital) in Montreal, Canada.

Low-Dose Trimethoprim-Sulfamethoxazole for Pneumocystis Pneumonia

18 - 100
All Sexes
Montreal, Canada

Pneumocystis jirovecii pneumonia (PJP) is an opportunistic fungal infection of immunocompromised hosts which causes in significant morbidity and mortality. The current standard of care, trimethoprim-sulfamethoxazole (TMP-SMX) at a dose of 15-20 mg/kg/day of TMP, is associated with serious adverse events, including hypersensitivity reactions, drug-induced liver injury, cytopenia, and renal failure occurring among 20-60% of patients. The frequency of adverse events increases in a dose dependent manner and commonly limits the use of TMP-SMX. Reduced treatment doses of TMP-SMX for PJP reduced ADEs without mortality differences in a recent meta-analysis of observational studies. We therefore propose a Phase III randomized, placebo-controlled trial to directly compare the efficacy and safety of low dose (10 mg/kg/day of TMP) compared to the standard-of-care (15 mg/kg/day) among patients with PJP for the primary outcome of death, new mechanical ventilation, and change of treatment.

Phase 3
Waitlist Available

McGill University Health Centre (Royal Victoria Hospital and Montreal General Hospital)

Emily G McDonald, MD MSc

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We made a collection of clinical trials featuring Cleocin, we think they might fit your search criteria.
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