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Smell training for Coronavirus (OTTODC19 Trial)
N/A
Waitlist Available
Led By Johannes A Frasnelli, PhD
Research Sponsored by Université du Québec à Trois-Rivières
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up measurement will be taken at time zero (pre-intervention) and 12 weeks (post-intervention)
Summary
This trial will help assess if olfactory training can help improve olfactory function in patients with post-COVID olfactory dysfunction.
Eligible Conditions
- Coronavirus
- Parosmia
- Loss of Smell
- COVID-19
- Reduced Sense of Smell
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ measurement will be taken at time zero (pre-intervention) and 12 weeks (post-intervention)
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~measurement will be taken at time zero (pre-intervention) and 12 weeks (post-intervention)
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Changes from baseline in olfactory score on the Sniffin's Sticks test
Changes from baseline in olfactory score on the University of Pennsylvania Identification Test (UPSIT) [ Time Frame: Measurement will be taken at time zero (pre-intervention) and 12 weeks (post-intervention)
Parosmia and phantosmia assessment test
+2 moreSecondary study objectives
Nasal Obstruction Symptom Evaluation (NOSE)
Trial Design
3Treatment groups
Experimental Treatment
Placebo Group
Group I: Chemosensory training group 2Experimental Treatment1 Intervention
For 12 weeks, morning and evening, smell four odors namely coffee aroma, cheese aroma, strawberries, and limon, for a total of five minutes per session.
Group II: Chemosensory training group 1Experimental Treatment1 Intervention
For 12 weeks, morning and evening, smell four odors namely eucalyptol, phenyl ethanol, Orange, and eugenol, for a total of five minutes per session.
Group III: Chemosensory training group 3Placebo Group1 Intervention
For 12 weeks, morning and evening, smell four same odorless substance.
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Who is running the clinical trial?
Université du Québec à Trois-RivièresLead Sponsor
47 Previous Clinical Trials
4,414 Total Patients Enrolled
Johannes A Frasnelli, PhDPrincipal InvestigatorUniversité du Québec à Trois-Rivières
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