Citanest Forte

Shock, Cardiogenic, Ventricular Fibrillation, Anaphylaxis + 39 more

Treatment

23 FDA approvals

20 Active Studies for Citanest Forte

Treatment for

Shock, Cardiogenic

What is Citanest Forte

Epinephrine

The Generic name of this drug

Treatment Summary

Epinephrine, also known as adrenaline, is a hormone and neurotransmitter naturally produced in the body. It has many important functions and can be used as a drug to treat hypersensitivity reactions. Since 1987, epinephrine has been available in an auto-injector form (EpiPen). It can be administered in various dosage routes, including intravenous, inhalation, nebulization, intramuscular injection, and subcutaneous injection. Common uses of parenteral epinephrine include relieving respiratory distress due to bronchospasm, treating hypersensitivity reactions, prolonging the action of infiltration

Medihaler-Epi

is the brand name

image of different drug pills on a surface

Citanest Forte Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Medihaler-Epi

Epinephrine

1956

296

Approved as Treatment by the FDA

Epinephrine, also known as Medihaler-Epi, is approved by the FDA for 23 uses including Anesthesia procedures and Bleeding .

Anesthesia procedures

Bleeding

Angioedema

Dyspnea

Urticaria

anaphylaxis

Wheezing

chest tightness

Asthma

Angioneurotic Edema

Hemostasis

severe hypersensitivity

Idiopathic Anaphylaxis

Hemostatic function

Hemorrhage

Shortness of Breath

Respiratory Sounds

Hives

Shock, Cardiogenic

Syncope

Uterine Contractions

Helps manage Uterine Contractions

Delayed Hypersensitivity

Complete Heart Block

Effectiveness

How Citanest Forte Affects Patients

Epinephrine is a drug that mimics the effect of the sympathetic nervous system, which controls how your body responds to stress. It speeds up your heart rate, strengthens your heart's contractions, and causes other bodily changes like widening of the airways and relaxing of certain muscles. It is used to treat asthma, croup, itching, hives and swelling, and other allergic reactions. It can also help with stomach and bladder issues related to anaphylaxis.

How Citanest Forte works in the body

Epinephrine helps to reduce the effects of anaphylaxis by targeting both alpha and beta-adrenergic receptors. It narrows blood vessels to limit vasodilation and reduce the risk of losing intravascular fluid volume. It also relaxes the smooth muscles of the bronchi and iris, preventing asthma-like symptoms such as wheezing and difficulty breathing. Additionally, epinephrine helps to raise blood sugar and increase the breakdown of glycogen in the liver.

When to interrupt dosage

The proposed dosage of Citanest Forte is contingent upon the indicated condition, such as Asthma, Angioneurotic Edema and Idiopathic Anaphylaxis. The portion of dosage changes, as per the administration technique featured in the following table.

Condition

Dosage

Administration

Ventricular Fibrillation

0.02 mg/mL, , 0.0091 mg/mL, 0.005 mg/mL, 0.01 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.22 mg, 0.3 mg, 0.018 mg/mL, 3.0 mg/mL, 1.5 mg/mL, 0.005 mg, 0.01 mg, 0.02 mg, 0.0091 mg, 0.15 mg, 0.5 %, 1.0 mg, 3.5 %, 0.0001 mg/mg, 0.001 mg/mL, 0.009 mg/mL, 10.0 mg/mL, 0.182 mg, 0.00016 mg, 1.91 mg, 0.1 %, 1.0 mL, 120.0 mg/mL, 0.125 mg, 0.7 mg, 0.0125 mg/mL, 0.001 mg/mg, 0.036 mg/mL, 0.0204 mg/mL, 0.0407 mg/mL, 1.0 mL/mL, 5.0 mg/mL, 0.0182 mg/mL

Subcutaneous, , Injection, solution - Subcutaneous, Injection, solution, Dental; Infiltration, Injection, solution - Dental; Infiltration, Endotracheal; Intracardiac; Intravenous, Injection, solution - Endotracheal; Intracardiac; Intravenous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intracardiac; Intramuscular; Intravenous; Subcutaneous, Injection, Parenteral, Injection - Parenteral, Respiratory (inhalation), Kit, Capsule, Injection - Subcutaneous, Injection, solution - Intravenous, Injection, solution - Infiltration; Perineural, Infiltration; Perineural, Epidural; Infiltration; Intracaudal; Perineural, Injection, solution - Epidural; Infiltration; Intracaudal; Perineural, Infiltration, Injection, solution - Infiltration, Intramuscular, Injection - Intramuscular, Intracardiac; Intravenous, Injection, solution - Intracardiac; Intravenous, Injection, solution - Epidural; Retrobulbar, Epidural; Retrobulbar, Injection, solution - Epidural; Intracaudal; Perineural, Epidural; Intracaudal; Perineural, Perineural, Injection, solution - Perineural, Dental, Injection, solution - Dental, Solution - Epidural; Infiltration, Solution - Infiltration, Solution, Epidural; Infiltration, Liquid - Infiltration, Liquid, Liquid - Epidural, Epidural, Intracardiac; Intramuscular; Intravenous; Subcutaneous, Capsule - Respiratory (inhalation), Intravenous, Solution - Nasal, Nasal, Dental; Subcutaneous, Aerosol, metered - Respiratory (inhalation), Liquid - Epidural; Infiltration, Solution / drops, Oral; Parenteral, Liquid; Tablet, Liquid; Tablet - Oral; Parenteral, Ophthalmic, Intramuscular; Oral; Subcutaneous, Liquid; Tablet - Intramuscular; Oral; Subcutaneous, Gel, Topical, Gel - Topical, Solution - Topical, Spray - Respiratory (inhalation), Packing, Packing - Dental, Intramuscular; Subcutaneous, Injection, solution - Intramuscular; Subcutaneous, Injection - Intramuscular; Subcutaneous, Injection - Submucosal, Submucosal, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Intramuscular; Intraocular; Subcutaneous, Injection - Intramuscular; Intraocular; Subcutaneous, Spray, Spray - Topical, Kit - Intramuscular; Intraocular; Subcutaneous, Injection, solution - Epidural, Injection - Intracardiac; Intravenous, Injection, solution - Epidural; Infiltration; Intracaudal, Epidural; Infiltration; Intracaudal, Endotracheal; Intracardiac; Intramuscular; Intravenous; Subcutaneous, Injection, solution - Submucosal, Solution - Intramuscular, Injection, solution - Intramuscular, Solution - Ophthalmic, Solution - Epidural, Injection, solution - Parenteral, Liquid - Subcutaneous, Solution - Intracardiac; Intravenous, Solution - Intramuscular; Intravenous; Subcutaneous, Liquid - Dental; Subcutaneous, Aerosol, metered, Solution / drops - Ophthalmic, Liquid - Intramuscular, Liquid - Intracardiac; Intravenous, Solution - Intramuscular; Subcutaneous, Intramuscular; Subcutaneous; Topical, Kit - Intramuscular; Subcutaneous; Topical, Injection, solution - Endotracheal; Intracardiac; Intramuscular; Intravenous; Subcutaneous, Solution - Endotracheal; Intracardiac; Intramuscular; Intravenous; Subcutaneous, Injection - Infiltration, Epidural; Parenteral; Retrobulbar, Injection - Epidural; Parenteral; Retrobulbar, Epidural; Parenteral, Injection - Epidural; Parenteral, Injection - Dental, Aerosol, Aerosol - Respiratory (inhalation), Injection - Intracardiac; Intramuscular; Intraspinal; Intravenous; Subcutaneous, Intracardiac; Intramuscular; Intraspinal; Intravenous; Subcutaneous, Patch - Iontophoresis, Iontophoresis, Inhalant, Inhalant - Oral, Oral, Infiltration; Intramuscular; Intravenous, Kit - Infiltration; Intramuscular; Intravenous, Infiltration; Topical, Parenteral; Topical, Kit - Infiltration; Topical, Liquid - Parenteral; Topical, Dental; Oral; Periodontal, Solution - Dental; Oral; Periodontal, Patch, Kit - Intramuscular; Subcutaneous, Injection - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Epidural; Infiltration, Endotracheal; Intramuscular; Intravenous; Subcutaneous, Solution - Endotracheal; Intramuscular; Intravenous; Subcutaneous, Infiltration; Submucosal, Injection, solution - Infiltration; Submucosal, Injection - Infiltration; Submucosal, Injection - Epidural; Infiltration; Intracaudal; Perineural, Solution - Intravenous, Injection; Kit; Swab, Injection; Kit; Swab - Intramuscular; Subcutaneous; Topical

Respiratory Distress

Shock, Cardiogenic

Bronchial Spasm

Asthma

Respiratory Sounds

Shortness of Breath

Bradycardia

Low Blood Pressure

Hemorrhage

Hemostasis

Asthma

Anesthesia, Conduction

Angioedema

Complete Heart Block

Nasal Congestion

Anesthesia procedures

Asthma

Hypersensitivity

Uterine Contractions

Warnings

Citanest Forte Contraindications

Condition

Risk Level

Notes

conditions contraindicating pressor use

Do Not Combine

Coronary Artery Disease

Do Not Combine

Shock

Do Not Combine

Pulse Frequency

Do Not Combine

Glaucoma, Angle-Closure

Do Not Combine

Disease

Do Not Combine

Anaesthesia

Do Not Combine

Neurocognitive Disorders

Do Not Combine

There are 20 known major drug interactions with Citanest Forte.

Common Citanest Forte Drug Interactions

Drug Name

Risk Level

Description

2,5-Dimethoxy-4-ethylamphetamine

Major

The therapeutic efficacy of 2,5-Dimethoxy-4-ethylamphetamine can be increased when used in combination with Epinephrine.

2,5-Dimethoxy-4-ethylthioamphetamine

Major

The therapeutic efficacy of 2,5-Dimethoxy-4-ethylthioamphetamine can be increased when used in combination with Epinephrine.

4-Bromo-2,5-dimethoxyamphetamine

Major

The therapeutic efficacy of 4-Bromo-2,5-dimethoxyamphetamine can be increased when used in combination with Epinephrine.

Abemaciclib

Major

The metabolism of Abemaciclib can be decreased when combined with Epinephrine.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be decreased when combined with Epinephrine.

Citanest Forte Toxicity & Overdose Risk

Epinephrine can be dangerous when taken in large doses. Pregnant women should only take this drug if absolutely necessary in an emergency. It may delay the second stage of labor or cause the baby’s heart rate to speed up. Common side effects include anxiety, headache, fear, palpitations, and injection site necrosis. Serious side effects can include high blood pressure, heart arrhythmias, stroke, kidney damage, pulmonary edema, and loss of blood flow to the hands and feet.

image of a doctor in a lab doing drug, clinical research

Citanest Forte Novel Uses: Which Conditions Have a Clinical Trial Featuring Citanest Forte?

282 active clinical trials are currently underway to investigate the utility of Citanest Forte in providing relief from Asthma, Allergy and Laryngotracheobronchitis.

Condition

Clinical Trials

Trial Phases

Asthma

92 Actively Recruiting

Phase 1, Phase 4, Early Phase 1, Phase 2, Not Applicable, Phase 3

Anaphylaxis

3 Actively Recruiting

Phase 1, Phase 2

Low Blood Pressure

5 Actively Recruiting

Not Applicable, Phase 4, Phase 2

Hypersensitivity

1 Actively Recruiting

Phase 4

Hemostasis

1 Actively Recruiting

Not Applicable

Hemorrhage

0 Actively Recruiting

Hives

0 Actively Recruiting

Idiopathic Anaphylaxis

0 Actively Recruiting

Shortness of Breath

10 Actively Recruiting

Phase 2, Not Applicable

Hemostatic function

0 Actively Recruiting

Local Anaesthesia therapy

0 Actively Recruiting

Anesthesia, Conduction

0 Actively Recruiting

Syncope

6 Actively Recruiting

Not Applicable, Phase 2

Septic Shock

0 Actively Recruiting

Respiratory Distress

0 Actively Recruiting

Asthma

0 Actively Recruiting

Uterine Contractions

1 Actively Recruiting

Not Applicable

Open Angle Glaucoma

10 Actively Recruiting

Phase 3, Not Applicable, Phase 4

induction of Local Anaesthesia

0 Actively Recruiting

Pupil

0 Actively Recruiting

Patient Q&A Section about citanest forte

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is another name for Citanest?

"It is also often combined with lidocaine as EMLA cream, which is used as an anesthetic for cream for superficial dermatological procedures.

Prilocaine is an anesthetic of the amino amide type that is typically used in dentistry. It is also often combined with lidocaine as EMLA cream, which is used as an anesthetic for superficial dermatological procedures."

Answered by AI

Do dentists use prilocaine?

"Prilocaine should be injected by a dentist in order to numb the mouth before a dental procedure."

Answered by AI

How long does Citanest last?

"Citanest Plain Dental Injection provides approximately 10 minutes of pulpal anesthesia based on electrical stimulation studies. In clinical studies, this has been found to provide complete anesthesia for procedures lasting an average of 20 minutes."

Answered by AI

Does Citanest contain epinephrine?

"Citanest Forte DENTAL with Epinephrine 1:200,000 is a sterile, non-pyrogenic, isotonic solution that contains a local anesthetic agent with epinephrine and is administered parenterally by injection. It is indicated for specific uses."

Answered by AI