All > Covid 19 > Anosmia

Smell training for Coronavirus

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Coronavirus+17 MoreSmell training - Other
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will help assess if olfactory training can help improve olfactory function in patients with post-COVID olfactory dysfunction.

Eligible Conditions
  • Coronavirus
  • Loss of Smell
  • Olfactory Dysfunction COVID-19
  • Reduced Sense of Smell
  • COVID-19
  • Parosmia

Treatment Effectiveness

Effectiveness Progress

1 of 3

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1
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1
IMM-BCP-01
1
DVX201

Study Objectives

5 Primary · 1 Secondary · Reporting Duration: Measurement will be taken at time zero (pre-intervention) and 12 weeks (post-intervention)

Measurement will be taken at time zero (pre-intervention)
Nasal Obstruction Symptom Evaluation (NOSE)
Week 12
Changes from baseline in olfactory score on the Sniffin's Sticks test
Changes from baseline in olfactory score on the University of Pennsylvania Identification Test (UPSIT) [ Time Frame: Measurement will be taken at time zero (pre-intervention) and 12 weeks (post-intervention)
Parosmia and phantosmia assessment test
The abridged version of the Questionnaire of Olfactory Disorders - Negative Statements (sQOD-NS)
n-house test for chemosensory dysfunction (TMSC)

Trial Safety

Safety Progress

1 of 3

Similar Trials

1
Ad5-triCoV/Mac
1
IMM-BCP-01
1
DVX201

Trial Design

3 Treatment Groups

Chemosensory training group 1
1 of 3
Chemosensory training group 2
1 of 3
Chemosensory training group 3
1 of 3

Experimental Treatment

Non-Treatment Group

105 Total Participants · 3 Treatment Groups

Primary Treatment: Smell training · Has Placebo Group · N/A

Chemosensory training group 1
Other
Experimental Group · 1 Intervention: Smell training · Intervention Types: Other
Chemosensory training group 2
Other
Experimental Group · 1 Intervention: Smell training · Intervention Types: Other
Chemosensory training group 3
Other
PlaceboComparator Group · 1 Intervention: Smell training · Intervention Types: Other

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: measurement will be taken at time zero (pre-intervention) and 12 weeks (post-intervention)

Who is running the clinical trial?

Université du Québec à Trois-RivièresLead Sponsor
36 Previous Clinical Trials
3,869 Total Patients Enrolled
Johannes A Frasnelli, PhDPrincipal InvestigatorUniversité du Québec à Trois-Rivières

Eligibility Criteria

Age 18+ · All Participants · 4 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have a positive diagnosis of COVID-19 with persistent olfactory dysfunction.

Who else is applying?

What state do they live in?
New Mexico33.3%
South Carolina33.3%
Texas33.3%
How old are they?
18 - 6575.0%
65+25.0%
What site did they apply to?
Université du Québec à Trois-Rivières100.0%
What portion of applicants met pre-screening criteria?
Met criteria25.0%
Did not meet criteria75.0%
Why did patients apply to this trial?
  • "J'ai perdu mon odorat quand j'ai eu COVID en mai. Je suis une coeliac et j'avais l'odorat formidable avant Covid. Les steroides l'ont ameliore, mais apres l'anosmie est revenue. Quelque fois je sens un peu, autres, rien. L'acupuncture m'aidait mais c'est cher d'y aller beaucoup. Je veux le retour de mon odorat."
What questions have other patients asked about this trial?
  • "Pourrais-je participer si j'habite aux Etats-Unis?"
How many prior treatments have patients received?
1100.0%
References

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